Back to Ask the Diabetes Team Ask the Diabetes Team

From Ames, Iowa, USA:

Recently, my two-year-old and I took a part of TrialNet study (The Natural History Study of the Development of Type 1 Diabetes). Both results were negative. I have asked them to provide more accurate data about the antibodies to know the real value. If the antibody test was negative, what does it mean? Does it mean that type 1 will never happen or does it mean it can happen at any time, even with a very negative test? What are the limits for negative and negative tests?


They should answer such questions more specifically for you. In fact, you probably already have such information in what you originally received from them. In general, the antibody tests sometimes convert from negative to positive. The more positive, the higher the titers, the more likely that these are "real" abnormalities and will persists. But, sometimes, even high values are transient. More than one antibody positive and higher titers for several mean more likely ongoing inflammatory changes are real, will persist, and therefore more risk for developing frank diabetes. Also, there are many people who are antibody negative since the tests are not 100% and stay negative.


Original posting 7 Feb 2007
Posted to Other


  Back to Ask the Diabetes Team Return to the Top of This Page

Last Updated: Tuesday April 06, 2010 15:10:10
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.

This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents. Our mission is to provide education and support to families living with type 1 diabetes.
By using this site, you agree to our Terms of Use, Legal Notice, and Privacy Policy.
© Children with Diabetes, Inc. 1995-2018. Comments and Feedback.