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Research News From 2008

    31 December 2008

  1. Lentivectors encoding immunosuppressive proteins genetically engineer pancreatic beta-cells to correct diabetes in allogeneic mice.
  2. A multi-year analysis of islet transplantation compared with intensive medical therapy on progression of complications in type 1 diabetes.
  3. Islet transplantation with alemtuzumab induction and calcineurin-free maintenance immunosuppression results in improved short- and long-term outcomes.
  4. Current status of islet cell transplantation.
  5. Islet cell transplantation for the treatment of type 1 diabetes in the USA.
  6. Accumulation of autoreactive effector T cells and allo-specific regulatory T cells in the pancreas allograft of a type 1 diabetic recipient.

    24 December 2008

  7. Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes. See also Breakthrough In Understanding Development Of Type 1 Diabetes
  8. Longitudinal observation of parechovirus in stool samples from Norwegian infants. See also Common infant virus may trigger type 1 diabetes.
  9. Type 1 diabetes, the A1 milk hypothesis and vitamin D deficiency.
  10. Impact of Lifestyle and Dietary Habits on Hypovitaminosis D in Type 1 Diabetes Mellitus and Healthy Children from Qatar, a Sun-Rich Country.
  11. Retinal vessel response to flicker light in children and adolescents with type 1 diabetes mellitus and overweight or obesity.
  12. Evaluation of quality of life after simultaneous pancreas and kidney transplantation from living donors using short form 36.
  13. Hyperglycaemia is associated with changes in the regional concentrations of glucose and myo-inositol within the brain.
  14. Production of beta-cells from human embryonic stem cells.
  15. Can beta-cells be derived from exocrine pancreas?

    17 December 2008

  16. The "Metabolic Memory": Is More than Just Tight Glucose Control Necessary to Prevent Diabetic Complications? Free full text available in PDF format.
  17. Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes. See also VTT - New scientific knowledge on juvenile diabetes: Metabolic disturbances indicate progress of the disease even years in advance.
  18. Poorly controlled type 1 diabetes is associated with altered glutathione homeostasis in adolescents: apparent resistance to N-acetylcysteine supplementation.
  19. Long-term trends in the incidence of type 1 diabetes in Denmark: the seasonal variation changes over time.
  20. Subcutaneous transplantation of embryonic pancreas for correction of type 1 diabetes.
  21. A Novel Non-invasive Breath Test Method For Screening Persons At Risk For Diabetes.

    10 December 2008

  22. Effects of a controlled hypoglycaemia test on QTc in adolescents with Type 1 diabetes.
  23. Association between reduced pulmonary diffusing capacity and cardiac autonomic dysfunction in Type 1 diabetes.
  24. Induction of innate immune response through TLR2 and dectin 1 prevents type 1 diabetes.
  25. Autologous bone marrow-derived rat mesenchymal stem cells promote PDX-1 and insulin expression in the islets, alter T cell cytokine pattern and preserve regulatory T cells in the periphery and induce sustained normoglycemia.
  26. High-dose thiamine therapy for patients with type 2 diabetes and microalbuminuria: a randomised, double-blind placebo-controlled pilot study. See also Vitamin B1 could reverse early-stage kidney disease in diabetes patients.
  27. Dipeptidyl Peptidase IV Inhibition with MK0431 Improves Islet Graft Survival in Diabetic NOD Mice Partially via T-cell Modulation.
  28. Phenotypic Type 2 Diabetes in Obese Youth: Insulin Sensitivity and Secretion in Islet-cell Antibody Negative vs. Antibody Positive Patients.
  29. Antecedent hypoglycemia impairs autonomic cardiovascular function - implications for rigorous glycemic control.
  30. Hypertriglyceridaemia is associated with an increased likelihood of albuminuria in extreme duration (> 50 years) Type 1 diabetes.

    3 December 2008

  31. Proinsulin peptide immunotherapy in type 1 diabetes: report of a first-in-man Phase I safety study.
  32. In vivo characterization of transplanted human embryonic stem cell-derived pancreatic endocrine islet cells.
  33. Cognitive dysfunction and hippocampal changes in experimental type 1 diabetes.

    26 November 2008

  34. Differences in prevalence of antibodies to GAD and IA-2 and their titers at diagnosis in children with slowly and rapidly progressive forms of type 1 diabetes.
  35. Endocrine autoimmunity in families with type 1 diabetes: frequent appearance of thyroid autoimmunity during late childhood and adolescence.
  36. Impaired Hyperglycemia-Induced Delay in Gastric Emptying in Patients With Type 1 Diabetes Deficient for Islet Amyloid Polypeptide.
  37. Iodine and tri-iodo-thyronine reduce the incidence of type 1 diabetes mellitus in the autoimmune prone BB rats.

    19 November 2008

  38. Fasting plasma C-peptide and micro- and macrovascular complications in a large clinic-based cohort of type 1 diabetic people.
  39. Exenatide Sensitizes Insulin-mediated Whole-body Glucose Disposal and Promotes Uptake of Exogenous Glucose by the Liver.
  40. Influence of cardiovascular autonomic neuropathy on atherogenesis and heart function in patients with Type 1 diabetes.
  41. Recovery of endogenous beta cell function in non-human primates following chemical diabetes induction and islet transplantation.
  42. Tyrosine kinase inhibitors reverse type 1 diabetes in nonobese diabetic mice. See also Two cancer drugs prevent, reverse type 1 diabetes, UCSF study shows.
  43. Mitomycin C-treated dendritic cells inactivate autoreactive T cells: Toward the development of a tolerogenic vaccine in autoimmune diseases. Free full text available in PDF format.
  44. Egg Consumption and Risk of Type 2 Diabetes in Men and Women.

    12 November 2008

  45. Completely Novel Action Of Insulin Unveiled. The scientific paper is CaMKII-Mediated Phosphorylation of the Myosin Motor Myo1c Is Required for Insulin-Stimulated GLUT4 Translocation in Adipocytes.
  46. A 10-year (1996-2005) prospective study of the incidence of Type 1 diabetes in Moscow in the age group 0-14 years.
  47. Vitamin D and diabetic nephropathy.
  48. Evaluation of adiponectin level in children and adolescents with diabetes type 1.
  49. Distinct autoantibodies against exocrine pancreatic antigens in European patients with type 1 diabetes mellitus and non-alcoholic chronic pancreatitis.
  50. The influence of diabetes mellitus type 1 and 2 on the thickness, shape, and equivalent refractive index of the human crystalline lens.

