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Research News From 2009

    30 December 2009

  1. Use of the Site of Subcutaneous Insulin Administration for the Measurement of Glucose in Patients with Type 1 Diabetes.
  2. No evidence of porcine endogenous retrovirus in patients with type 1 diabetes after long-term porcine islet xenotransplantation.
  3. Trends of Earlier and Later Responses of C-peptide to Oral Glucose Challenges with Progression to Type 1 Diabetes in Diabetes Prevention Trial-Type 1 Participants Running Title: C-peptide with Progression to Type 1 Diabetes.
  4. Immunomodulation with heat shock protein DiaPep277 to preserve beta cell function in type 1 diabetes - an update.
  5. Prevalence of Type 1 Diabetes auto-antibodies (GADA, IA2, IAA) in overweight and obese children.
  6. 23 December 2009

  7. Researchers Re-Defining the Concept of a Cure for Diabetes.
  8. Six months of diazoxide treatment at bedtime in newly diagnosed subjects with type 1 diabetes does not influence parameters of beta-cell function and autoimmunity, but improves glycemic control.
  9. Ethnic Differences in Incidence of Type 1 Diabetes among Second-Generation Immigrants and Adoptees from Abroad.
  10. Progression to diabetes in relatives of type 1 diabetic patients: mechanisms and mode of onset.
  11. Gut barrier disruption by an enteric bacterial pathogen accelerates insulitis in NOD mice.
  12. Association between serum levels of the soluble receptor (sRAGE) for advanced glycation endproducts (AGEs) and their receptor (RAGE) in peripheral blood mononuclear cells of children with type 1 diabetes mellitus.
  13. Can Roux-en-Y gastric bypass provide a lifelong solution for diabetes mellitus? Free full text available in PDF format.
  14. 16 December 2009

  15. Population density determines the direction of the association between ambient ultraviolet radiation and type 1 diabetes incidence.
  16. The Geoepidemiology of Type 1 Diabetes.
  17. Tea, Coffee Seem to Protect Against [Type 2] Diabetes.
  18. Age at the Introduction of Solid Foods During the First Year and Allergic Sensitization at Age 5 Years.

    9 December 2009

  19. Researchers stop diabetes progression in a clinical trial discusses Rituximab, B-lymphocyte depletion, and preservation of beta-cell function, previously presented.
  20. Real-time detection of nocturnal hypoglycemic episodes using a novel non-invasive hypoglycemia monitor.
  21. Familial type 1 diabetes mellitus-gender distribution and age at onset of diabetes distinguish between parent-offspring and sib-pair subgroups.
  22. Bone mass and sex steroids in postmenarcheal adolescents and adult women with Type 1 diabetes mellitus.

    2 December 2009

  23. Prevention of type 1 diabetes.
  24. Rituximab, B-lymphocyte depletion, and preservation of beta-cell function. See also Rituximab Protects Insulin Producing Cells in Diabetes.
  25. Autoantigen-specific regulatory T cells induced in patients with type 1 diabetes mellitus by insulin B-chain immunotherapy.

    25 November 2009

  26. Are Hemoglobin Levels Elevated in Type 1 Diabetes?
  27. Treatment of Type 1 Diabetic Patients with Glucagon-Like Peptide-1 (GLP-1) and GLP-1R Agonists.
  28. Improved Insulin Sensitivity After Exercise: Focus on Insulin Signaling.
  29. Progressive Decrease in N-Acetylaspartate/Creatine Ratio in a Teenager with Type 1 Diabetes and Repeated Episodes of Ketoacidosis without Clinically Apparent Cerebral Edema: Evidence for Permanent Brain Injury.

    18 November 2009

  30. A Maternal But Not Paternal Association Of Ambulatory Blood Pressure With Albumin Excretion In Young Offspring With Type 1 Diabetes.
  31. Inflammation markers and metabolic characteristics of subjects with one-hour plasma glucose levels.
  32. Insulin Resistance in Adolescents with Type 1 Diabetes and Its Relationship to Cardiovascular Function.
  33. Changes in Cerebral Blood Flow Detected by SPECT in Type 1 and Type 2 Diabetic Patients.
  34. The assessment of pulmonary diffusing capacity in diabetes mellitus with regard to microalbuminuria.
  35. Low levels of vitamin D in North Indian children with newly diagnosed type 1 diabetes.
  36. Epidemiological perspectives on type 1 diabetes in childhood and adolescence in Germany: 20 years of the DIARY registry.
  37. Early Infant Diet in Children at High Risk for Type 1 Diabetes.
  38. Childhood growth and age at diagnosis with Type 1 diabetes in Colorado young people.
  39. Increasing incidence of childhood type 1 diabetes in Montenegro from 1997 to 2006.
  40. Testing for monogenic diabetes among children and adolescents with antibody-negative clinically defined Type 1 diabetes.

