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Research News From 1999

  1. Presentations from the 1999 European Association for the Study of Diabetes are available at Medscape, including Recent Progress in Insulin Therapy, Advanced Technology in Diabetes Management, New Developments in the Treatment of Type-2 Diabetes: Implications for Children and Adolescents, and Psychosocial Aspects of Type 1 Diabetes Mellitus. (Free Medscape membership required) (26 December 1999)
  2. Incyte and Cambridge University Scientists Identify a New Genetic Cause for Type 2 Diabetes, Severe Insulin Resistance and Early Hypertension. (26 December 1999)
  3. Study reports on results after lens extraction in patients with diabetic retinopathy. (26 December 1999)
  4. Cellular Phones Compatible With Insulin Pumps. (19 December 1999)
  5. Inhale Issued Patent on Inhaleable Insulin. (19 December 1999)
  6. Artificial Pancreas for Diabetics Not Many Years Off, Scientists Say. (19 December 1999)
  7. Study reports on clinical, autoimmune, and genetic characteristics of very young children with type 1 diabetes. (12 December 1999)
  8. Transcutaneous Glucose Measurement Using Near-Infrared Spectroscopy During Hypoglycemia reports on a new method of non-invasive glucose sensing. (12 December 1999)
  9. Counseling Techniques for Clinicians and Educators contrasts the outcomes of two approaches to clinic-based, diabetes-related interviewing and counseling. (12 December 1999)
  10. Psychological Complications of Childhood Diabetes: Case Examples discusses three common barriers to healthy coping with childhood diabetes. (12 December 1999)
  11. Progression to Diabetes in Relatives with Islet Autoantibodies. (5 December 1999)
  12. Study reports that visual complications of diabetes are predictive of mortality. (28 November 1999)
  13. Comparison of the effect of alpha-lipoic acid and alpha-tocopherol supplementation on measures of oxidative stress. (28 November 1999)
  14. Alpha-Lipoic acid decreases oxidative stress even in diabetic patients with poor glycemic control and albuminuria. (28 November 1999)
  15. JDF funds Center for Human Islet Transplantation in Seattle, Washington. (28 November 1999)
  16. In vivo glucose sensing for diabetes management: progress towards non-invasive monitoring explains recent advances in technology that are being applied to blood glucose sensing. (21 November 1999)
  17. Smudge on skin may be early sign of Type 2 diabetes in kids. (21 November 1999)
  18. Immediate intensive therapy upon diagnosis preserves residual beta cell function. (11 November 1999)
  19. Amylin Pharmaceuticals Reports Positive Results for SYMLIN in US Type 1 Diabetes Study. (11 November 1999)
  20. We review recent claims and research regarding immunizations and Type 1 diabetes. (6 November 1999)
  21. Research team needs new onset cases to test immunusuppressant drug. (30 October 1999)
  22. Correlation of fingerstick blood glucose measurements with GlucoWatch biographer glucose results in young subjects with type 1 diabetes. (30 October 1999)
  23. In a letter to the Editor of the British Medical Journal, Bart Classen reiterates his claim that there is an association between type 1 diabetes and Hib vaccine. (30 October 1999)
  24. Biogen halts research using anti-CD40 ligand, also called anti-CD154. (24 October 1999)
  25. Study reports that mortality rates are excessive for children with Type 1 diabetes, mostly due to DKA. (24 October 1999)
  26. Genetically Modified Hepatocytes Produce And Secrete Human Insulin. (24 October 1999)
  27. Study reports on thyroid autoimmunity in children and adolescents with Type 1 diabetes mellitus. (24 October 1999)
  28. Type 2 Diabetes Is Growing Problem in Children and Teens. See also Type 2 Diabetes in Children -- Concerns About a Growing Threat. (Free Medscape membership required) (24 October 1999)
  29. In spite of Hurricane Irene, the Diabetes Research Institute offered a World of Hope. (17 October 1999)
