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Current Research News

18 November 2009

1. A Maternal But Not Paternal Association Of Ambulatory Blood Pressure With Albumin Excretion In Young Offspring With Type 1 Diabetes.
2. Inflammation markers and metabolic characteristics of subjects with one-hour plasma glucose levels.
3. Insulin Resistance in Adolescents with Type 1 Diabetes and Its Relationship to Cardiovascular Function.
4. Changes in Cerebral Blood Flow Detected by SPECT in Type 1 and Type 2 Diabetic Patients.
5. The assessment of pulmonary diffusing capacity in diabetes mellitus with regard to microalbuminuria.
6. Low levels of vitamin D in North Indian children with newly diagnosed type 1 diabetes.
7. Epidemiological perspectives on type 1 diabetes in childhood and adolescence in Germany: 20 years of the DIARY registry.
8. Early Infant Diet in Children at High Risk for Type 1 Diabetes.
9. Childhood growth and age at diagnosis with Type 1 diabetes in Colorado young people.
10. Increasing incidence of childhood type 1 diabetes in Montenegro from 1997 to 2006.
11. Testing for monogenic diabetes among children and adolescents with antibody-negative clinically defined Type 1 diabetes.

    11 November 2009

12. Epidemiological perspectives on type 1 diabetes in childhood and adolescence in Germany: 20 years of the DIARY registry.
13. Microvascular reactivity in type 1 diabetics.
14. Regulation of oxidative stress by glycaemic control: evidence for an independent inhibitory effect of insulin therapy.

    4 November 2009

15. Autologous umbilical cord blood transfusion in very young children with type 1 diabetes.
16. Maternal age at birth and childhood type 1 diabetes: a pooled analysis of 30 observational studies.
17. The Effect of Direct Renin Inhibition on Renal Hemodynamic Function, Arterial Stiffness and Endothelial Function in Humans with Uncomplicated Type 1 Diabetes Mellitus: A Pilot Study.
18. A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both HbA1c and glucose.
19. The influence of physical activity on ghrelin and IGF-1/IGFBP-3 levels in children and adolescents with type 1 diabetes mellitus.

    28 October 2009

20. Preventing hypoglycemia using predictive alarm algorithms and insulin pump suspension.
21. Closed-Loop Insulin Delivery Using a Subcutaneous Glucose Sensor and Intra-Peritoneal Insulin Delivery: A Feasibility Study Testing a New Model for the Artificial Pancreas.
22. Aortic Intima Media Thickness is an Early Marker of Atherosclerosis in Children with Type 1 Diabetes Mellitus.
23. Nephropathy in Type 1 diabetes is associated with increased circulating activated platelets and platelet hyperreactivity.
24. Daily vegetable intake during pregnancy negatively associated to islet autoimmunity in the offspring–The ABIS study.
25. Associations of Serum Concentrations of 25-Hydroxyvitamin D and Parathyroid Hormone with Surrogate Markers of Insulin Resistance among U.S. Adults without Physician-Diagnosed Diabetes: National Health and Nutrition Examination Survey, 2003-2006.

21 October 2009

26. Hippocampal Volumes in Youth with Type 1 Diabetes.
27. Subclinical vascular alterations in young adults with type 1 diabetes detected by arterial tonometry.
28. Age at Onset Of Type 1 Diabetes in Parents and Recurrence Risk in Offspring.
29. Factors for thyroid autoimmunity in children and adolescents with type 1 diabetes mellitus.
30. Latent Autoimmune Diabetes in Adults.
31. Pancreatic islet transplantation. Free full text available in HTML and PDF formats.
32. Stem cell therapy for type 1 diabetes mellitus: a review of recent clinical trials. Free full text available in PDF format.
33. Absence of diabetic retinopathy in a patient who has had diabetes mellitus for 69 years, and inadequate glycemic control: case report. Free full text available in HTML and PDF formats.