    11 November 2009

  41. Epidemiological perspectives on type 1 diabetes in childhood and adolescence in Germany: 20 years of the DIARY registry.
  42. Microvascular reactivity in type 1 diabetics.
  43. Regulation of oxidative stress by glycaemic control: evidence for an independent inhibitory effect of insulin therapy.

    4 November 2009

  44. Autologous umbilical cord blood transfusion in very young children with type 1 diabetes.
  45. Maternal age at birth and childhood type 1 diabetes: a pooled analysis of 30 observational studies.
  46. The Effect of Direct Renin Inhibition on Renal Hemodynamic Function, Arterial Stiffness and Endothelial Function in Humans with Uncomplicated Type 1 Diabetes Mellitus: A Pilot Study.
  47. A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both HbA1c and glucose.
  48. The influence of physical activity on ghrelin and IGF-1/IGFBP-3 levels in children and adolescents with type 1 diabetes mellitus.

    28 October 2009

  49. Preventing hypoglycemia using predictive alarm algorithms and insulin pump suspension.
  50. Closed-Loop Insulin Delivery Using a Subcutaneous Glucose Sensor and Intra-Peritoneal Insulin Delivery: A Feasibility Study Testing a New Model for the Artificial Pancreas.
  51. Aortic Intima Media Thickness is an Early Marker of Atherosclerosis in Children with Type 1 Diabetes Mellitus.
  52. Nephropathy in Type 1 diabetes is associated with increased circulating activated platelets and platelet hyperreactivity.
  53. Daily vegetable intake during pregnancy negatively associated to islet autoimmunity in the offspring–The ABIS study.
  54. Associations of Serum Concentrations of 25-Hydroxyvitamin D and Parathyroid Hormone with Surrogate Markers of Insulin Resistance among U.S. Adults without Physician-Diagnosed Diabetes: National Health and Nutrition Examination Survey, 2003-2006.
  55. 21 October 2009

  56. Hippocampal Volumes in Youth with Type 1 Diabetes.
  57. Subclinical vascular alterations in young adults with type 1 diabetes detected by arterial tonometry.
  58. Age at Onset Of Type 1 Diabetes in Parents and Recurrence Risk in Offspring.
  59. Factors for thyroid autoimmunity in children and adolescents with type 1 diabetes mellitus.
  60. Latent Autoimmune Diabetes in Adults.
  61. Pancreatic islet transplantation. Free full text available in HTML and PDF formats.
  62. Stem cell therapy for type 1 diabetes mellitus: a review of recent clinical trials. Free full text available in PDF format.
  63. Absence of diabetic retinopathy in a patient who has had diabetes mellitus for 69 years, and inadequate glycemic control: case report. Free full text available in HTML and PDF formats.
  64. 14 October 2009

  65. The incidence of type 1 diabetes is increasing in both children and young adults in Northern Italy: 1984-2004 temporal trends.
  66. Angiotensin-converting enzyme and angiotensin II receptor subtype 2 genotypes in type 1 diabetes and severe hypoglycaemia requiring emergency treatment: a case cohort study.
  67. Early Progression of the Autonomic Dysfunction Observed in Pediatric Type 1 Diabetes Mellitus.
  68. Lipid abnormalities predict progression of renal disease in patients with type 1 diabetes.
  69. Prevalence of diabetic retinopathy and cataract in adult patients with type 1 and type 2 diabetes in Russia.
  70. Type 1 Diabetes Development Requires Both CD4+ and CD8+ T cells and Can Be Reversed by Non-Depleting Antibodies Targeting Both T Cell Populations.

    7 October 2009

  71. Incidence of Childhood Type 1 Diabetes: A Worrying Trend.
  72. Ingestion of Diet Soda before a Glucose Load Augments GLP-1 Secretion.
  73. Effects of Exenatide Alone and in Combination with Daclizumab on Beta Cell Function in Long-Standing Type 1 Diabetes Mellitus.
  74. Efficacy and safety of AIR inhaled insulin compared to insulin lispro in patients with type 1 diabetes mellitus in a 6-month, randomized, noninferiority trial.
  75. Two-year efficacy and safety of AIR inhaled insulin in patients with type 1 diabetes: An open-label randomized controlled trial.
  76. Telomere length predicts all-cause mortality in patients with type 1 diabetes.
  77. A Randomised Placebo Controlled Double Blind Clinical Trial of Cannabis Based Medicinal Product (Sativex) in Painful Diabetic Neuropathy: Depression is a Major Confounding Factor.
  78. Regression of diabetic complications by islet transplantation in the rat.
  79. The International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes--chapter 3: Pig islet product manufacturing and release testing.
  80. Infection With Viruses From Several Families Triggers Autoimmune Diabetes In LEW.1WR1 Rats: Prevention of Diabetes by Maternal Immunization.