  30. JDF announces five year, $7.5 million grant to establish the JDF Center for Islet Transplantation at the University of Chicago and University of Minnesota. (10 October 1999)
  31. Diabetes Prevention Trial-Type 1 Is Short of Its Enrollment Goals. (10 October 1999)
  32. The temporal development of retinopathy and nephropathy in type 1 diabetes mellitus during 15 years diabetes duration examined the 10- and 15-year incidence and course of retinopathy in 29 adults with Type 1 diabetes. (10 October 1999)
  33. Study reports on seasonality of birth in children with diabetes in Europe. (10 October 1999)
  34. New technique may help treat diabetes, according to researcher at the Ohio State University. See New Technique Builds Microscopic Medical Devices For Transplants for more details. (3 October 1999)
  35. Myriad Genetics Discovers Diabetes Gene. See also Potential Cause for Diabetes. (26 September 1999)
  36. Study examined microalbuminuria and relationship to duration of diabetes, sex, and metabolic control. (19 September 1999)
  37. Study reports on long-term effectiveness of pancreas transplants. (19 September 1999)
  38. Study examined change in the neuropsychological profiles of children with type 1 diabetes 2 years after disease onset. (19 September 1999)
  39. Study concludes that poor metabolic control influences the increased rate of bone resorption in children with diabetes. (19 September 1999)
  40. Study reports on causes of death in children and young adults in the UK with Type 1 diabetes.
  41. Is undetected autonomic dysfunction responsible for sudden death in Type 1 diabetes mellitus? (12 September 1999)
  42. Prospective Human Trial Implicates Cow's Milk in Type 1 Diabetes. (5 September 1999)
  43. Results of Yale Diabetes Study Could Lead to Use of Insulin in Preventative Therapy. You can also read the full text of the study. (5 September 1999)
  44. Prevention of Type 1 Diabetes Mellitus reviews prevention trials underway around the world. (29 August 1999)
  45. Studys shows that older adults with Type 1 diabetes have lower bone mineral density than adults with Type 2 diabetes or without diabetes. (29 August 1999)
  46. A study on Retinopathy in diabetic patients aged 15-50 years in the county of Umea, Sweden showed that duration of diabetes, proteinuria, glycosylated hemoglobin and male gender were statistically associated with severeness of retinopathy. (29 August 1999)
  47. New procedure offers diabetics freedom explores islet cell transplants. (22 August 1999)
  48. In conjunction with a report on Clinical Features of 52 Neonates with Hyperinsulinism, The New England Journal of Medicine published an editorial on The Causes of Neonatal Hypoglycemia. (22 August 1999)
  49. Study reports on neurocognitive functioning in children diagnosed with diabetes before age 10 years. (22 August 1999)
  50. Genetic determination of islet cell autoimmunity in monozygotic twin, dizygotic twin, and non-twin siblings of patients with type 1 diabetes reports on a study done at the Barbara Davis Center which suggests that genetic factors play an important part in determination of islet cell autoimmunity. (22 August 1999)
  51. Diabetic Polyneuropathy, by Stuart C. Apfel, MD, defines "state-of-the art" treatment protocols and clinical strategies for the prevention and management of diabetic polyneuropathy. (22 August 1999)
  52. Only multiple autoantibodies to islet cells (ICA), insulin, GAD65, IA-2 and IA-2beta predict immune-mediated (Type 1) diabetes in relatives. (22 August 1999)
  53. British Researchers Say Closer To Diabetes Cure. (22 August 1999)
  54. Study Finds No Infection From Pig Transplants. (22 August 1999)
  55. German BABYDIAB study finds early expression and high prevalence of islet autoantibodies for DR3/4 heterozygous and DR4/4 homozygous offspring of parents with Type I diabetes. (15 August 1999)
  56. Perinatal and neonatal determinants of childhood type 1 diabetes showed that neonatal illnesses increased and initial breast feeding decreased the risk of childhood type 1 diabetes. (15 August 1999)