14 October 2009

34. The incidence of type 1 diabetes is increasing in both children and young adults in Northern Italy: 1984-2004 temporal trends.
35. Angiotensin-converting enzyme and angiotensin II receptor subtype 2 genotypes in type 1 diabetes and severe hypoglycaemia requiring emergency treatment: a case cohort study.
36. Early Progression of the Autonomic Dysfunction Observed in Pediatric Type 1 Diabetes Mellitus.
37. Lipid abnormalities predict progression of renal disease in patients with type 1 diabetes.
38. Prevalence of diabetic retinopathy and cataract in adult patients with type 1 and type 2 diabetes in Russia.
39. Type 1 Diabetes Development Requires Both CD4+ and CD8+ T cells and Can Be Reversed by Non-Depleting Antibodies Targeting Both T Cell Populations.

    7 October 2009

40. Incidence of Childhood Type 1 Diabetes: A Worrying Trend.
41. Ingestion of Diet Soda before a Glucose Load Augments GLP-1 Secretion.
42. Effects of Exenatide Alone and in Combination with Daclizumab on Beta Cell Function in Long-Standing Type 1 Diabetes Mellitus.
43. Efficacy and safety of AIR inhaled insulin compared to insulin lispro in patients with type 1 diabetes mellitus in a 6-month, randomized, noninferiority trial.
44. Two-year efficacy and safety of AIR inhaled insulin in patients with type 1 diabetes: An open-label randomized controlled trial.
45. Telomere length predicts all-cause mortality in patients with type 1 diabetes.
46. A Randomised Placebo Controlled Double Blind Clinical Trial of Cannabis Based Medicinal Product (Sativex) in Painful Diabetic Neuropathy: Depression is a Major Confounding Factor.
47. Regression of diabetic complications by islet transplantation in the rat.
48. The International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes--chapter 3: Pig islet product manufacturing and release testing.
49. Infection With Viruses From Several Families Triggers Autoimmune Diabetes In LEW.1WR1 Rats: Prevention of Diabetes by Maternal Immunization.

    30 September 2009

50. The July/August 2009 issue of Xenotransplantation focused on porcine islet transplantation as a cure for type 1 diabetes.
51. A rare haplotype of the vitamin D receptor gene is protective against diabetic nephropathy.
52. Increased circulating IL-8 is associated with reduced IGF-1 and related to poor metabolic control in adolescents with type 1 diabetes mellitus.
53. Improving islet transplantation: a road map for a widespread application for the cure of persons with type I diabetes.
54. Prevention of beta cell dysfunction and apoptosis by adenoviral gene transfer of rat insulin-like growth factor 1. Free full text available in HTML and PDF formats.

    23 September 2009

55. Use of a cocktail regimen consisting of soluble galectin-1, rapamycin and histone deacetylase inhibitor may effectively prevent type 1 diabetes.
56. The Diabetes Control and Complications Trial: the gift that keeps giving.
57. Progression Factors of Carotid Intima-Media Thickness and Plaque in Patients with Long-Term, Early-Onset Type 1 Diabetes Mellitus in Japan: Simultaneous Comparison with Diabetic Retinopathy. Free full text available in PDF format.
58. Anti-infectious antibodies and autoimmune-associated autoantibodies in patients with type I diabetes mellitus and their close family members.
59. Factors in serum from type 2 diabetes patients can cause cellular insulin resistance.