    30 September 2009

  81. The July/August 2009 issue of Xenotransplantation focused on porcine islet transplantation as a cure for type 1 diabetes.
  82. A rare haplotype of the vitamin D receptor gene is protective against diabetic nephropathy.
  83. Increased circulating IL-8 is associated with reduced IGF-1 and related to poor metabolic control in adolescents with type 1 diabetes mellitus.
  84. Improving islet transplantation: a road map for a widespread application for the cure of persons with type I diabetes.
  85. Prevention of beta cell dysfunction and apoptosis by adenoviral gene transfer of rat insulin-like growth factor 1. Free full text available in HTML and PDF formats.

    23 September 2009

  86. Use of a cocktail regimen consisting of soluble galectin-1, rapamycin and histone deacetylase inhibitor may effectively prevent type 1 diabetes.
  87. The Diabetes Control and Complications Trial: the gift that keeps giving.
  88. Progression Factors of Carotid Intima-Media Thickness and Plaque in Patients with Long-Term, Early-Onset Type 1 Diabetes Mellitus in Japan: Simultaneous Comparison with Diabetic Retinopathy. Free full text available in PDF format.
  89. Anti-infectious antibodies and autoimmune-associated autoantibodies in patients with type I diabetes mellitus and their close family members.
  90. Factors in serum from type 2 diabetes patients can cause cellular insulin resistance.

    16 September 2009

  91. Closed-Loop Artificial Pancreas Using Subcutaneous Glucose Sensing and Insulin Delivery and a Model Predictive Control Algorithm: Preliminary Studies in Padova and Montpellier. (PDF)
  92. Overnight Closed-Loop Insulin Delivery with Model Predictive Control: Assessment of Hypoglycemia and Hyperglycemia Risk Using Simulation Studies. (PDF)
  93. A Closed-Loop Artificial Pancreas Using Model Predictive Control and a Sliding Meal Size Estimator. (PDF)
  94. Probabilistic Evolving Meal Detection and Estimation of Meal Total Glucose Appearance. (PDF)
  95. Analysis, Modeling, and Simulation of the Accuracy of Continuous Glucose Sensors.
  96. From Genetic Risk Awareness to Overt Type 1 Diabetes: Parental Stress in a Placebo-Controlled Prevention Trial.
  97. Predictive Characteristics of Diabetes-Associated Autoantibodies Among Children With HLA-Conferred Disease Susceptibility in the General Population.
  98. Pancreatic Islet Autoantibodies as Predictors of Type 1 Diabetes in the Diabetes Prevention Trial-Type 1 (DPT-1).
  99. Revisiting infant growth prior to childhood onset type 1 diabetes.
  100. Genetic polymorphisms in genes encoding antioxidant enzymes are associated with diabetic retinopathy in type 1 diabetes.
  101. Blindness in a 25-Year Follow-up of a Population-Based Cohort of Danish Type 1 Diabetic Patients.

    9 September 2009

  102. Increasing incidence of pediatric type 1 diabetes mellitus in Southeastern Wisconsin: relationship with body weight at diagnosis. Free full text available in HTML and PDF formats.
  103. Vitamin D receptor gene polymorphisms and susceptibility to type 1 diabetes in Crete, Greece.
  104. Pancreas transplantation alone in children: a case report.
  105. Lipid disorders in type 1 diabetes.
  106. Elevated Proportions of Recent Thymic Emigrants in Children and Adolescents with Type 1 Diabetes.

    2 September 2009

  107. Generation of pluripotent stem cells from patients with type 1 diabetes. Free full text available in PDF format. See also Researchers Make Insulin-Producing Cells From Adult Skin Cells.
  108. Multinational study in children and adolescents with newly diagnosed type 1 diabetes: association of age, ketoacidosis, HLA status, and autoantibodies on residual beta-cell function and glycemic control 12 months after diagnosis.
  109. Folic acid supplementation normalizes the endothelial progenitor cell transcriptome of patients with type 1 diabetes: a case-control pilot study.
  110. Reduced endogenous secretory receptor for advanced glycation end products (esRAGE) in young people with Type 1 diabetes developing microalbuminuria.
  111. Early predictors of myocardial disease in children and adolescents with type 1 diabetes mellitus.
  112. Cognitive performance, symptoms and counter-regulation during hypoglycaemia in patients with type 1 diabetes and high or low renin-angiotensin system activity.
  113. One hundred one simultaneous pancreas-kidney transplantations: long-term outcomes at a single center.
  114. Use of small donors (<28 kg) for pancreas transplantation.
  115. The Hygiene Hypothesis: Do We Still Believe in It?
  116. Melatonin prolongs islet graft survival in diabetic NOD mice.