    5 November 2008

  51. Effects of oral consumption of the green tea polyphenol EGCG in a murine model for human Sjogren's syndrome, an autoimmune disease. See also Green tea may delay onset of type 1 diabetes.
  52. Childhood type 1 diabetes in Iceland; Evaluation of quality of treatment.
  53. Pitfalls in the measurement of the nocturnal blood pressure dip in adolescents with type 1 diabetes.
  54. Treatment of Experimental Periodontal Disease by Photodynamic Therapy in Rats With Diabetes.

    29 October 2008

  55. Glucose and C-Peptide Changes in the Perionset Period of Type 1 Diabetes in the Diabetes Prevention Trial–Type 1.
  56. Role of coxsackievirus B4 in the pathogenesis of type 1 diabetes.
  57. The growing incidence of type 1 diabetes in children: The 17-year French experience in Aquitaine.
  58. Lessons learned from studies of the natural history of diabetic nephropathy in young type 1 diabetic patients.
  59. Oxidative stress as a common mediator for apoptosis induced-cardiac damage in diabetic rats. Free full text available in HTML and PDF formats.
  60. Experimental microencapsulation of porcine and rat pancreatic islet cells with air-driven droplet generator and alginate.

    22 October 2008

  61. Kinetics of Insulin Secretion from MIN6 Pseudoislets after Encapsulation in a Prototype Device of a Bioartificial Pancreas.
  62. Relationship between beta-cell mass and diabetes onset.
  63. A new model defines the minimal set of polymorphism in HLA-DQ and -DR that determines susceptibility and resistance to autoimmune diabetes. Free full text available in PDF format.
  64. Orally administered microencapsulated lysozyme downregulates serum AGE and reduces the severity of early-stage diabetic nephropathy.
  65. Serum endogenous secretory RAGE level is an independent risk factor for the progression of carotid atherosclerosis in type 1 diabetes.

    15 October 2008

  66. GAD Treatment and Insulin Secretion in Recent-Onset Type 1 Diabetes. Free full text available in HTML and PDF formats. Immunotherapy on Trial for New-Onset Type 1 Diabetes (PDF) is an accompanying editorial by Denise L. Faustman, M.D., Ph.D. See also Type 1 Diabetes Vaccine May Preserve Some Insulin Production (includes audio clip), New Vaccine May Help Type 1 Diabetics in Future; Early study finds it appears to sustain insulin production in the newly diagnosed and Diamyd® Study Published In Prestigious New England Journal Of Medicine.
  67. High prevalence of vitamin D deficiency in type 1 diabetes mellitus and healthy children.
  68. Curative and beta cell regenerative effects of alpha-1-antitrypsin treatment in autoimmune diabetic NOD mice. See also AAT Protein Restores Blood Glucose in Type 1 Diabetes Model.
  69. Glucagon like peptide-2 reduces intestinal permeability but does not modify the onset of type 1 diabetes in the non obese diabetic mouse. Free full text available in PDF format.
  70. Food consumption and the risk of type 1 diabetes in children and youth: a population-based, case-control study in Prince Edward Island, Canada.
  71. Low-protein diet for diabetic nephropathy: a meta-analysis of randomized controlled trials.
  72. Researchers Finish Work on Needle-free Glucose Tester.

    8 October 2008

  73. Can glycaemic variability, as calculated from blood glucose self-monitoring, predict the development of complications in type 1 diabetes over a decade?
  74. Participant and parent experiences in the oral insulin study of the Diabetes Prevention Trial for Type 1 Diabetes.
  75. The TrialNet Natural History Study of the Development of Type 1 Diabetes: objectives, design, and initial results.
  76. JDRF randomized clinical trial to assess the efficacy of real-time continuous glucose monitoring in the management of type 1 diabetes: research design and methods.
  77. Combination Therapy with Glucagon-Like Peptide-1 and Gastrin Restores Normoglycemia in Diabetic NOD Mice.
  78. Researchers See Neurological Cause of Diabetes in Pancreatic Nociceptors. Also available in PDF format.
  79. Weight gain in early life predicts risk of islet autoimmunity in children with a first degree relative with type 1 diabetes.
  80. Rate of {beta}-cell Destruction in Type 1 Diabetes Influences the Development of Diabetic Retinopathy: Protective Effect of Residual {beta}-cell Function for More Than 10 Years. Free full text available in PDF format.
  81. Effect of candesartan on prevention (DIRECT-Prevent 1) and progression (DIRECT-Protect 1) of retinopathy in type 1 diabetes: randomised, placebo-controlled trials.
  82. Quantitative Assessment of Early Diabetic Retinopathy Using Fractal Analysis.
  83. Predictive value of color Doppler imaging in an evaluation of retrobulbar blood flow perturbation in young type-1 diabetic patients with regard to dyslipidemia.
  84. Role of Humphrey-Matrix Frequency Doubling Technology Perimetry threshold strategy in the Early Diagnosis of Retinopathy in Type 1 Diabetes.
  85. Elevated plasma adiponectin and decreased plasma homocysteine and asymmetric dimethylarginine in children with type 1 diabetes.
  86. Follow up analysis of genome-wide association data identifies novel loci for type 1 diabetes.
  87. Insulin gene mutations as cause of diabetes in children negative for five type 1 diabetes autoantibodies.
  88. Safety and efficacy of inhaled human insulin (Exubera(R)) during discontinuation and readministration of therapy in adults with type 1 diabetes: A 3-year randomized controlled trial.
  89. Assessment of long-term immunological and pulmonary safety of inhaled human insulin with up to 24 months of continuous therapy.
  90. Effects of inhaled human insulin on airway lining fluid composition in adults with diabetes.
  91. NIH Launches New Web Site for Parents on Medical Research Studies for Children. See also the Children & Clinical Studies web site.

    1 October 2008

  92. Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial.
  93. Innate immunity and intestinal microbiota in the development of Type 1 diabetes.
  94. The "Perfect Storm" for Type 1 Diabetes: The Complex Interplay Between Intestinal Microbiota, Gut Permeability, and Mucosal Immunity.
  95. Combination therapy with glucagon-like peptide-1 and gastrin induces beta-cell neogenesis from pancreatic duct cells in human islets transplanted in immunodeficient diabetic mice.
  96. Hs-CRP is associated with weight, BMI, and female sex but not with endothelial function in children with type 1 diabetes.
  97. Glycaemic variability and inflammation in subjects with metabolic syndrome.
  98. Taurine rescues vascular endothelial dysfunction in streptozocin-induced diabetic rats: Correlated with downregulation of LOX-1 and ICAM-1 expression on aortas.
  99. Prolonged Insulin Independence After Islet Allotransplants in Recipients with Type 1 Diabetes.
  100. Prolonged antidiabetic effect of zinc-crystallized insulin loaded glycol chitosan nanoparticles in type 1 diabetic rats.
  101. Prevalence of type 1 diabetes mellitus in Saudi Arabian children and adolescents.

