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Research News From 2011

    28 December 2011

  1. How does age at onset influence the outcome of autoimmune diseases? Free full text available in HTML and PDF formats.
  2. Results of pancreas transplantation alone with special attention to native kidney function and proteinuria in type 1 diabetes patients.
  3. Near Normalization of Metabolic and Functional Features of the Central Nervous System in Type 1 Diabetic Patients With End-Stage Renal Disease After Kidney-Pancreas Transplantation.

    21 December 2011

  4. Long-Lasting Immune Responses 4 Years after GAD-Alum Treatment in Children with Type 1 Diabetes. Free full text available in HTML and PDF formats.
  5. Striated muscle as implantation site for transplanted pancreatic islets. Free full text available in HTML and PDF formats.
  6. Glucagon in the Pathogenesis of Hypoglycemia and Hyperglycemia in Diabetes.
  7. The D-Lightful Vitamin D for Child Health.

    14 December 2011

  8. Increase in the incidence of type 1 diabetes in Israeli children following the Second Lebanon War.
  9. Update from the Faustman Lab: Moving Forwrd to Phase 2.

    7 December 2011

  10. FDA outlines flexible approaches for artificial pancreas system clinical trials, product approvals See also JDRF Encouraged By Draft FDA Artificial Pancreas Guidance and FDA Issues Artificial Pancreas Guidance Document.
  11. Intravital imaging of CTLs killing islet cells in diabetic mice. See also a Jolla Institute researchers provide world's first view of Type 1 diabetes as it unfolds.
  12. Type 1 diabetes in Cheshire: Cardiometabolic risk factor trends (2004-2009).
  13. End-stage nephropathy in Type 1-diabetes mellitus - Kidney transplantation alone or combined with Islet or pancreas transplantation?
  14. Improved Postprandial Glycemic Control in Patients with Type 2 Diabetes from Subcutaneous Injection of Insulin Lispro with Hyaluronidase.
  15. Reversal of diabetes by the creation of neo-islet tissues into a subcutaneous site using islet cell sheets.

    30 November 2011

  16. Maternal Serum Levels of 25-Hydroxy-Vitamin D During Pregnancy and Risk of Type 1 Diabetes in the Offspring.
  17. Impaired diffusing capacity for carbon monoxide in children with type 1 diabetes: is this the first sign of long-term complications?
  18. Proinsulin, GLP-1, and glucagon are associated with partial remission in children and adolescents with newly diagnosed type 1 diabetes.
  19. Case report: type 1 diabetes in monozygotic quadruplets.

    23 November 2011

  20. An important minority of prediabetic first-degree relatives of type 1 diabetic patients derives from seroconversion to persistent autoantibody positivity after 10 years of age.

    16 November 2011

  21. Markedly reduced rate of diabetic ketoacidosis at onset of type 1 diabetes in relatives screened for islet autoantibodies.
  22. Closed-loop insulin delivery for treatment of type 1 diabetes. Free full text available in PDF format.
  23. Persistent glucose transporter expression on pancreatic beta cells from longstanding type 1 diabetic individuals.
  24. Age-corrected Beta cell mass following onset of type 1 diabetes mellitus correlates with plasma C-Peptide in humans. Free full text available in HTML and PDF formats.
  25. Diabetes technology and treatments in the paediatric age group.
  26. Self-reported lower respiratory tract infections and development of islet autoimmunity in children with the type 1 diabetes high-risk HLA genotype: the MIDIA study.
  27. Metabolic function of a suboptimal transplanted islet mass in non-human primates on rapamycin monotherapy.
  28. Enteroviruses and type 1 diabetes.
  29. Vaccination and risk of type 1 diabetes mellitus in active component U.S. Military, 2002-2008.
  30. Signatures of Environmental Genetic Adaptation Pinpoint Pathogens as the Main Selective Pressure through Human Evolution. Free full text available in HTML and PDF formats.

    9 November 2011

  31. Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes. Free full text available in HTML and PDF formats (link in HTML full text).
  32. Current status of immunomodulatory and cellular therapies in preclinical and clinical islet transplantation. Free full text available in HTML and PDF formats.
  33. Otelixizumab in the treatment of Type 1 diabetes mellitus.
  34. Association of Epilepsy and Type 1 Diabetes Mellitus in Children and Adolescents: Is There an Increased Risk for Diabetic Ketoacidosis?
  35. High levels of immunoglobulin E and a continuous increase in immunoglobulin G and immunoglobulin M by age in children with newly diagnosed type 1 diabetes.
  36. Identification of Small Molecule Inhibitors that Suppress Cytokine-Induced Apoptosis in Human Pancreatic Islet Cells. Free full text available in HTML and PDF formats.