    26 August 2009

  117. Epigenetics: deciphering how environmental factors may modify autoimmune type 1 diabetes.
  118. Alleviation of exogenous insulin requirement in type 1 diabetes mellitus after immunoablation and transplantation of autologous hematopoietic stem cells.
  119. Noninvasive radial artery tonometry augmentation index and urinary albumin/creatinine levels in early adolescents with type 1 diabetes mellitus.
  120. Genetic-induced Variations in the GAD65 T-cell Repertoire Governs Efficacy of Anti-CD3/GAD65 Combination Therapy in New-onset Type 1 Diabetes.
  121. No Effect of the Altered-Peptide Ligand NBI-6024 on Beta Cell Residual Function and Insulin Needs in New-Onset Type 1 Diabetes.
  122. TroponinT and proBNP in fetuses of Type 1 diabetic mothers.
  123. Placental structure in type 1 diabetes: relation to fetal insulin, leptin and IGF-I.
  124. Caffeine consumption attenuates neurochemical modifications in the hippocampus of streptozotocin-induced diabetic rats.
  125. The Ectopic Expression of Pax4 in the Mouse Pancreas Converts Progenitor Cells into alpha and Subsequently beta Cells. See also Scientists Find That a Single Gene Can Convert Pancreatic Alpha Cells Into Betas in Lab Mice.

    19 August 2009

  126. Vitamin D Levels in Subjects With and Without Type 1 Diabetes Residing in a Solar Rich Environment.
  127. Association of type 1 diabetes with month of birth among US youth: The SEARCH for Diabetes in Youth Study.
  128. Retinal arterioles have impaired reactivity to hyperoxia in type 1 diabetes.
  129. Thymus-specific deletion of insulin induces autoimmune diabetes.

    12 August 2009

  130. Altered prefrontal glutamate-glutamine-gamma-aminobutyric acid levels and relation to low cognitive performance and depressive symptoms in type 1 diabetes mellitus.
  131. Carotid intima-media thickness and cerebrovascular reactivity in long-term type 1 diabetes mellitus.
  132. C-peptide is internalised in human endothelial and vascular smooth muscle cells via early endosomes.

    5 August 2009

  133. Insulin treatment in IA-2A-positive relatives of type 1 diabetic patients.
  134. Role of insulin autoantibody affinity as a predictive marker for type 1 diabetes in young children with HLA-conferred disease susceptibility.
  135. Is islet autoimmunity related to insulin sensitivity or body weight in children of parents with type 1 diabetes?
  136. Abnormal retinal autoregulation is detected by provoked stimulation with flicker light in well-controlled patients with type 1 diabetes without retinopathy.
  137. Anti-Mullerian hormone and inhibin B levels as markers of premature ovarian aging and transition to menopause in type 1 diabetes mellitus.
  138. Two studies, Vitamin D Status and Cardiometabolic Risk Factors in the United States Adolescent Population, Prevalence and Associations of 25-Hydroxyvitamin D Deficiency in US Children: NHANES 2001–2004, offer advice on supplementing vitamin D.

    29 July 2009

  139. Long-term metabolic control of autoimmune diabetes in spontaneously diabetic nonobese diabetic mice by nonvascularized microencapsulated adult porcine islets.
  140. HbA1c and serum levels of advanced glycation and oxidation protein products in poorly and well controlled children and adolescents with type 1 diabetes mellitus.
  141. Incidence of insulin-requiring diabetes in the US military.
  142. Temporal Trends In Incidence Of Type 1 Diabetes Between 1986 And 2006 In Brazil.
  143. Markers of bone destruction and formation and periodontitis in type 1 diabetes mellitus.

    22 July 2009

  144. Identification of three wheat globulin genes by screening a Triticum aestivum BAC genomic library with cDNA from a diabetes-associated globulin. Free full text available in PDF format.
  145. Progress towards the clinical use of CD3 monoclonal antibodies in the treatment of autoimmunity.
  146. Hypoglycemic and beta cell protective andrographolide analogue for diabetes treatment.
  147. The glutamic acid decarboxylase 65 immunoglobulin G subclass profile differs between adult-onset type 1 diabetes and latent autoimmune diabetes in adults (LADA) up to 3 years after clinical onset.
  148. Mild Fasting Hyperglycemia in a Child: Importance of New Genetic Tools. Also available in PDF format, which includes the referenced tables.
  149. Pigment epithelium-derived factor contributes to insulin resistance in obesity. See also Discovery of Link Between Obesity and Type 2 Opens Path to Possible New Treatment and When Weight Is the Issue, Doctors Struggle Too.

