Back to Ask the Diabetes Team Ask the Diabetes Team

From Pennsylvania:

My 10 year old son, who was diagnosed five years ago and has been pumping for three years, recently had a 24 hour urine test done. His A1c has always been between 7 and 8. He is active in a number of different sports. I'm not sure if I should be worried about the results and discuss them with his endocrinologist or not. I was hoping you could provide me with some direction. The results were as follows:

  • 24 hour creatinine = 1.11 (range.6 - 2.0)
  • Creatinine clearance = 169 (range 72 - 137)
  • 24 hour protein = 126 (range 50 - 100)

Is this the beginning of kidney problems? His endocrinologist is contemplating beginning him on an ACE inhibitor. What are the long term effects of taking such a medication?


I wonder if the urine was not collected properly. We usually do overnight and not 24 hour collections because of such commonly seen timing problems. Also, the key test is not 24 hour protein but 24 hour microalbumin since the microalbumin represents a very sensitive early assay for urinary protein losses while the standard protein assay is very insensitive in the lower ranges when such leakage is showing up. We usually repeat the overnight urine sample or the 24 hour urine sample several times before starting medication because the test is so difficult to do and interpret properly. So, please go back and discuss with the diabetes team.


Original posting 9 Mar 2004
Posted to Complications


  Back to Ask the Diabetes Team Return to the Top of This Page

Last Updated: Tuesday April 06, 2010 15:09:56
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.

This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents. Our mission is to provide education and support to families living with type 1 diabetes.
By using this site, you agree to our Terms of Use, Legal Notice, and Privacy Policy.
© Children with Diabetes, Inc. 1995-2018. Comments and Feedback.