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Research News From 1997

  1. MiniMed Inc. Submits FDA Notification On Continuous Glucose Sensor For Diabetes. (28 Dec 97)
  2. Reduced Frequency of Severe Hypoglycemia and Coma in Well-Controlled IDDM Patients Treated With Insulin Lispro, an article in the December 1997 issue of Diabetes Care, concludes that, in well-controlled patients with Type 1 diabetes, use of insulin lispro is associated with a lower risk of severe hypoglycemia and coma. (20 Dec 97)
  3. Long-Term Function (6 Years) of Islet Allografts in Type 1 Diabetes, in the December 1997 issue of Diabetes, summarizes the results of islet cell transplants in eight patients with Type 1 diabetes. (20 Dec 97)
  4. The authors of Prevention of Type 1 Diabetes, published in the November 1997 issue of Diabetes Spectrum, believe that Type 1 diabetes will "eventually eradicated through modification of environmental factors." (20 Dec 97)
  5. Long-Term Function (6 Years) of Islet Allografts in Type 1 Diabetes, in the December 1997 issue of Diabetes, summarizes the results of islet cell transplants in eight patients with Type 1 diabetes. (20 Dec 97)
  6. Glucose Metabolism Defect In Rare Form Of Diabetes Revealed. (14 Dec 97)
  7. Cygnus, Inc. announced the results from a series of research clinical studies conducted in 1997 for its GlucoWatch non-invasive glucose monitor. (30 Nov 97)
  8. Insulin Pens And Cartridges May Be Safely Interchanged. (30 Nov 97)
  9. Gender Differences in Hospitalizations for IDDM Among Adolescents in California, 1991, the November 1997 issue of Diabetes Care, reports on a study that showed that teenage girls with diabetes experience significantly more hospital admissions related to their diabetes than do teenage boys, highlighting the need to address the underlying causes in treatment plans. (9 Nov 97)
  10. So What's the Difference Between Teenage Boys and Girls, Anyway?, an editorial by Dr. Stuart Brink published in the November 1997 issue of Diabetes Care, reflects on the report about increased hospitalizations of teenage girls with diabetes and highlights what might be some of the underlying causes. (9 Nov 97)
  11. Aspirin Therapy in Diabetes presents the official American Diabetes Association position on the use of aspirin by diabetics as part of an overall strategy to reduce the risk of cardiovascular disease. (9 Nov 97)
  12. Diabetes at highest levels ever in the U.S., according to news reports. (2 Nov 97)
  13. Dr. Camillo Ricordi, Scientific Director of the Diabetes Research Institute (DRI) at the University of Miami, responds to a message posted at the Islet Foundation web site regarding a letter he sent to Dr. Usala at Encelle, a corporation involved in islet cell transplant research. (12 Oct 97)
  14. On October 2, 1997, The New England Journal of Medicine published a letter to the editor about possible adverse fetal effect of insulin lispro and a reply by a spokesperson for Lilly Research Laboratories. This letter was based upon two pregnancies with problems, neither of which can be clearly ascribed to lispro insulin [Humalog® brand]. We publish this hyperlink because it is important for our readers to know that there are cases of diabetic women with excellent glycohemoglobin values who may have problems with their pregnancies. Whether these problems are due to the lispro, or to other causes, is unknown. (We have also answered a question from a reader about this problem.)
  15. Researchers report on gene mutation associated with rare form of diabetes.
  16. Earlier in 1997, VivoRx received approval for Phase One clinical trials of xenotransplantation of encapsulated porcine islets for the treatment of Type 1 diabetes in people who are already receiving immunosuppressant drugs (most likely due to a kidney transplant). Read the Fact Sheet on Xenotransplantation from the U.S. Food and Drug Administration outlines the U.S. Government guidelines for transplantation using animal sources, and the story of Steven Craig, first recipeint of encapsulated islets who was able to stop taking insulin injections. (28 Sep 97)
  17. Prediction of Type 1 Diabetes Postpartum in Patients With Gestational Diabetes Mellitus, from the September 1997 issue of Diabetes, reports that the presence of beta cell autoantibodies after delivery are "highly predictive for the development of type 1 diabetes postpartum." (28 Sep 97)
  18. HbA1c level correlates with risk of complications, according to a University of Pittsburgh study published in the Archives of Internal Medicine. (14 Sep 97)
  19. Stillbirths, malformations in children of diabetic mothers could be prevented, according to a study published in the British Medical Journal. (14 Sep 97)