    15 July 2009

  150. Effect of Ingested Interferon-alpha on beta-Cell Function in Children With New-Onset Type 1 Diabetes.
  151. Remission of type 1 diabetes following anti-CD3 antibody treatment and transplantation of embryonic pancreatic precursors.
  152. Preservation of Beta Cell Function in Autoantibody Positive Youth with Diabetes.
  153. Seasonal variation of diagnosis of Type 1 diabetes mellitus in children worldwide.
  154. Maternal Body Mass Index before pregnancy, maternal weight gain during pregnancy, and risk of persistent positivity for multiple diabetes associated autoantibodies in children with the high-risk HLA genotype: The MIDIA study.
  155. Glucagon-Like Peptide-1 Functionalized PEG Hydrogels Promote Survival and Function of Encapsulated Pancreatic beta-Cells.
  156. Functional Brain Connectivity and Neurocognitive Functioning in Patients with Longstanding Type 1 Diabetes Mellitus with and without Microvascular Complications: a Magnetoencephalography Study.
  157. Telomere length and progression of diabetic nephropathy in patients with type 1 diabetes.
  158. Study Links Nitrosamines to Mortality in Diabetes, Other Diseases.

    1 July 2009

  159. Seeding of pancreatic islets into pre-vascularized tissue-engineering chambers.
  160. Inflammation in Diabetic Encephalopathy is Prevented by C-Peptide.

    24 June 2009

  161. Australia's national trends in the incidence of Type 1 diabetes in 0-14-year-olds, 2000-2006.
  162. Incident Dysglycemia and the Progression to Type 1 Diabetes among Participants in the Diabetes Prevention Trial-Type 1.
  163. The effect of glucose variability on the long-term risk of microvascular complications in type 1 diabetes.
  164. Safety and Viability of Microencapsulated Human Islets Transplanted Into Diabetic Humans.
  165. Familial association between type 1 diabetes and other autoimmune and related diseases.
  166. The -174GG interleukin-6 genotype is protective from retinopathy and nephropathy in juvenile onset type 1 diabetes mellitus.

    17 June 2009

  167. The Onset of Diabetes in Three out of Four Sisters: A Japanese Family with Type 1 Diabetes. A Case Report. Free full text available in PDF format.
  168. Pioglitazone might prevent the progression of slowly progressive type 1 diabetes. Free full text available in PDF format.

    10 June 2009

  169. Can childhood viral infection protect from type 1 diabetes?
  170. Protective effects of 1-alpha-hydroxyvitamin D3 on residual beta-cell function in patients with adult-onset latent autoimmune diabetes (LADA).
  171. Long-term glycemic control influences the long-lasting effect of hyperglycemia on endothelial function in type 1 diabetes.
  172. ADA: Fluorescent Intravascular Glucose Sensor Appears Accurate.
  173. Genes play role in glycemic control in type 1 diabetes.

    3 June 2009

  174. Interplay between PTPN22 C1858T polymorphism and cow's milk formula exposure in type 1 diabetes.
  175. Incident Dysglycemia and the Progression to Type 1 Diabetes among Participants in the Diabetes Prevention Trial-Type 1.
  176. Incidence trends for childhood type 1 diabetes in Europe during 1989—2003 and predicted new cases 2005—20: a multicentre prospective registration study. See also Type 1 Diabetes Incidence Jumps 4% Annually in Europe's Youngest.
  177. Incidence and Time Trend of Type 1 and Type 2 Diabetes in Austrian Children 1999-2007.
  178. Prevalence of overweight and obesity in youth with diabetes in USA: the SEARCH for Diabetes in Youth Study.
  179. Circulating endothelial progenitor cells, endothelial function, carotid intima-media thickness and circulating markers of endothelial dysfunction in people with type 1 diabetes without macrovascular disease or microalbuminuria.
  180. Immunoregulatory mechanisms triggered by viral infections protect from type 1 diabetes in mice. Free full text available in HTML and PDF formats.
  181. Changes in autoreactive T cell avidity during type 1 diabetes development.
  182. Lifetime prevalence of comorbid mood disorders in a representative sample of Canadians with type 1 diabetes.
  183. Accelerated Pharmacokinetics and Glucodynamics of Prandial Insulins Injected With Recombinant Human Hyaluronidase. See also Phase 1 Study For Halozyme's Insulin-PH20 Published, Highlights Findings For Faster Acting Insulin Formulations.
  184. Regeneration of the Pancreas in Adult Zebrafish.
  185. Predictors of Study Completion and Withdrawal in a Randomized Clinical Trial of a Pediatric Diabetes Adherence Intervention.
  186. Influence of Early Nutritional Components on the Development of Murine Autoimmune Diabetes.