    2 November 2011

  37. Age- and islet autoimmunity-associated differences in amino Acid and lipid metabolites in children at risk for type 1 diabetes.
  38. Helicobacter pylori infection might be responsible for the interconnection between type 1 diabetes and autoimmune thyroiditis.
  39. Metabolic Control and Bone Health in Adolescents with Type 1 Diabetes.

    19 October 2011

  40. Real-Time Adaptive Models for the Personalized Prediction of Glycemic Profile in Type 1 Diabetes Patients.

    12 October 2011

  41. U-100, pH-Neutral Formulation of VIAject(®) : Faster Onset of Action than Insulin Lispro in Patients with Type 1 Diabetes.
  42. Exposure to the Viral By-Product dsRNA or Coxsackievirus B5 Triggers Pancreatic Beta Cell Apoptosis via a Bim / Mcl-1 Imbalance. Free full text available in HTML and PDF formats.
  43. Circulating Endothelial Progenitor Cells and Large Artery Structure And Function In Young Subjects With Uncomplicated Type 1 Diabetes. Free full text available in PDF format.
  44. Sensitization to Gliadin Induces Moderate Enteropathy and Insulitis in Nonobese Diabetic-DQ8 Mice.
  45. Neonatal jaundice is associated with a small increase in the risk of childhood type 1 diabetes: a meta-analysis of observational studies.

    5 October 2011

  46. Automatic Learning Algorithm for the MD-Logic Artificial Pancreas System.
  47. Reduced Prevalence of Diabetes Ketoacidosis at Diagnosis of Type 1 Diabetes in Young Children Participating in Longitudinal Follow-Up.
  48. Reclassification of diabetes type in pediatric patients initially classified as type 2 diabetes mellitus: 15 years follow-up using routine data from the German/Austrian DPV database.

    28 September 2011

  49. Prospectively Determined Impact of Type 1 Diabetes on Brain Volume During Development.
  50. Human enterovirus infections in children at increased risk for type 1 diabetes: the Babydiet study.
  51. Seasonal variation of vitamin D and HbA(1c) levels in patients with type 1 diabetes mellitus in the Middle East. Free full text available in HTML and PDF formats.
  52. Vitamin D Insufficiency in Diabetic Retinopathy. Free full text available in PDF format.

    21 September 2011

  53. Long-Term Metabolic and Immunological Follow-Up of Nonimmunosuppressed Patients With Type 1 Diabetes Treated With Microencapsulated Islet Allografts.
  54. Interaction of enterovirus infection and Cow's milk-based formula nutrition in type 1 diabetes-associated autoimmunity.
  55. EASD: Closed-loop System on Par With Open-loop for Glucose Control.
  56. C-peptide in the classification of diabetes in children and adolescents.
  57. Recurrence of autoimmunity in pancreas transplant patients: research update.
  58. Acute Hypoglycemia Decreases Myocardial Blood Flow Reserve in Patients With Type 1 Diabetes Mellitus and in Healthy Humans.
  59. Healthy first degree relatives of patients with type 1 diabetes exhibit significant differences in basal gene expression pattern of immunocompetent cells compared to controls: expression pattern as predeterminant of autoimmune diabetes.
  60. Pancreatitis, Pancreatic, and Thyroid Cancer With Glucagon-Like Peptide-1–Based Therapies. Free full text available in HTML and PDF formats. See also Two diabetes drugs possibly linked to pancreatitis, cancer, UPDATE: Research linking two diabetes drugs to cancer spawns debate, and Who Defends Those Lilly & Novo Nordisk Diabetes Meds?

    15 September 2011

  61. C-Peptide Response and HLA Genotypes in Subjects With Recent-Onset Type 1 Diabetes After Immunotherapy With DiaPep277.
  62. Effect of rituximab on human in vivo antibody immune responses.
  63. Advanced Glycation End Products Are Direct Modulators of beta-Cell Function.
  64. A Longitudinal Study of GAD65 and ICA512 Autoantibodies During the Progression to Type 1 Diabetes in Diabetes Prevention Trial–Type 1 (DPT-1) Participants.

    7 September 2011

  65. Closed-loop in children with type 1 diabetes: Specific challenges.
  66. A Stepwise Approach toward Closed-Loop Blood Glucose Control for Intensive Care Unit Patients: Results from a Feasibility Study in Type 1 Diabetic Subjects Using Vascular Micro dialysis with Infrared Spectrometry and a Model Predictive Control Algorithm.
  67. Family history of diabetes and distribution of class II HLA genotypes in children with newly diagnosed type 1 diabetes: effect on diabetic ketoacidosis.
  68. Early Neural and Vascular Changes in the Adolescent Type 1 and Type 2 Diabetic Retina.