    21 September 2008

  102. Inflammation and Progressive Nephropathy in Type 1 Diabetes Mellitus in the Diabetes Control and Complications Trial (DCCT).
  103. Tissue- and age-specific changes in gene expression during disease induction and progression in NOD mice. See also Type 1 Diabetes May Result From Good Genes Behaving Badly.
  104. High-dose total body irradiation and bone marrow cells may improve efficiency of bone marrow transplantation therapy in treating type 1 diabetes.
  105. Association of Urinary Bisphenol A Concentration With Medical Disorders and Laboratory Abnormalities in Adults. Free full text available in HTML and PDF formats. See also Researchers link BPA exposure to health concerns, Worries in a bottle and Bottle, container chemical tied to diabetes, heart disease.

    20 September 2008

  106. Making insulin-deficient type 1 diabetic rodents thrive without insulin.
  107. Human amnion epithelial cells can be induced to differentiate into functional insulin-producing cells.
  108. Oxidant/antioxidant status and hyperfiltration in young patients with type 1 diabetes mellitus.
  109. In Vivo Protection against Retinal Neurodegeneration by Sigma Receptor 1 Ligand (+)-Pentazocine. See also Receptor activation protects retina from diabetes destruction.
  110. Glucocorticoid Receptor Blockade Normalizes Hippocampal Alterations and Cognitive Impairment in Streptozotocin-Induced Type 1 Diabetes Mice.
  111. Prevalence of allergic symptoms among children with diabetes mellitus type 1 of different socioeconomic status.
  112. Mouse study points researchers toward early trigger for type-1 diabetes.
  113. Effect of HLA Genotype or CTLA-4 Polymorphism on Cytokine Response in Healthy Children.
  114. Methylenetetrahydrofolate reductase and methionine synthase reductase gene polymorphisms and protection from microvascular complications in adolescents with type 1 diabetes.
  115. Therapeutic benefits of regulating inflammation in autoimmunity.
  116. Endogenous secretory RAGE but not soluble RAGE is associated with carotid atherosclerosis in type 1 diabetes patients.
  117. Incidence of diabetes mellitus among children of Italian migrants substantiates the role of genetic factors in the pathogenesis of type 1 diabetes.
  118. Increasing incidence of type 1 diabetes in children aged 0-14 years in Harbin, China (1990-2000).
  119. Autoimmune diabetes in adults: lessons from the UKPDS.

    7 September 2008

  120. Worldwide childhood type 1 diabetes incidence – what can we learn from epidemiology? Free full text available in HTML and PDF formats.
  121. Temporal trends of HLA genotype frequencies of type 1 diabetes patients in Sweden from 1986 to 2005 suggest altered risk.
  122. Vitamin D and living in northern latitudes--an endemic risk area for vitamin D deficiency.
  123. The association between ketoacidosis and 25(OH)-vitamin D levels at presentation in children with type 1 diabetes mellitus.
  124. Age at diagnosis, gender, and metabolic control in children with type 1 diabetes.
  125. HIS modelling and simulation based cost-benefit analysis of a telemedical system for closed-loop diabetes therapy.
  126. Plasminogen activator inhibitor-1 is associated with coronary artery calcium in Type 1 diabetes.
  127. Pancreas transplantation in Shiraz organ transplant center; the first Iranian experience. Free full text available in PDF format.
  128. Human alpha 1-antitrypsin therapy induces fatal anaphylaxis in non-obese diabetic mice.
  129. Association of Brominated Flame Retardants With Diabetes and Metabolic Syndrome in the U.S. Population, 2003–2004.

    7 September 2008

  130. In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. See also Diabetes researchers convert pancreas cells to produce insulin, New technique finds a faster way to change one cell type into another, and Researchers Create Insulin-Producing Cells from Adult Pancreatic Cells.
  131. Selective death of autoreactive T cells in human diabetes by TNF or TNF receptor 2 agonism. See also Potential Diabetes Treatment Selectively Kills Autoimmune Cells From Human Patients.
  132. Increased concentrations of soluble CD40 ligand may help to identify type 1 diabetic adolescents and young adults at risk for developing persistent microalbuminuria.
  133. Serum platelet-activating factor acetylhydrolase activity: A novel potential inflammatory marker in type 1 diabetes.
  134. Correlation of different circulating endothelial progenitor cells to stages of diabetic retinopathy - first in vivo data.

    24 August 2008

  135. STAT4: A risk factor for type 1 diabetes?
  136. Interferon-{alpha} initiates type 1 diabetes in nonobese diabetic mice.
  137. T Regulatory Cells in Autoimmune Diabetes: Past Challenges, Future Prospects.
  138. Immunogenicity of human and bovine insulin in type 1 diabetes mellitus patients.
  139. Pathology of an islet transplant 2 years after transplantation: evidence for a nonimmunological loss.
  140. Plasma osteoprotegerin levels predict cardiovascular and all-cause mortality and deterioration of kidney function in type 1 diabetic patients with nephropathy.

    17 August 2008

  141. Diffusion Tensor Imaging (DTI) identifies deficits in white matter microstructure in subjects with type 1 diabetes mellitus that correlate with reduced neurocognitive function.
  142. Intake of antioxidant vitamins and trace elements during pregnancy and risk of advanced beta cell autoimmunity in the child.
  143. Targeting CD22 reprograms B cells and reverses autoimmune diabetes.
  144. Insulin protein and proliferation in ductal cells in the transplanted pancreas of patients with type 1 diabetes and recurrence of autoimmunity.
  145. Extracellular matrix gel is necessary for in vitro cultivation of insulin producing cells from human umbilical cord blood derived mesenchymal stem cells. Free full text available in HTML and PDF formats.
  146. Analysis of pancreas tissue in a child positive for islet cell antibodies.
  147. Abrupt onset of type 1 diabetes mellitus during recombinant interferon-alpha 2b therapy in a patient with chronic hepatitis B.
  148. Protein and glutamine kinetics during counter-regulatory failure in type 1 diabetes.
  149. Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice. Free full text available in PDF format.