    27 May 2009

  187. Pathophysiology of type 2 diabetes mellitus in youth: the evolving chameleon. Free full text available in HTML and PDF formats.
  188. Minimally invasive insulin delivery in subjects with type 1 diabetes using hollow microneedles.
  189. A Case-Sibling Assessment of the Association Between Skin Pigmentation and Other Vitamin D-related Factors and Type 1 Diabetes Mellitus.
  190. Adiposity and mortality in type 1 diabetes.
  191. Camel milk as an adjuvant therapy for the treatment of type 1 diabetes: verification of a traditional ethnomedical practice.

    20 May 2009

  192. Treatment of patients with new onset Type 1 diabetes with a single course of anti-CD3 mAb teplizumab preserves insulin production for up to 5 years.
  193. How close are we to developing an alternative to human islet cell transplantation?
  194. In Silico Preclinical Trials: A Proof of Concept in Closed-Loop Control of Type 1 Diabetes.
  195. Pulsatile intravenous insulin therapy: The best practice to reverse diabetes complications?
  196. Pulse pressure and cardiovascular autonomic neuropathy according to duration of type 1 diabetes.

    13 May 2009

  197. Improved glycemic control with intraperitoneal versus subcutaneous insulin in type 1 diabetes. A randomized controlled trial.
  198. Pig-to-nonhuman primate islet xenotransplantation.

    6 May 2009

  199. GAD65 vaccination: 5 years of follow-up in a randomised dose-escalating study in adult-onset autoimmune diabetes. Free full text available in PDF format.
  200. New prospects for immunotherapy at diagnosis of type 1 diabetes.
  201. Elevated Triglycerides Correlate with Progression of Diabetic Neuropathy.
  202. Serum uric acid as a predictor for development of diabetic nephropathy in type 1 diabetes - an inception cohort study.
  203. Epidemiology and clinical characteristics of thyroid dysfunction in children and adolescents with type 1 diabetes.
  204. Staphylococcus aureus nasal carriage might be associated with vitamin D receptor polymorphisms in type 1 diabetes.

    29 April 2009

  205. Diabetic Subjects Diagnosed Through the Diabetes Prevention Trial–Type 1 (DPT-1) Are Often Asymptomatic With Normal A1C at Diabetes Onset.
  206. The Presence And Severity Of Chronic Kidney Disease Predicts All-Cause Mortality In Type 1 Diabetes.
  207. Infection and type 1 diabetes mellitus - a two edged sword?
  208. Treatment of diabetes by transplantation of drug-inducible insulin-producing gut cells.
  209. Engineering functional islets from cultured cells.
  210. Pig embryonic pancreatic tissue as a source for transplantation in diabetes: transient treatment with anti-LFA1, anti-CD48 and FTY720 enables long term graft maintenance in mice with only mild ongoing immunosuppression.

    22 April 2009

  211. Etanercept Treatment in Children with New Onset Type 1 Diabetes: Pilot Randomized, Placebo-Controlled, Double Blind Study.
  212. Lower bone mineral density in children with type 1 diabetes is associated with poor glycemic control and higher serum ICAM-1 and urinary isoprostane levels.
  213. Incidence of type 1 diabetes mellitus and associated complications among children and young adults: results from Karnataka Diabetes Registry 1995-2008.
  214. Male predominance of congenital malformations in infants of women with type 1 diabetes.
  215. Evaluation of the chronic complications of diabetes in a high fructose diet in rats.

    15 April 2009

  216. C-Peptide Levels and Insulin Independence Following Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation in Newly Diagnosed Type 1 Diabetes Mellitus. See also Stem Cells Appear Effective for Type 1 Diabetes, Study: Stem Cells May Reverse Type 1 Diabetes and Transplants help Type 1 diabetics skip insulin, as well as related report Pancreatic Islet Demand for Diabetes Research Outruns Supply.
  217. Birth Weight, Early Weight Gain, and Subsequent Risk of Type 1 Diabetes: Systematic Review and Meta-Analysis.

    8 April 2009

  218. Pancreatic function assessment in type 1 diabetes mellitus patients according to disease duration. Free Portuguese language full text available in HTML and PDF formats.
  219. The type 1 diabetes protective HLA DQB1*0602 allele is less frequent in gestational diabetes mellitus.
  220. Potential of small molecule protein tyrosine kinase inhibitors as immuno-modulators and inhibitors of the development of Type 1 diabetes.
  221. Prevalence of polyglandular autoimmune syndrome in patients with diabetes mellitus type 1.

    1 April 2009

  222. Anti-CD3 mAbs for treatment of type 1 diabetes.
  223. Advances in Type 1 diabetes therapeutics: immunomodulation and beta-cell salvage.
  224. Antibiotic Use and Type 1 Diabetes in Childhood.
  225. Can pancreatic duct-derived progenitors be a source of islet regeneration?
  226. Improved T cell assay for identification of Type 1 diabetes patients.
  227. CD4+ CD25+ T cells control autoimmunity in the absence of B cells.
  228. Microchimerism in type 1 diabetes.