  20. Results Confirm Proof of Concept for Amylin Replacement Therapy.
  21. New therapy may prevent rejection of transplanted organs reports on a new technique for eliminating graft rejection without the use of immunosuppressant drugs. (10 Aug 97)
  22. IDDM, Counterregulation, and the Brain addresses the question, "Does the brain of a person with IDDM respond to hypoglycemia differently than the brain of someone without diabetes?" (2 Aug 97)
  23. IDDM and Milk Consumption, a study conducted in Brazil, concludes that shorter duration breast feeding increases risk for Type 1 diabetes, and that exposure to cow's milk before eight days of age increases risk for Type 1 diabetes. (2 Aug 97)
  24. Preservation of Physiological Responses to Hypoglycemia 2 Days After Antecedent Hypoglycemia in Patients With IDDM reports on the effects of hypoglycemia on the body's response to additional hypoglycemia several days later. This research explores a possible explanation for the cause of hypoglycemia unawareness. (2 Aug 97)
  25. Alanine and Terbutaline in the Prevention of Nocturnal Hypoglycemia in IDDM reports on a study that examined "whether bedtime administration of the glucagon-releasing amino acid alanine or the epinephrine-simulating ß2-adrenergic agonist terbutaline more effectively prevents nocturnal hypoglycemia than a conventional bedtime snack." (2 Aug 97)
  26. As reported in the journal Science, scientists from Washington University in St. Louis and Eli Lilly & Company found that large doses of C-peptide, injected with insulin, repaired blood vessels and nerves that had been damaged by diabetes in rats. If additional research confirms these results, people with diabetes might be able to loosen their control goals without increasing their risk of complications. This would help reduce the risk of hypoglycemia that accompanies tight control. For additional information, see Insulin byproduct might help diabetics from CNN Interactive. (27 Jul 97)
  27. Type 1 Women Often Develop Lumps in Breasts. From
  28. World suffering diabetes epidemic, conference told. From CNN Interactive. (27 Jul 97)
  29. Dietary Cow's Milk Protein Does Not Alter the Frequency of Diabetes in the BB Rat. (July 1997 issue of Diabetes.)
  30. A new method of extracting islets from donor pancreases yields improved results over previous methods. (Reported in the July 1997 issue of Diabetes.)
  31. Research into the Reliability of Current Guidelines for Recreational Scuba Divers with Insulin-Dependent Diabetes, reported in Diabetes Monitor, describes a research project to study scuba diving by people with Type 1 diabetes. (20 Jul 97)
  32. You can search the abstracts of material presented at the 57th Annual American Diabetes Association Meeting at the 57th Scientific Sessions Abstract Search page. (6 Jul 97)
  33. Hypoglycemia: Incidence and Clinical Predictors in a Large Population-Based Sample of Children and Adolescents With IDDM, from the January 1997 issue of Diabetes Care, concludes that younger children are at a particular risk of significant hypoglycemia. (6 Jul 97)
  34. In addition to our earlier report that BCG Vaccination Given After Onset of Type 1 Diabetes Not Helpful, there is another report entitled Vaccination with BCG at Diagnosis Does Not Alter the Course of IDDM. (6 Jul 97)
  35. Cloning and Sequencing of the Pancreatic Islet Neogenesis Associated Protein (INGAP) Gene and Its Expression in Islet Neogenesis in Hamsters describes some exciting research. (15 Jun 97)
  36. KU Researcher Reports on Promising Diabetes Monitor reports on an implantable glucose monitor. (15 Jun 97)
  37. Experimental gene therapy offers hope to diabetics briefly summarizes research into islet cell regeneration. Be sure to read a related Diabetes Team question & answer. (4 May 97)
  38. Assessing, Controlling, and Assuring the Quality of Medical Information on the Internet is an editorial by the Journal of the American Medical Association.
  39. Diabetes Institutes researchers isolate gene, protein involved in pancreatic islet regeneration. (19 Apr 97)
  40. In an editorial entitled Islet and Pancreatic Transplantation -- Autoimmunity and Alloimmunity, Drs. George S. Eisenbarth and Mark Stegall of the Barbara Davis Center for Childhood Diabetes discuss the limits to the success of pancreatic transplants. (19 Apr 97)
  41. MATECH Biomedical Technologies has been awarded a grant by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH). The grant is titled Ceramic gel Encapsulation of Islets for Treating Diabetes. Diabetic lab mice have been successfully treated for up to 3 months, showing no sign of diabetes. Further research is aimed at extending the treatment to one year. (Related question to the Diabetes Team) (13 Apr 97)
  42. Acarbose in the Treatment of Type 1 Diabetes (30 Mar 97)
  43. Effect of Intensive Treatment of Diabetes on the Risk of Death or Renal Failure in NIDDM and IDDM (30 Mar 97)
  44. Biocontrol Demonstrates the Diasensor 1000 for the Press. (18 Feb 97)
  45. Biocontrol Technology, Inc. to begin an in-home study of the Diasensor 1000 noninvasive glucose sensor. (25 Jan 97)

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