    16 September 2009

60. Closed-Loop Artificial Pancreas Using Subcutaneous Glucose Sensing and Insulin Delivery and a Model Predictive Control Algorithm: Preliminary Studies in Padova and Montpellier. (PDF)
61. Overnight Closed-Loop Insulin Delivery with Model Predictive Control: Assessment of Hypoglycemia and Hyperglycemia Risk Using Simulation Studies. (PDF)
62. A Closed-Loop Artificial Pancreas Using Model Predictive Control and a Sliding Meal Size Estimator. (PDF)
63. Probabilistic Evolving Meal Detection and Estimation of Meal Total Glucose Appearance. (PDF)
64. Analysis, Modeling, and Simulation of the Accuracy of Continuous Glucose Sensors.
65. From Genetic Risk Awareness to Overt Type 1 Diabetes: Parental Stress in a Placebo-Controlled Prevention Trial.
66. Predictive Characteristics of Diabetes-Associated Autoantibodies Among Children With HLA-Conferred Disease Susceptibility in the General Population.
67. Pancreatic Islet Autoantibodies as Predictors of Type 1 Diabetes in the Diabetes Prevention Trial-Type 1 (DPT-1).
68. Revisiting infant growth prior to childhood onset type 1 diabetes.
69. Genetic polymorphisms in genes encoding antioxidant enzymes are associated with diabetic retinopathy in type 1 diabetes.
70. Blindness in a 25-Year Follow-up of a Population-Based Cohort of Danish Type 1 Diabetic Patients.

    9 September 2009

71. Increasing incidence of pediatric type 1 diabetes mellitus in Southeastern Wisconsin: relationship with body weight at diagnosis. Free full text available in HTML and PDF formats.
72. Vitamin D receptor gene polymorphisms and susceptibility to type 1 diabetes in Crete, Greece.
73. Pancreas transplantation alone in children: a case report.
74. Lipid disorders in type 1 diabetes.
75. Elevated Proportions of Recent Thymic Emigrants in Children and Adolescents with Type 1 Diabetes.

    2 September 2009

76. Generation of pluripotent stem cells from patients with type 1 diabetes. Free full text available in PDF format. See also Researchers Make Insulin-Producing Cells From Adult Skin Cells.
77. Multinational study in children and adolescents with newly diagnosed type 1 diabetes: association of age, ketoacidosis, HLA status, and autoantibodies on residual beta-cell function and glycemic control 12 months after diagnosis.
78. Folic acid supplementation normalizes the endothelial progenitor cell transcriptome of patients with type 1 diabetes: a case-control pilot study.
79. Reduced endogenous secretory receptor for advanced glycation end products (esRAGE) in young people with Type 1 diabetes developing microalbuminuria.
80. Early predictors of myocardial disease in children and adolescents with type 1 diabetes mellitus.
81. Cognitive performance, symptoms and counter-regulation during hypoglycaemia in patients with type 1 diabetes and high or low renin-angiotensin system activity.
82. One hundred one simultaneous pancreas-kidney transplantations: long-term outcomes at a single center.
83. Use of small donors (<28 kg) for pancreas transplantation.
84. The Hygiene Hypothesis: Do We Still Believe in It?
85. Melatonin prolongs islet graft survival in diabetic NOD mice.

    26 August 2009

86. Epigenetics: deciphering how environmental factors may modify autoimmune type 1 diabetes.
87. Alleviation of exogenous insulin requirement in type 1 diabetes mellitus after immunoablation and transplantation of autologous hematopoietic stem cells.
88. Noninvasive radial artery tonometry augmentation index and urinary albumin/creatinine levels in early adolescents with type 1 diabetes mellitus.
89. Genetic-induced Variations in the GAD65 T-cell Repertoire Governs Efficacy of Anti-CD3/GAD65 Combination Therapy in New-onset Type 1 Diabetes.
90. No Effect of the Altered-Peptide Ligand NBI-6024 on Beta Cell Residual Function and Insulin Needs in New-Onset Type 1 Diabetes.
91. TroponinT and proBNP in fetuses of Type 1 diabetic mothers.
92. Placental structure in type 1 diabetes: relation to fetal insulin, leptin and IGF-I.
93. Caffeine consumption attenuates neurochemical modifications in the hippocampus of streptozotocin-induced diabetic rats.
94. The Ectopic Expression of Pax4 in the Mouse Pancreas Converts Progenitor Cells into alpha and Subsequently beta Cells. See also Scientists Find That a Single Gene Can Convert Pancreatic Alpha Cells Into Betas in Lab Mice.