    25 March 2009

  229. Early nephropathy in type 1 diabetes: the importance of early renal function decline.
  230. Geographical variability of the incidence of Type 1 diabetes in subjects younger than 30 years in Catalonia, Spain.
  231. Double Diabetes: A Mixture of Type 1 and Type 2 Diabetes in Youth.
  232. Latent autoimmune diabetes of adulthood (LADA): an often misdiagnosed type of diabetes mellitus.
  233. Treatment of insulin dependent diabetes mellitus with intravascular transplantation of pancreatic islet cells without immunosuppressive therapy.

    18 March 2009

  234. Diabetic retinal neurodegeneration is associated with mitochondrial oxidative stress and is improved by angiotensin receptor blocker in a model that combines hypertension and diabetes.
  235. Blood glucose levels regulate pancreatic beta-cell proliferation during experimentally-induced and spontaneous autoimmune diabetes in mice. Free full text available in HTML and PDF formats (link to PDF on full text page).
  236. Prevalence of vitamin D receptor gene polymorphisms FokI and BsmI in Brazilian Type 1 diabetes and their relation to beta cell autoimmunity and to remaining beta cell function.
  237. Neurogenin3 Is Sufficient for Transdetermination of Hepatic Progenitor Cells into Neo-Islets In Vivo but Not Transdifferentiation of Hepatocytes. See also Stem cells crucial to diabetes cure in mice and Diabetes cure a step closer after liver used to regulate blood sugar.

    11 March 2009

  238. The prevalence of enteroviral capsid protein vp1 immunostaining in pancreatic islets in human type 1 diabetes. Free full text available in HTML and PDF formats. See also Virus 'triggers child diabetes', Common Virus Linked to Type 1 Diabetes in Children and Vaccine 'could stop diabetes'.
  239. Can We Learn From Viruses How to Prevent Type 1 Diabetes?
  240. Early infant feeding and type 1 diabetes.
  241. Immune modulation in type 1 diabetes mellitus using DiaPep277: a short review and update of recent clinical trial results.
  242. Therapy with GAD in diabetes.
  243. Screening for Associated Autoimmunity in Children and Adolescents with Type 1 Diabetes Mellitus (T1DM).
  244. Recurrent Antecedent Hypoglycemia Alters Neuronal Oxidative Metabolism in Vivo.

    4 March 2009

  245. Cellular and physiological effects of C-peptide.
  246. The geospatial relation between UV solar radiation and type 1 diabetes in Newfoundland.
  247. Rapamycin induces autophagy in islets: relevance in islet transplantation.
  248. 25 February 2009

  249. Pregnancy-induced rise in serum C-peptide concentrations in women with type 1 diabetes.
  250. C-peptide protects against microvascular complications in Type 1 diabetes refers to Fasting plasma C-peptide and micro- and macrovascular complications in a large clinic-based cohort of type 1 diabetic people, already reported.
  251. Cerebrovascular reactivity, IMT and nephropathy presence in patients with type 1 diabetes.
  252. A national database on children and adolescent with diabetes (e-DiCARE): results from April 2006 to June 2007 [in Malaysia].
  253. Cryopreserved agarose-encapsulated islets as bioartificial pancreas: a feasibility study.
  254. Predictors of Overweight during Childhood in Offspring of Parents with Type 1 Diabetes.
  255. Culture-independent identification of gut bacteria correlated with the onset of diabetes in a rat model.

    18 February 2009

  256. Medium Chain Fatty Acids Improve Cognitive Function in Intensively Treated Type 1 Diabetic Patients and Support in vitro Synaptic Transmission During Acute Hypoglycemia.
  257. Avosentan Reduces Albumin Excretion in Diabetics with Macroalbuminuria. See also Experimental Endothelin Antagonist Reduces Diabetic Kidney Disease.
  258. Specificity of islet cell autoantibodies and coexistence with other organ specific autoantibodies in type 1 diabetes mellitus.
  259. Erythropoietin during hypoglycaemia in type 1 diabetes: Relation to basal renin-angiotensin system activity and cognitive function.
  260. Exendin-4 treatment of nonobese diabetic mice increases beta-cell proliferation and fractional insulin reactive area.
  261. Immune markers of disease and therapeutic intervention in type 1 diabetes.
  262. Towards a curative therapy in type 1 diabetes: remission of autoimmunity, maintenance and augmentation of beta cell mass.
  263. Analytical Methods for the Retrieval and Interpretation of Continuous Glucose Monitoring Data in Diabetes.
  264. Graphical and Numerical Evaluation of Continuous Glucose Sensing Time Lag.

