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From Urbandale, Iowa, USA:

My daughter is 7 years old and was diagnosed with Type 1 diabetes when she was 4. We changed from Regular insulin to Humalog last year. She also receives NPH. It seems that we had a much harder time controlling her blood sugars (wide variances) with the Humalog. It also seemed than she ran much higher between blood tests when she was given the Humalog. We tried adjusting the Humalog and the NPH and also adjusting snack times and amounts. She also couldn't go without snacks in the A.M. because she would then get way too low before lunch. If we increased the Humalog to compensate for the high mid-morning number, she was very low before lunch. We could never get it adjusted right.

Is it possible that people on Humalog are higher in between meals and they don't realize it? It seems that the Regular works so much better in the in between times (between meals). We have consulted our doctor numerous times and we felt it was better to switch back to Regular. Have other people experienced this same problem with Humalog?


If there were one insulin that suited everybody then there would only be one on the market. Unfortunately, this isn't the case. Many people have found that they have to adjust their snacks, etc. if they change to Humalog. This isn't too surprising since its duration of action and the speed with which it begins to act are so different from soluble (Regular) insulin. Anyone working with children with diabetes will tell you that there are no absolutes and you have to find out what works for you and for your child.


Additional Comments from Linda Mackowiak, diabetes nurse specialist:

You might talk to your diabetes care provider about mixing Regular and Humalog together with the NPH. There was an article in Diabetes Forecast this year which discusses this.


Original posting 18 Jul 1998
Posted to Insulin Analogs


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Last Updated: Tuesday April 06, 2010 15:08:58
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