  57. Month of Birth Affects Risk of Childhood-Onset Diabetes. (Free Registration Required) (15 August 1999)
  58. Maturity-onset diabetes of the young (MODY): a new challenge for pediatric diabetologists. (15 August 1999)
  59. Eating disorders in adolescents with type 1 diabetes mellitus summarizes a study which reports that 10% of young women with Type 1 diabetes can be diagnosed with an eating disorder. (8 August 1999)
  60. Conventional Versus Intensive Diabetes Therapy in Children with Type 1 Diabetes documents cognitive impairments due to hypoglycemia from intensive therapy. (25 July 1999)
  61. High-Dose Vitamin E Supplementation Normalizes Retinal Blood Flow and Creatinine Clearance in Patients with Type 1 Diabetes. (25 July 1999)
  62. Counterregulation during spontaneous nocturnal hypoglycemia in prepubertal children with type 1 diabetes concludes that the risk of nighttime hypoglycemia must be reduced before children with diabetes receive intensive insulin therapy. (25 July 1999)
  63. Partial remission phase of diabetes in children younger than age 10 years reports on a recent study of the honeymoon period in young children. (18 July 1999)
  64. Karlsburg Type I diabetes risk study of a general population: frequencies and interactions of the four major Type I diabetes-associated autoantibodies studied in 9419 schoolchildren. (18 July 1999)
  65. "Silent Diabetes": A Hidden Stage Of Type 1? is from the June 1999 issue of Diabetes Forecast. (4 July 1999)
  66. Science News Online reports on a Finnish study, reported at the 1999 ADA Scientific Sessions, linking cow's milk to increased risk of Type 1 diabetes. (4 July 1999)
  67. Use of Insulin Pump Therapy at Night Only for Pre-Teen Children with Type 1 Diabetes. (3 July 1999)
  68. Study Examines Intensive Therapy and Children (3 July 1999)
  69. The Xenotransplantation Subcommittee of the US Food and Drug Administration met on June 3-4 1999 in Bethesda, Maryland to seek expert and public input into the creation of a regulatory framework. There is a brief report on that meeting at The Islet Foundation. (20 June 1999)
  70. Dr. Camillo Ricordi addresses questions about anti-CD40L/anti-CL154 posted at the Islet Foundation message board. (13 June 1999)
  71. Watch a video report about Experimental Drug Therapy Could Help Treat Diabetes In Humans performed at the Diabetes Research Institute in Miami, Florida. (RealMedia player requried) (13 June 1999)
  72. Scientific American reports on research which shows that turning off a single gene protects mice against obesity and Type 2 diabetes. (13 June 1999)
  73. Alteon releases results of Phase I human trials of drug to limit the damage caused by Advanced Glycosylation End-products. (See A.G.E. Backgrounder for a primer on AGEs.) (6 June 1999)
  74. Research Focuses Worldwide Attention On Diamyd Diabetes Vaccine. (30 May 1999)
  75. A study suggests that a specific HLA allele confers protection from developing Type 1 diabetes even in the presence of islet cell antibodies. (30 May 1999)
  76. A recent study reports that children with Type 1 diabetes who suffer hypoglycemic seizures showed deficits on perceptual, motor, memory, and attention tasks. (30 May 1999)
  77. A recent study highlights the importance of testing siblings of children with Type 1 diabetes for early indications of the disease. (30 May 1999)
  78. New Group Pushes For Controversial Cell Research. (30 May 1999)
  79. JDF Awards $10 Million to Fund Islet Cell Transplantation. (23 May 1999)
  80. Study shows that though tight control is achievable in children with Type 1 diabetes, due to the risk of hypoglycemia, children under the age of 5 should have a higher pre-meal blood sugar target. (23 May 1999)
  81. Study finds serum advanced glycation end products (S-AGEs) may be elevated even in preschool and prepubertal children with diabetes, infering that the risk of microvascular complications may be present at an early age. (23 May 1999)
  82. Study shows that carbohydrate counting works regardless of amount of carbohyrdate eaten. (16 May 1999)