    19 August 2009

95. Vitamin D Levels in Subjects With and Without Type 1 Diabetes Residing in a Solar Rich Environment.
96. Association of type 1 diabetes with month of birth among US youth: The SEARCH for Diabetes in Youth Study.
97. Retinal arterioles have impaired reactivity to hyperoxia in type 1 diabetes.
98. Thymus-specific deletion of insulin induces autoimmune diabetes.

    12 August 2009

99. Altered prefrontal glutamate-glutamine-gamma-aminobutyric acid levels and relation to low cognitive performance and depressive symptoms in type 1 diabetes mellitus.
100. Carotid intima-media thickness and cerebrovascular reactivity in long-term type 1 diabetes mellitus.
101. C-peptide is internalised in human endothelial and vascular smooth muscle cells via early endosomes.

     5 August 2009

102. Insulin treatment in IA-2A-positive relatives of type 1 diabetic patients.
103. Role of insulin autoantibody affinity as a predictive marker for type 1 diabetes in young children with HLA-conferred disease susceptibility.
104. Is islet autoimmunity related to insulin sensitivity or body weight in children of parents with type 1 diabetes?
105. Abnormal retinal autoregulation is detected by provoked stimulation with flicker light in well-controlled patients with type 1 diabetes without retinopathy.
106. Anti-Mullerian hormone and inhibin B levels as markers of premature ovarian aging and transition to menopause in type 1 diabetes mellitus.
107. Two studies, Vitamin D Status and Cardiometabolic Risk Factors in the United States Adolescent Population, Prevalence and Associations of 25-Hydroxyvitamin D Deficiency in US Children: NHANES 2001–2004, offer advice on supplementing vitamin D.

     29 July 2009

108. Long-term metabolic control of autoimmune diabetes in spontaneously diabetic nonobese diabetic mice by nonvascularized microencapsulated adult porcine islets.
109. HbA1c and serum levels of advanced glycation and oxidation protein products in poorly and well controlled children and adolescents with type 1 diabetes mellitus.
110. Incidence of insulin-requiring diabetes in the US military.
111. Temporal Trends In Incidence Of Type 1 Diabetes Between 1986 And 2006 In Brazil.
112. Markers of bone destruction and formation and periodontitis in type 1 diabetes mellitus.

     22 July 2009

113. Identification of three wheat globulin genes by screening a Triticum aestivum BAC genomic library with cDNA from a diabetes-associated globulin. Free full text available in PDF format.
114. Progress towards the clinical use of CD3 monoclonal antibodies in the treatment of autoimmunity.
115. Hypoglycemic and beta cell protective andrographolide analogue for diabetes treatment.
116. The glutamic acid decarboxylase 65 immunoglobulin G subclass profile differs between adult-onset type 1 diabetes and latent autoimmune diabetes in adults (LADA) up to 3 years after clinical onset.
117. Mild Fasting Hyperglycemia in a Child: Importance of New Genetic Tools. Also available in PDF format, which includes the referenced tables.
118. Pigment epithelium-derived factor contributes to insulin resistance in obesity. See also Discovery of Link Between Obesity and Type 2 Opens Path to Possible New Treatment and When Weight Is the Issue, Doctors Struggle Too.

     15 July 2009

119. Effect of Ingested Interferon-alpha on beta-Cell Function in Children With New-Onset Type 1 Diabetes.
120. Remission of type 1 diabetes following anti-CD3 antibody treatment and transplantation of embryonic pancreatic precursors.
121. Preservation of Beta Cell Function in Autoantibody Positive Youth with Diabetes.
122. Seasonal variation of diagnosis of Type 1 diabetes mellitus in children worldwide.
123. Maternal Body Mass Index before pregnancy, maternal weight gain during pregnancy, and risk of persistent positivity for multiple diabetes associated autoantibodies in children with the high-risk HLA genotype: The MIDIA study.
124. Glucagon-Like Peptide-1 Functionalized PEG Hydrogels Promote Survival and Function of Encapsulated Pancreatic beta-Cells.
125. Functional Brain Connectivity and Neurocognitive Functioning in Patients with Longstanding Type 1 Diabetes Mellitus with and without Microvascular Complications: a Magnetoencephalography Study.
126. Telomere length and progression of diabetic nephropathy in patients with type 1 diabetes.
127. Study Links Nitrosamines to Mortality in Diabetes, Other Diseases.