    10 August 2008

  150. Maternal enterovirus infection during pregnancy as a risk factor in offspring diagnosed with type 1 diabetes between 15 and 30 years of age. Free full text available in HTML and PDF formats.
  151. Dietary Glycemic Index, Development of Islet Autoimmunity, and Subsequent Progression to Type 1 Diabetes in Young Children. Free full text available in PDF format.
  152. Gene gun-mediated DNA vaccination enhances antigen-specific immunotherapy at a late preclinical stage of type 1 diabetes in nonobese diabetic mice.
  153. Effects of glucagon on islet beta cell function in patients with diabetes mellitus.
  154. Spectrum of neurological syndromes associated with glutamic acid decarboxylase antibodies: diagnostic clues for this association.
  155. Prevention of type 1 diabetes in NOD mice by genetic engineering of hematopoietic stem cells.
  156. The effect of long-term insulin treatment with and without antecedent hypoglycemia on neuropeptide and corticosteroid receptor expression in the brains of diabetic rats.

    3 August 2008

  157. Oral benfotiamine plus alpha-lipoic acid normalises complication-causing pathways in type 1 diabetes.
  158. Correction of a diabetes mellitus type 1 on primate with encapsulated islet of pig pancreatic transplant.
  159. IGF-1 and IGF-Binding Proteins and Bone Mass, Geometry and Strength: Relation to Metabolic Control in Adolescent Girls with Type 1 Diabetes.
  160. IGF-I mediates regeneration of endocrine pancreas by increasing beta cell replication through cell cycle protein modulation in mice.
  161. Monitoring of early and advanced glycation in relation to the occurrence of microvascular complications in children and adolescents with type 1 diabetes mellitus.
  162. Randomized, controlled, parallel-group prospective study to investigate the clinical effectiveness of early insulin treatment in patients with latent autoimmune diabetes in adults. Free full text available in PDF format.

    27 July 2008

  163. Glucose and C-peptide Changes in the Peri-Onset Period of Type 1 Diabetes in the Diabetes Prevention Trial-Type 1.
  164. Lower levels of circulating IGF-I in Type 1 diabetic women with frequent severe hypoglycaemia during pregnancy.
  165. Cognitive impairment correlates to low auditory event-related potential amplitudes in type 1 diabetes.
  166. Polyclonal adaptive regulatory CD4 cells that can reverse type I diabetes become oligoclonal long-term protective memory cells.
  167. One amino acid difference is critical for suppression of the development of experimental autoimmune diabetes (EAD) with intravenous injection of insulinB:9-23 peptide.
  168. A human type 1 diabetes susceptibility locus maps to chromosome 21q22.3.

    20 July 2008

  169. Therapies aimed at preservation or restoration of beta cell function in type 1 diabetes.
  170. Vitamin D signaling in immune-mediated disorders: Evolving insights and therapeutic opportunities.
  171. Increased retinopathy occurrence in type 1 diabetes patients with increased serum levels of the advanced glycation endproduct hydroimidazolone.
  172. Brain GLP-1 regulates arterial blood flow, heart rate and insulin sensitivity.
  173. The Use of Exenatide in Islet Transplant Recipients with Chronic Allograft Dysfunction: Safety, Efficacy, and Metabolic Effects.
  174. Current challenges in islet transplantation.
  175. Simultaneous Islet-Kidney Transplantation in 7 Patients of Type 1 Diabetes with End-stage Renal Disease using a glucocorticoid-free immunosuppressive regimen with alemtuzumab induction.
  176. Reversal of new-onset type 1 diabetes in mice by syngeneic bone marrow transplantation.
  177. Cerebral Blood Flow and Cerebral Edema in Rats with Diabetic Ketoacidosis.
  178. Effect of Aging on A1C Levels in Persons without Diabetes: Evidence from the Framingham Offspring Study and NHANES 2001-2004.
  179. The Mixed Meal Tolerance Test Versus The Glucagon Stimulation Test For The Assessment Of Beta-Cell Function In Therapeutic Trials In Type 1 Diabetes.
  180. Conserved T cell receptor {alpha}-chain induces insulin autoantibodies. Free full text available in PDF format.
  181. Reduced Frequency of Peripheral Plasmacytoid Dendritic Cells in Type 1 Diabetes.
  182. Gene therapy for type 1 diabetes mellitus in rats by gastrointestinal administration of chitosan nanoparticles containing human insulin gene.
  183. Insulin gene polymorphisms in type 1 diabetes, Addison's disease and the polyglandular autoimmune syndrome type II. Free full text available in HTML and PDF formats.

    13 July 2008

  184. Acute hyperglycaemia induces an inflammatory response in young patients with type 1 diabetes.
  185. The effects of diabetes and aminoguanidine treatment on endothelial function in a primate model of type 1 diabetes.
  186. The putative protective role of hepatitis B virus (HBV) infection against autoimmune disorders.
  187. Clinical manifestations and beta cell function in Swedish diabetic children have remained unchanged during the last 25 years.
  188. Random C peptide measurement in adults with clinical diagnosis of type 1 diabetes. Free Portuguese language full text available in HTML format. (PDF not working at the time of this newsletter.)
  189. Advances in type I diabetes associated tolerance mechanisms.
  190. Boosting Survival Of Insulin-cell Transplants For Type 1 Diabetes.

    6 July 2008

  191. C-Peptide effects on renal physiology and diabetes. Free full text available in HTML and PDF formats.
  192. Control of autoimmune diseases by the vitamin D endocrine system.
  193. Innate immunity and its role in type 1 diabetes.
  194. The accelerator hypothesis and increasing incidence of type 1 diabetes.
  195. Too Much Glucagon, Too Little Insulin; Time course of pancreatic islet dysfunction in new-onset type 1 diabetes.
  196. Association of Intrauterine Exposure to Maternal Diabetes and Obesity With Type 2 Diabetes in Youth; The SEARCH Case-Control Study.
  197. Postnatal expansion of the pancreatic beta-cell mass is dependent on survivin.

