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From California, USA:

If one is using an insulin pump with Lispro and the insulin supply is terminated, then how long does it take before ketoacidosis is a severe problem?


Probably in about 2 to 3 hours. Lispro insulin [Humalog« brand] only lasts a short while, and there is some delay because of the depot under the skin, but I wouldn't want to have a lack of insulin for than about an hour.

Whenever there is lack of insulin delivery from the pump, you should check blood glucose levels about every 1 - 2 hours to monitor what's going on. That way, you can supplement with an injection if you need to. You should always have a vial of short-acting insulin (Lispro or Regular) and a syringe with you.


Original posting 30 Jun 1999
Posted to Insulin Pumps and Hyperglycemia and DKA


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Last Updated: Tuesday April 06, 2010 15:09:06
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