     1 July 2009

128. Seeding of pancreatic islets into pre-vascularized tissue-engineering chambers.
129. Inflammation in Diabetic Encephalopathy is Prevented by C-Peptide.

     24 June 2009

130. Australia's national trends in the incidence of Type 1 diabetes in 0-14-year-olds, 2000-2006.
131. Incident Dysglycemia and the Progression to Type 1 Diabetes among Participants in the Diabetes Prevention Trial-Type 1.
132. The effect of glucose variability on the long-term risk of microvascular complications in type 1 diabetes.
133. Safety and Viability of Microencapsulated Human Islets Transplanted Into Diabetic Humans.
134. Familial association between type 1 diabetes and other autoimmune and related diseases.
135. The -174GG interleukin-6 genotype is protective from retinopathy and nephropathy in juvenile onset type 1 diabetes mellitus.

     17 June 2009

136. The Onset of Diabetes in Three out of Four Sisters: A Japanese Family with Type 1 Diabetes. A Case Report. Free full text available in PDF format.
137. Pioglitazone might prevent the progression of slowly progressive type 1 diabetes. Free full text available in PDF format.

     10 June 2009

138. Can childhood viral infection protect from type 1 diabetes?
139. Protective effects of 1-alpha-hydroxyvitamin D3 on residual beta-cell function in patients with adult-onset latent autoimmune diabetes (LADA).
140. Long-term glycemic control influences the long-lasting effect of hyperglycemia on endothelial function in type 1 diabetes.
141. ADA: Fluorescent Intravascular Glucose Sensor Appears Accurate.
142. Genes play role in glycemic control in type 1 diabetes.

     3 June 2009

143. Interplay between PTPN22 C1858T polymorphism and cow's milk formula exposure in type 1 diabetes.
144. Incident Dysglycemia and the Progression to Type 1 Diabetes among Participants in the Diabetes Prevention Trial-Type 1.
145. Incidence trends for childhood type 1 diabetes in Europe during 1989—2003 and predicted new cases 2005—20: a multicentre prospective registration study. See also Type 1 Diabetes Incidence Jumps 4% Annually in Europe's Youngest.
146. Incidence and Time Trend of Type 1 and Type 2 Diabetes in Austrian Children 1999-2007.
147. Prevalence of overweight and obesity in youth with diabetes in USA: the SEARCH for Diabetes in Youth Study.
148. Circulating endothelial progenitor cells, endothelial function, carotid intima-media thickness and circulating markers of endothelial dysfunction in people with type 1 diabetes without macrovascular disease or microalbuminuria.
149. Immunoregulatory mechanisms triggered by viral infections protect from type 1 diabetes in mice. Free full text available in HTML and PDF formats.
150. Changes in autoreactive T cell avidity during type 1 diabetes development.
151. Lifetime prevalence of comorbid mood disorders in a representative sample of Canadians with type 1 diabetes.
152. Accelerated Pharmacokinetics and Glucodynamics of Prandial Insulins Injected With Recombinant Human Hyaluronidase. See also Phase 1 Study For Halozyme's Insulin-PH20 Published, Highlights Findings For Faster Acting Insulin Formulations.
153. Regeneration of the Pancreas in Adult Zebrafish.
154. Predictors of Study Completion and Withdrawal in a Randomized Clinical Trial of a Pediatric Diabetes Adherence Intervention.
155. Influence of Early Nutritional Components on the Development of Murine Autoimmune Diabetes.

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Last Updated: Wed Nov 18 13:39:39 2009
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