    11 February 2009

  265. A Feedforward-Feedback Glucose Control Strategy for Type 1 Diabetes Mellitus. Free full text available in HTML and PDF formats.
  266. The role of toll-like receptor pathways in the mechanism of type 1 diabetes.
  267. Perinatal risk factors in young adult-onset type 1 and type 2 diabetes - a population-based case-control study.
  268. Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of A-beta oligomers. Free full text available in PDF format. See also Insulin is a Possible New Treatment for Alzheimer's, Insulin May Protect Mind, Memory; Diabetes Drugs Protect Against Alzheimer's-Related Memory Damage, and A Surprising Link Between Diabetes and Alzheimer's.

    28 January 2009

  269. Insulin analogues display IGF-I-like mitogenic and anti-apoptotic activities in cultured cancer cells. Free full text available in HTML and PDF formats. See also Commentary - Insulin analogues: fears, facts and fantasies, also available in PDF format.
  270. Human cord blood stem cell-modulated regulatory T lymphocytes reverse the autoimmune-caused type 1 diabetes in nonobese diabetic (NOD) mice. Free full text available in HTML and PDF formats.
  271. The Wisconsin Epidemiologic Study of Diabetic Retinopathy XXIII: The Twenty-five-Year Incidence of Macular Edema in Persons with Type 1 Diabetes.
  272. Long-term hyperglycaemia impairs vascular smooth muscle cell function in women with type 1 diabetes mellitus.
  273. Plasma advanced glycation endproduct, methylglyoxal-derived hydroimidazolone is elevated in young, complication-free patients with Type 1 diabetes.
  274. Detection of nocturnal hypoglycemic episodes (natural occurrence) in children with Type 1 diabetes using an optimal Bayesian neural network algorithm.

    21 January 2009

  275. GAD-Alum Treatment Seems Effective in Slowing Residual Beta-Cell Function Loss. Free full text available in PDF format.
  276. Central nervous system function in youth with type 1 diabetes 12 years after disease onset.
  277. Selective Loss of Inner Retinal Layer Thickness in Type 1 Diabetic Patients with Minimal Diabetic Retinopathy.
  278. Rapamycin Prevents and Breaks the Anti-CD3–Induced Tolerance in NOD Mice.
  279. The protective effect of simvastatin against low dose streptozotocin induced type 1 diabetes in mice is independent of inhibition of HMG-CoA reductase.
  280. Bone inflammation and altered gene expression with type I diabetes early onset.
  281. Efficient differentiation of insulin-producing cells from skin-derived stem cells.
  282. Encapsulated porcine islet transplantation: an evolving therapy for the treatment of type I diabetes.

    14 January 2009

  283. Correction of diabetes in primates by macroencapsulated pig islets.
  284. Prolonged survival of pig islets xenograft by adenovirus-mediated expression of either the membrane-bound human FasL or the human decoy Fas antigen gene.
  285. Intraperitoneal insulin infusion versus islet transplantation: comparative study in patients with type 1 diabetes.
  286. Genome-wide scan for linkage to type 1 diabetes in 2,496 multiplex families from the Type 1 Diabetes Genetics Consortium.
  287. Intranasal Insulin Ameliorates Experimental Diabetic Neuropathy.
  288. The incremental value of the pancreas allograft to the survival of Simultaneous Pancreas-Kidney transplant recipients.
  289. Exercise Training During Diabetes Attenuates Cardiac Ryanodine Receptor Dysregulation.
  290. Analysis of islet inflammation in human type 1 diabetes.
  291. Childhood BMI trajectories and the risk of developing young adult-onset diabetes.

    7 January 2009

  292. Can We Learn From Viruses How to Prevent Type 1 Diabetes?
  293. The Environmental Determinants of Diabetes in the Young (TEDDY) Study.
  294. Diabetogenic effects of the most prevalent enteroviruses in Finnish sewage.
  295. Variations in incidence of type 1 diabetes in different municipalities of stockholm.
  296. Risk conferred by HLA-DR and DQ for type 1 diabetes in 0-35-year age group in Sweden.
  297. Exendin-4 therapy in NOD mice with new-onset diabetes increases regulatory T cell frequency.
  298. Leaking gut in type 1 diabetes.
  299. Persistence of residual beta cells and islet autoimmunity during increasing duration of diabetes in NOD mice and experimental approaches toward reversing new-onset disease with bioactive peptides.
  300. Antigen specific treatment for the inhibition and remission of type 1 diabetes.
  301. Review series on helminths, immune modulation and the hygiene hypothesis: how might infection modulate the onset of type 1 diabetes?
  302. Is population mixing associated with childhood type 1 diabetes in Canterbury, New Zealand?
  303. Role of increased ROS dissipation in prevention of T1D.
  304. Effect of Parental Type 2 Diabetes on Offspring With Type 1 Diabetes.

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