Back to Ask the Diabetes Team Ask the Diabetes Team

From Catonsville, Maryland, USA:

I was just forwarded an e-mail regarding a little girl whom had gone off the pump. She went from a type 1 to a type 2 diabetic using a sulfonylurea. It stated she had a gene called Kir6.2, which mutates due to the drug to produce insulin. Do you have any information regarding any studies? Is this e-mail a hoax?


The information you read is correct.

In the August 3, 2006 issue of The New England Journal of Medicine, researchers reported that patients with a rare form of neonatal diabetes can be treated more effectively and more safely using sulfonylurea medication instead of insulin. For these patients, this is an incredible breakthrough in treatment.

For more information see Switching from Insulin to Oral Sulfonylureas in Patients with Diabetes Due to Kir6.2 Mutations and Activating Mutations in the ABCC8 Gene in Neonatal Diabetes Mellitus.


Original posting 18 Sep 2006
Posted to Research: Other Research


  Back to Ask the Diabetes Team Return to the Top of This Page

Last Updated: Tuesday April 06, 2010 15:10:08
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.

This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents. Our mission is to provide education and support to families living with type 1 diabetes.
By using this site, you agree to our Terms of Use, Legal Notice, and Privacy Policy.
© Children with Diabetes, Inc. 1995-2018. Comments and Feedback.