    29 June 2008

  198. Differentiation of mouse nuclear transfer embryonic stem cells into functional pancreatic beta cells.
  199. Participation in pediatric epidemiologic research: The SEARCH for Diabetes in Youth Study experience.
  200. Characterization of the humoral immune response to islet antigen 2 in children with newly diagnosed type 1 diabetes.
  201. Reference value of transcutaneous oxygen measurement in diabetic patients compared with nondiabetic patients.
  202. Dirty electricity elevates blood sugar among electrically sensitive diabetics and may explain brittle diabetes.
  203. Reduced short-term complexity of heart rate and blood pressure dynamics in patients with diabetes mellitus type 1: multiscale entropy analysis.
  204. Primary prevention of diabetes mellitus type 2 and cardiovascular diseases using a cognitive behavior program aimed at lifestyle changes in people at risk: design of a randomized controlled trial. Free full text available in PDF format.

    22 June 2008

  205. Cellular islet autoimmunity associates with clinical outcome of islet cell transplantation. Free full text available in HTML and PDF formats.
  206. Variation in Associations between Allelic Variants of the Vitamin D Receptor Gene and Onset of Type 1 Diabetes Mellitus by Ambient Winter Ultraviolet Radiation Levels: A Meta-Regression Analysis.
  207. T-cell reactivity to insulin peptide A1-12 in children with recently diagnosed type 1 diabetes or multiple beta-cell autoantibodies.
  208. Psychological stress as a factor potentially contributing to the pathogenesis of Type 1 diabetes mellitus.
  209. Human adipose tissue-derived mesenchymal stem cells combined with hematopoietic stem cell transplantation synthesize insulin.
  210. The novel inosine analogue, INO-2002, protects against diabetes development in multiple-low-dose-streptozotocin and NOD mouse models of Type I .
  211. Heparanase prevents the development of type 1 diabetes in non-obese diabetic mice by regulating T-cell activation and cytokines production.
  212. The K(ATP) Channel and Neonatal Diabetes. Free full text available in PDF format.

    15 June 2008

  213. The association between ultraviolet B irradiance, vitamin D status and incidence rates of type 1 diabetes in 51 regions worldwide.
  214. Continuous rise in incidence of childhood Type 1 diabetes in Germany.
  215. Does social-economical transformation influence the incidence of type 1 diabetes mellitus? A Polish example.
  216. Type 1 diabetes: increased height and weight gains in early childhood.
  217. Atopy, home environment and the risk of childhood-onset type 1 diabetes: a population-based case-control study.
  218. Young children (<5 yr) and adolescents (>12 yr) with type 1 diabetes mellitus have low rate of partial remission: diabetic ketoacidosis is an important risk factor.
  219. Adiponectin and catecholamine concentrations during acute exercise in children with type 1 diabetes.
  220. Basal insulin and total daily insulin dose in children with type 1 diabetes using insulin pumps.
  221. Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the DPT1 trial.
  222. Cardiac repolarization during hypoglycaemia in type 1 diabetes: impact of basal renin-angiotensin system activity.
  223. Prevalence of Structural Central Nervous System Abnormalities in Early-Onset Type 1 Diabetes Mellitus.
  224. Metabolic Phenotypes, Vascular Complications and Premature Deaths in a Population of 4,197 Patients with Type 1 Diabetes.
  225. Toward a cure for type 1 diabetes mellitus: diabetes-suppressive dendritic cells and beyond.
  226. Diabetes: 1 and 2, or one and the same? Progress with the accelerator hypothesis.

    8 June 2008

  227. Presence of diabetic ketoacidosis at diagnosis of diabetes mellitus in youth: the Search for Diabetes in Youth Study.
  228. Glycemic instability in type 1 diabetic patients: Possible role of ketosis or ketoacidosis at onset of diabetes.
  229. Insulin Intervention in Slowly Progressive Insulin-Dependent (Type 1) Diabetes Mellitus.
  230. Diabetes mellitus among young adults in Sri Lanka-role of GAD antibodies in classification and treatment: The Sri Lanka Young Diabetes study.
  231. Islet transplantation at the Diabetes Research Institute Japan.
  232. Retinal Arteriolar Dilation Predicts Retinopathy in Adolescents with Type 1 Diabetes.
  233. Evaluation of microvascular endothelial function in patients with type 1 diabetes using laser-Doppler perfusion monitoring: Which method to choose?
  234. Prevalence of type 2 diabetes mellitus among Kuwaiti children and adolescents.
  235. Genetic Determinants and Epidemiology of Cystic Fibrosis-Related Diabetes - Results from a British Cohort of Children and Adults.
  236. Patient-important outcomes in registered diabetes trials.

    1 June 2008

  237. Enhanced levels of cow's milk antibodies in infancy in children who develop type 1 diabetes later in childhood.
  238. Exposure to Environmental Factors in Drinking Water: Risk of Islet Autoimmunity and Type 1 Diabetes - The BABYDIAB Study.
  239. Viral infections in the pathogenesis of autoimmune diseases: focus on type 1 diabetes.
  240. Diabetes: 1 and 2, or one and the same? Progress with the accelerator hypothesis.
  241. Does the secular increase in body mass in children contribute to the increasing incidence of type 1 diabetes?
  242. Type 1 diabetes: increased height and weight gains in early childhood.
  243. Very high and increasing incidence of type 1 diabetes mellitus in Newfoundland and Labrador, Canada.
  244. The effect of oral alpha-lipoic acid on oxidative stress in adolescents with type 1 diabetes mellitus.
  245. Eligen insulin - a system for the oral delivery of insulin for diabetes.
  246. Type 1 diabetes, hyperglycaemia, and the heart.
  247. Recurrences in heart rate dynamics are changed in patients with diabetes mellitus.

    25 May 2008

  248. You can review Abstracts from the 68th Scientific Sessions of the American Diabetes Association.
  249. Vitamin D supplementation in early childhood and risk of type 1 diabetes: a systematic review and meta-analysis. Free full text available in HTML and PDF formats.
  250. Type 1 Diabetes In Finnish Children Skyrockets. See also Time trends in the incidence of type 1 diabetes in Finnish children: a cohort study (free registration required).
  251. The Diabetes Research in Children Network: Availability of Protocol Datasets. Free full text available in HTML and PDF formats. See also the Diabetes Research in Children Network web site for the datasets.
  252. Systemic administration of multipotent mesenchymal stromal cells reverts hyperglycemia and prevents nephropathy in type 1 diabetic mice.
  253. Metabolic Control Improves Long-Term Renal Allograft and Patient Survival in Type 1 Diabetes.
  254. Insulin sensitivity in type 2 diabetes is closely associated with LDL particle size. Free full text available in PDF format.

