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From Spartanburg, South Carolina, USA:

Just because you have a normal C-Peptide level, does that mean you don't have type 1 diabetes even though you have positive antibodies, hypothyroidism, and a strong family history of diabetes? Is it possible for your body to produce C-Peptide, but it doesn't work and makes the test be normal?


C-Peptide is a marker of insulin secretion in the body. For every molecule of C-Peptide secreted, a molecule of insulin is secreted. Early in diabetes (loosely referring to the first few years), you may have measurable C-Peptide levels but still have type 1 diabetes. The thought is that over time, the autoimmune process that killed off the initial insulin-producing cells will do the same for the remaining cells. Therefore, you would see a gradual fall off in the C-Peptide level over time. However, it is not bad to have C-Peptide. In those patients who have some C-Peptide still secreted, it is probably easier to control blood sugars because you can still make some insulin on your own. Type 1 diabetes is less prone to have a marked family history than type 2 diabetes. Hypothyroidism tends to be more common in patients with type 1 diabetes as both are diseases that involve overactivity of the body's immune system and often cluster together in the same patient.


Original posting 16 Jun 2007
Posted to Diagnosis and Symptoms


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Last Updated: Tuesday April 06, 2010 15:10:12
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