  83. GAD Protein may be key to Type 1 diabetes. (14 May 1999)
  84. A new kind of inhaled insulin was in the news last week. Previous inhaled insulin tests involved a dry powder. (9 May 1999)
  85. Fungus found to have insulin-like effects. (9 May 1999)
  86. Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: the 2-year analysis of the German BABYDIAB Study. (9 May 1999)
  87. Advanced glycation end products in children and adolescents with diabetes: relation to glycemic control and early microvascular complications [J Pediatr 1999 Apr;134(4):486-91] concludes that the risk of microvascular complications may be present at an early age. (9 May 1999)
  88. Cow's milk and type I diabetes: the gut immune system deserves attention (Immunology Today 1999, 20:108-110), raises new concerns about cow's milk. (Free registration with required.) (2 May 1999)
  89. Drug May Cut Diabetes Linked To Ovarian Cysts. (2 May 1999)
  90. Chromium Picolinate May Be Cancer Risk, according to a story published in the Diabetes Mall. (2 May 1999)
  91. Reversal of naturally occuring diabetes in primates by unmodified islet xenografts without chronic immunosuppression. (24 April 1999)
  92. Transplantation of islets using microencapsulation: studies in diabetic rodents and dogs. (24 April 1999)
  93. Patients diagnosed with Type 1 after age 30 have a high risk for heart disease if their blood sugar control is poor, according to a report in the April 199 issue of the journal Arteriosclerosis, Thrombosis and Vascular Biology. (18 April 1999)
  94. Heart disease remains a major cause of death for people with diabetes, according to a recent study published in the Journal of the American Medical Association. (18 April 1999)
  95. The April 1999 issue of Scientific American has an excellent article about creating semisynthetic, living organs that can be used as human replacement parts. (11 April 1999)
  96. Diabetes of the old and slow is now a worry for children, reports the Philadelphia Enquirer. (4 April 1999)
  97. Clinical trial of a new immunosuppresive agent to treat new onset Type 1 diabetes mellitus. (3 April 1999)
  98. The Division of Digestive Diseases and Nutrition of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is preparing to fund a study on the prevelance of celiac disease in the US. (28 March 1999)
  99. Implications of the United Kingdom Prospective Diabetes Study provides the position statement of the American Diabetes Association. (21 March 1999)
  100. Study shows that obese black teens at greater risk for Type 2 diabetes than obese white teens. (14 March 1999)
  101. Scientists discover genetic clues to Type 2 diabetes. (7 March 1999)
  102. Study hints that vitamin D supplementation was associated with a decreased risk of Type 1 diabetes. [Diabetologia (1999) 42: 51-54] (21 February 1999)
  103. A study found an increased frequency of cord blood islet autoantibodies in kids who later developed Type 1 diabetes, suggesting that the Type 1 diabetes process could already be initiated in utero. [Diabetologia (1999) 42: 181-187] (21 February 1999)
  104. Autoantibodies associated with Type 1 diabetes mellitus persist after diagnosis in children. [Diabetologia (1998) 41: 1293-1297] (21 February 1999)
  105. Novo Nordisk Donates $16 Million to Find Cause of Diabetes Complications. (5 February 1999)
  106. Al Gordon, President of The Islet Foundation, testified before the Canadian Parliment about xenotransplantation. (5 February 1999)
  107. Antioxidants may protect against Type 2 diabetes, according to research published in the January 15, 1999 edition American Journal of Epidemiology. (31 January 1999)
  108. Amylin Pharmaceuticals Announces Additional Data From Long-Term Pramlintide Studies. (31 January 1999)
  109. Amylin Pharmaceuticals Announces Mid-2000 Pramlintide Regulatory Filing Strategy and New Clinical Data from Completed Phase 3 Trials. (17 January 1999)
  110. Gabapentin proves effective in treating neuropathy in patients with diabetes mellitus. (2 January 1999)

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