    18 May 2008

  255. C-Peptide and its C-terminal fragments improve erythrocyte deformability in type 1 diabetes patients.
  256. Oxidative stress: the vulnerable beta-cell.
  257. Dietary Toxins, Endoplasmic Reticulum (ER) Stress and Diabetes.
  258. Optical coherence tomography-based continuous noninvasive glucose monitoring in patients with diabetes.
  259. How would patients behave if they were continually informed of their blood glucose levels? A simulation study using a "virtual" patient.
  260. The rising incidence of type 1 diabetes is accounted for by cases with lower risk HLA genotypes.
  261. Role of advanced glycation end products (AGEs) and oxidative stress in diabetic retinopathy.
  262. Early signs of left ventricular dysfunction in adolescents with Type 1 diabetes mellitus: The importance of impaired circadian modulation of blood pressure and heart rate.

    11 May 2008

  263. Dendritic cells in islets of Langerhans constitutively present ß cell-derived peptides bound to their class II MHC molecules. Free full text available in HTML and PDF formats. See also Suspected cause of type 1 diabetes caught "red-handed" for the first time.
  264. Maternal type 1 diabetes reduces the risk of islet autoantibodies: relationships with birthweight and maternal HbA(1c).
  265. Metabolic Profile and Nitric Oxide Synthase Expression of Skeletal Muscle Fibers are Altered in Patients with Type 1 Diabetes.
  266. Relation of Time of Introduction of Cow Milk Protein to an Infant and Risk of Type-1 Diabetes Mellitus. Free full text available in HTML and PDF formats. See also Link between early consumption of cows' milk and Type-1 diabetes.

    4 May 2008

  267. Fully Automated Closed-Loop Insulin Delivery Versus Semiautomated Hybrid Control in Pediatric Patients With Type 1 Diabetes Using an Artificial Pancreas.
  268. Prevention of type 1 diabetes: the time has come.
  269. Modulating the natural history of type 1 diabetes in children at high genetic risk by mucosal insulin immunization.
  270. Vitamin D and the Diabetic Patient. Free registration required.
  271. Genetic and humoral autoimmunity markers of type 1 diabetes: from theory to practice. Free Portuguese language full text available in HTML and PDF formats.
  272. Has Time Come for New Goals in Human Islet Transplantation?
  273. Combined Islet and Hematopoietic Stem Cell Allotransplantation: A Clinical Pilot Trial to Induce Chimerism and Graft Tolerance.
  274. Islet Transplantation for Brittle Type 1 Diabetes: The UIC Protocol.
  275. Glycated Albumin is a Better Indicator for Glucose Excursion than Glycated Hemoglobin in Type 1 and Type 2 Diabetes. Free full text available in PDF format.
  276. Differences in Metabolites in Pain-Processing Brain Regions in Patients With Diabetes and Painful Neuropathy.
  277. Heritability of proliferative diabetic retinopathy.
  278. Intracellular signalling by C-peptide. Free full text available in HTML and PDF formats.
  279. Potencial role of stem cell therapy in type 1 diabetes mellitus. Free full text available in HTML and PDF formats.

    27 April 2008

  280. Infiltration of forkhead box P3-expressing cells in small intestinal mucosa in coeliac disease but not in type 1 diabetes.
  281. Relation of circulating concentrations of chemokine receptor CCR5 ligands to C-peptide, proinsulin and HbA1c and disease progression in type 1 diabetes.
  282. Fulminant type 1 diabetes as a model of nature to explore the role of C-peptide.
  283. The mechanisms that underlie glucose sensing during hypoglycaemia in diabetes.
  284. Association analysis of the type 2 diabetes loci in type 1 diabetes.
  285. Prevalence of atopy in children with type 1 diabetes mellitus, hepatitis B virus carriers, and healthy children: Role of T helper 1 (Th1)-type immune response.
  286. Immunological efficacy of heat shock protein 60 peptide DiaPep277(TM) therapy in clinical type I diabetes.
  287. Islet transplantation in patients with autoimmune diabetes induces homeostatic cytokines that expand autoreactive memory T cells. Free full text available in HTML and PDF formats.
  288. Immunosuppression in islet transplantation. Free full text available in HTML and PDF formats.
  289. Elevated Catalase And Heme Oxygenase-1 May Contribute To Improved Postischaemic Cardiac Function In Long-term Type 1 Diabetes.

    20 April 2008

  290. Angiotensinogen gene T235 variant: a marker for the development of persistent microalbuminuria in children and adolescents with type 1 diabetes mellitus.
  291. Angiotensin-converting enzyme activity and cognitive impairment during hypoglycaemia in healthy humans.
  292. The influence of autonomic neuropathy on cough reflex sensitivity in children with diabetes mellitus type 1. Free full text available in PDF format.
  293. Diabetes-Enhanced Tumor Necrosis Factor-{alpha} Production Promotes Apoptosis and the Loss of Retinal Microvascular Cells in Type 1 and Type 2 Models of Diabetic Retinopathy.
  294. Cross-sectional associations of C-reactive protein with vascular risk factors and vascular complications in the DCCT/EDIC cohort.
  295. Postural blood pressure changes and associated factors in long-term Type 1 diabetes: Wisconsin Epidemiologic Study of Diabetic Retinopathy.
  296. Rotavirus Infection Accelerates Type 1 Diabetes in Mice with Established Insulitis.
  297. Control of pancreatic beta-cell fate by insulin signaling: The sweet spot hypothesis.
  298. Relation of Time of Introduction of Cow Milk Protein to an Infant and Risk of Type-1 Diabetes Mellitus.

    13 April 2008

  299. The Renal Hemodynamic Effect of Cyclooxygenase 2 Inhibition in Young Men and Women with Uncomplicated Type 1 Diabetes Mellitus.
  300. Association between retinopathy, microalbuminuria and coronary perfusion in young patients with type 1 diabetes mellitus.
  301. Effect Of Oral Amino Acid On Counterregulatory Responses And Cognitive Function During Insulin-induced Hypoglycemia In Non-diabetic And Type 1 Diabetic People.

    6 April 2008

  302. Altered Kinetics of Interleukin-6 and Other Inflammatory Mediators During Exercise in Children With Type 1 Diabetes.
  303. Type 1 diabetes: can exercise impair the autoimmune event? The L-arginine/glutamine coupling hypothesis.
  304. The Role of Advanced Glycation End Products in Progression and Complications of Diabetes.
  305. Post-Meal Glucose Peaks at Home Associate with Carotid Intima-Media Thickness in Type 2 Diabetes.
  306. Continuous, but Not Occasional, Oral Ethanol Intake Reduces the Success of Intraportal Transplanted Islets of Langerhans: An Experimental Study.
  307. Biodritin microencapsulated human islets of langerhans and their potential for type 1 diabetes mellitus therapy.
  308. Treatment of Diabetic Rats with Encapsulated Islets.
  309. Ingested (oral) SIRS peptide 1-21 suppresses type 1 diabetes in NOD mice.
  310. PAX4 Enhances Beta-Cell Differentiation of Human Embryonic Stem Cells. See also Stem cell breakthrough offers diabetes hope.

