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Can you please send any information you have on the effects of long term insulin use for children with diabetes (a 16 year old I know has recently been diagnosed)?


Someone with Type 1 diabetes has no choice but to take insulin every day. Without insulin the body cannot utilise glucose derived from food. With human insulin (derived from genetically modified yeast or chemically from pig insulin) there are no effects to speak of with long term use. With pig or beef insulin antibodies can reach levels which interfere with the action but this simply requires a higher dose.

As a general principle it is fair to say that when naturally occurring substances are given as replacement of a lack rather than in pharmaceutical doses there is unlikely to be harm. Another example would be steroids for people with Addison's disease where they don't make enough of their own.


Original posting 8 Apr 1999
Posted to Insulin


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Last Updated: Tuesday April 06, 2010 15:09:02
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