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From Heidelberg, Gauteng, South Africa:

What could be done to a eleven day old baby girl weighing 4.4 kg at birth if she has hyperinsulinism and hypoglycemia? Blood sugar fluctuates between 1.7 and 7, while given 25% glucose drip and 2 hourly glucagon. Pancreas is not enlarged and no tumors have been detected. What treatment is suggested? Please give long term medication and effects.

Beta cell hyperplasia - Is this disease known to you? Please explain treatment and possible cure in a newborn.


You don't give us enough clinical and lab data to draw any firm conclusion although it is probable that your eleven day old girl could have a transient metabolic deregulation of the pancreatic insulin secretion due to her mother's glucose intolerance or even diabetes during last period of pregnancy as it can be suspected by the baby girl's overweight (macrosomia) at birth. Actually it generally last 2 or 3 days only and then another possibility could be nesidioblastosis of the pancreas (which is very rare). The final solution depends on a rather meticulous medical evaluation.


Original posting 7 Aug 1998
Posted to Hypoglycemia


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Last Updated: Tuesday April 06, 2010 15:08:58
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