    30 March 2008

  311. Autologous umbilical cord blood infusion for type 1 diabetes.
  312. Lack of association of vitamin D receptor gene polymorphisms with susceptibility to type 1 diabetes mellitus in the Portuguese population.
  313. Incidence of children with slowly progressive form of type 1 diabetes detected by the urine glucose screening at schools in the Tokyo Metropolitan Area.
  314. The lack of anti-idiotypic antibodies, not the presence of the corresponding autoantibodies to glutamate decarboxylase, defines type 1 diabetes.
  315. The relationship between risk factors and mortality in type 1 diabetic patients in Europe, the EURODIAB Prospective Complications Study (PCS).
  316. Having One Kidney Does Not Accelerate the Rate of Development of Diabetic Nephropathy Lesions in Type 1 Diabetic Patients.
  317. Oxidative stress parameters as possible urine markers in patients with diabetic nephropathy.
  318. Improved Metabolic Control and Quality of Life in Seven Patients With Type 1 Diabetes Following Islet After Kidney Transplantation.
  319. HLA sensitization in islet transplantation.
  320. Long-term engraftment following transplantation of pig pancreatic primordia into non-immunosuppressed diabetic rhesus macaques.

    23 March 2008

  321. Effect of C-peptide on diabetic neuropathy in patients with type 1 diabetes.
  322. Efficacy, safety and tolerability of pregabalin treatment of painful diabetic peripheral neuropathy: findings from 7 randomized, controlled trials across a range of doses.
  323. Risk of microalbuminuria and progression to macroalbuminuria in a cohort with childhood onset type 1 diabetes: prospective observational study.
  324. Serum adiponectin and progression of diabetic nephropathy in patients with type 1 diabetes.
  325. Sex Hormone Binding Globulin and Testosterone in Individuals with Childhood Diabetes.
  326. Trends in High-Risk HLA Susceptibility Genes Among Colorado Youth with Type 1 Diabetes.
  327. Improved Metabolic Control and Quality of Life in Seven Patients With Type 1 Diabetes Following Islet After Kidney Transplantation.

    16 March 2008

  328. Vitamin D Supplementation in Early Childhood and Risk of Type 1 Diabetes: a Systematic Review and Meta-analysis. See also Vitamin D Lowers Diabetes Risk and Extra Vitamin D In Early Childhood Cuts Adult Diabetes Risk.
  329. Progression to type 1 diabetes and autoantibody positivity in relation to HLA-risk genotypes in children participating in the ABIS study.
  330. Markers of endothelial dysfunction and inflammation in type 1 diabetic patients with or without diabetic nephropathy followed for 10 years: association with mortality and decline of glomerular filtration rate.
  331. Genetic variation and activity of the renin-angiotensin system and severe hypoglycemia in type 1 diabetes.
  332. The Arg16Gly variant of the beta2-adrenergic receptor predisposes to hypoglycemia unawareness in type 1 diabetes mellitus.
  333. A comparison of the levels of hepatocyte growth factor in serum in patients with type 1 diabetes mellitus with different stages of diabetic retinopathy.
  334. Hormonal profile of diabetic men and the potential link to prostate cancer.
  335. A Comparison of Protocols used to Generate Insulin-producing Cell Clusters from Mouse Embryonic Stem Cells.
  336. Over 500 solitary pancreas transplants in nonuremic patients with brittle diabetes mellitus.

    9 March 2008

  337. A Microsphere-based Vaccine Prevents And Reverses New-onset Autoimmune Diabetes.
  338. Noninvasive in vivo imaging of pancreatic islet cell biology. Free full text available through the DRI in PDF format. See also Diabetes Research Institute Develops Revolutionary Technique To Accelerate Research; First Ever "Living Window" Lets Scientists View Cell Activity, Processes in Real Time.
  339. In Vitro Proliferation Of Cells Derived From Adult Human Beta Cells Revealed By Cell-lineage Tracing.
  340. Serum alpha- and gamma-tocopherol concentrations and risk of advanced beta cell autoimmunity in children with HLA-conferred susceptibility to type 1 diabetes mellitus.
  341. Serial Measurements of Cystatin C are More Accurate than Creatinine-based Methods in Detecting Declining Renal Function in Type 1 Diabetes.
  342. Glucose variability, blood pressure and arterial stiffness in type 1 diabetes.
  343. Short-term heart rate complexity is reduced in patients with type 1 diabetes mellitus.
  344. Cutaneous Microvascular Dysfunction is associated with HLA-DQ in Youths with Type 1 Diabetes.
  345. Abnormal NF-kappa-B Function Characterizes Human Type 1 Diabetes Dendritic Cells and Monocytes. See also Simple test to unlock the diabetes roulette in children.
  346. Genetic Similarities Between LADA, Type 1 And Type 2 Diabetes.

    2 March 2008

  347. First-Trimester Human Fetal Pancreas Transplantation for Type 1 Diabetes Treatment.
  348. A Risk Score for Type 1 Diabetes Derived From Autoantibody-Positive Participants in the Diabetes Prevention Trial–Type 1.
  349. Association of IL-1ra and adiponectin with C-peptide and remission in patients with type 1 diabetes.
  350. Endothelial dysfunction and microvascular complications in type 1 diabetes mellitus.
  351. Oscillating glucose is more deleterious on endothelial function and oxidative stress than mean glucose in normals and type 2 diabetic patients.
  352. Atrial natriuretic peptide prevents diabetes-induced endothelial dysfunction.
  353. Bloodless Diabetes Monitoring; A new noninvasive tool uses electromagnetic waves to measure glucose levels.
  354. A New Zealand linkage study examining the associations between glycosylated haemoglobin concentration and mortality.
  355. Differential sensitivity of men and women to anorexigenic and memory improving effects of intranasal insulin. See also Insulin administered intranasally may lower food intake in men, improve memory in women.

    24 February 2008

  356. Caesarean section is associated with an increased risk of childhood-onset type 1 diabetes mellitus: a meta-analysis of observational studies.
  357. Cytomegalovirus infection in early infancy: risk of induction and progression of autoimmunity associated with type 1 diabetes.
  358. Winner of the 2007 Society for Thermal Medicine Young Investigator Award Fever-range whole body hyperthermia prevents the onset of type 1 diabetes in non-obese diabetic mice.
  359. Generation of Insulin-producing Beta Cells from Stem Cells - Perspectives for Cell Therapy in Type 1 Diabetes.

    17 February 2008

  360. Cord blood islet autoantibodies and seasonal association with the type 1 diabetes high-risk genotype.
  361. Environmental risk factors in prediction of childhood prediabetes. Free full text available in PDF format.
  362. The islet autoantibody titres: their clinical relevance in latent autoimmune diabetes in adults (LADA) and the classification of diabetes mellitus.
  363. Glycemic Variability: Should we and can we prevent it?
  364. Phenotype changes at the onset of type 1 diabetes in young adults from a Mediterranean area throughout the last decade.
  365. High-Normal Serum Uric Acid Is Associated with Impaired Glomerular Filtration Rate in Nonproteinuric Patients with Type 1 Diabetes.
  366. Glycosaminoglycans urinary excretion as a marker of the early stages of diabetic nephropathy and the disease progression.
  367. ADVANCE Does Not Confirm ACCORD Results. See also Aggressive diabetes treatment affirmed in new study.

    10 February 2008

  368. Fully Automated Closed-Loop Insulin Delivery vs. Semi-Automated Hybrid Control in Pediatric Patients with Type 1 Diabetes using an Artificial Pancreas.
  369. A unifying hypothesis on the development of type 1 diabetes and celiac disease: Gluten consumption may be a shared causative factor.
  370. Association of Urinary Inflammatory Markers and Renal Decline in Microalbuminuric Type 1 Diabetics.
  371. The effect of oral folic acid upon plasma homocysteine, endothelial function and oxidative stress in patients with type 1 diabetes and microalbuminuria.
  372. Diagnostic potential of oxidative stress markers in children and adolescents with type 1 diabetes.
  373. HLA DR-DQ Haplotypes and Genotypes and Type 1 Diabetes Risk: Analysis of the Type 1 Diabetes Genetics Consortium Families.
  374. A study of diabetes mellitus within a large sample of Australian twins.
  375. Diabetes Study Partially Halted After Deaths (type 2 diabetes). For more information, see For Safety, NHLBI Changes Intensive Blood Sugar Treatment Strategy in Clinical Trial of Diabetes and Cardiovascular Disease, the ADA Position on the ACCORD study, and the ACCORD study web site. Compare also to Effect of a Multifactorial Intervention on Mortality in Type 2 Diabetes.

    3 February 2008

  376. Is C-peptide replacement the missing link for successful treatment of neurological complications in type 1 diabetes?
  377. Does the secular increase in body mass in children contribute to the increasing incidence of type 1 diabetes?
  378. Time series analysis of ultraviolet B radiation and type 1 diabetes in Newfoundland.
  379. Very high and increasing incidence of type 1 diabetes mellitus in Newfoundland and Labrador, Canada.
  380. Maternal diet during pregnancy and islet autoimmunity in offspring.
  381. The Effect of Glycemic Exposure on the Risk of Microvascular Complications in the Diabetes Control and Complications Trial -- Revisited.
  382. Genetically engineered K cells provide sufficient insulin to correct hyperglycemia in a nude murine model.
  383. C-reactive Protein In Relation To The Development Of Microalbuminuria In Type 1 Diabetes: The Oxford Regional Prospective Study.
  384. Salsalate Improves Glycemia and Inflammatory Parameters in Obese Young Adults. See also Mild NSAID Hints at Type 2 Diabetes Prevention.

    27 January 2008

  385. Peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism, cod liver oil and risk of type 1 diabetes.
  386. Identification of a Molecular Signature in Human Type 1 Diabetes Mellitus Using Serum and Functional Genomics.
  387. The effects of metabolic control on oxidized low-density lipoprotein antibodies in children and adolescents with type 1 diabetes mellitus.
  388. Sustained IL-1alpha, IL-4, and IL-6 elevations following correction of hyperglycemia in children with type 1 diabetes mellitus.
  389. Plasma {alpha}-defensin is associated with cardiovascular morbidity and mortality in type 1 diabetic patients. Free full text available in PDF format.
  390. Interleukin-12 and tumour necrosis factor-alpha equilibrium is a prerequisite for clinical course free from late complications in children with type 1 diabetes mellitus.
  391. Gender differences and temporal variation in the incidence of type 1 diabetes: results of 8012 cases in the nationwide Diabetes Incidence Study in Sweden 1983-2002.
  392. Transmission of type 1 diabetes by bone marrow transplantation: A case report.
  393. Hemoglobin and overt nephropathy complications in type 1 diabetes.
  394. Dietary Intake and the Development of the Metabolic Syndrome. The Atherosclerosis Risk in Communities Study. See also Burgers, Fries, and Diet Soda Are Recipe for Metabolic Syndrome.

    13 January 2008

  395. Vaccination against self to prevent autoimmune disease: the type 1 diabetes model.
  396. Mutations in the Insulin Gene can Cause MODY and Autoantibody-Negative Type 1 Diabetes.
  397. The Relationship Between Diabetes Mellitus and Traffic-Related Air Pollution.
  398. AIR® Inhaled Insulin versus Subcutaneous Insulin: Pharmacokinetics, Glucodynamics, and Pulmonary Function in Asthma.
  399. Relationship between plasma sialic acid and fibrinogen concentration and incident micro- and macrovascular complications in type 1 diabetes. The EURODIAB Prospective Complications Study (PCS).
  400. Hypothesis-Ultraviolet-B Irradiance and Vitamin D Reduce the Risk of Viral Infections and thus Their Sequelae, Including Autoimmune Diseases and some Cancers.

    6 January 2008

  401. Extent of Beta cell destruction is important but insufficient to predict the onset of type 1 diabetes mellitus. Free full text available in HTML and PDF formats (see link in full text HTML).
  402. Heterozygous Missense Mutations in the Insulin Gene are linked to Permanent Diabetes appearing in the Neonatal Period or in Early-Infancy: A report from the French ND Study Group.
  403. Quantitative Linkage Analysis for Pancreatic B-cell Function and Insulin Resistance in a Large Twin Cohort.
  404. Nanoparticle strategies for the oral delivery of insulin.

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