    31 August 2011

  69. Donor Islet Endothelial Cells in Pancreatic Islet Revascularization.
  70. Genetic Analysis of Adult-Onset Autoimmune Diabetes.
  71. In August 2011, the Institute of Medicine issued a report on Adverse Effects of Vaccines: Evidence and Causality and concluded that evidence favors rejection of a causal relationship between the MMR and DTaP vaccines and type 1 diabetes.
  72. Immunological Applications of Stem Cells in Type 1 Diabetes.
  73. The possible role of esRAGE and sRAGE in the natural history of diabetic nephropathy in childhood.

    24 August 2011

  74. No association of vitamin D intake or 25-hydroxyvitamin D levels in childhood with risk of islet autoimmunity and type 1 diabetes: the Diabetes Autoimmunity Study in the Young (DAISY).
  75. The epidemic of type 1 diabetes: what is it telling us?
  76. 2011 Update: antigen-specific therapy in type 1 diabetes.
  77. A prevascularized tissue engineering chamber supports growth and function of islets and progenitor cells in diabetic mice.
  78. Pervasive Sharing of Genetic Effects in Autoimmune Disease. Free full text available in HTML and PDF formats (PDF link on HTML full text page).
  79. High levels of oxidized LDL in circulating immune complexes are associated with increased odds of developing abnormal albuminuria in Type 1 diabetes.
  80. Lung functions in poorly controlled type 1 Saudi diabetic children and adolescents.
  81. UF expert: In the quest to cure Type 1 diabetes, scientists must develop better research standards.

    17 August 2011

  82. Reduced Serum Vitamin D-Binding Protein Levels Are Associated With Type 1 Diabetes.
  83. Rituximab Selectively Suppresses Specific Islet Antibodies.
  84. Differentiation of PDX1 gene-modified human umbilical cord mesenchymal stem cells into insulin-producing cells in vitro.
  85. Surface camouflage of pancreatic islets using 6-arm-PEG-catechol in combined therapy with tacrolimus and anti-CD154 monoclonal antibody for xenotransplantation.
  86. Incidence rate trends in childhood Type 1 diabetes in Yorkshire, UK 1978-2007: effects of deprivation and age at diagnosis in the south Asian and non-south Asian populations.

    10 August 2011

  87. Prediction model for the incidence and prevalence of type 1 diabetes in childhood and adolescence: evidence for a cohort-dependent increase within the next two decades in Germany.
  88. Pathogenesis of type 1 diabetes: implications for incidence trends.
  89. Epidemiology of childhood type 1 diabetes mellitus: lessons from central and eastern European data.
  90. Phase I (Safety) Study of Autologous Tolerogenic Dendritic Cells in Type 1 Diabetic Patients.

    3 August 2011

  91. Pig-to-Nonhuman Primates Pancreatic Islet Xenotransplantation: An Overview.
  92. Type 1 diabetes mellitus and major depressive disorder: evidence for a biological link.
  93. Therapeutic Impact of Leptin on Diabetes, Diabetic Complications, and Longevity in Insulin-Deficient Diabetic Mice.

    27 July 2011

  94. Being born in Sweden increases the risk for type 1 diabetes - a study of migration of children to Sweden as a natural experiment.
  95. Current state of type 1 diabetes immunotherapy: incremental advances, huge leaps, or more of the same?
  96. Increased Numbers of Low-Oxygenated Pancreatic Islets After Intraportal Islet Transplantation.

    20 July 2011

  97. Prevention of murine autoimmune diabetes by CCL22-mediated Treg recruitment to the pancreatic islets. See also Researchers identify process that prevents type 1 diabetes from progressing.
  98. Development of Autoantibodies in the TrialNet Natural History Study.
  99. Generation of pancreatic insulin-producing cells from rhesus monkey induced pluripotent stem cells.
  100. Association of Urinary Type IV Collagen With GFR Decline in Young Patients With Type 1 Diabetes.
  101. Protection against Autoimmune Diabetes by Silkworm-Produced GFP-Tagged CTB-Insulin Fusion Protein.

    13 July 2011

  102. Fisetin lowers methylglyoxal dependent protein glycation and limits the complications of diabetes. Free full text available in HTML and PDF formats (PDF link within full text article).
  103. Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial.
  104. Teplizumab for treatment of type 1 diabetes (Protégé study): 1-year results from a randomised, placebo-controlled trial.
  105. Predictors of associated autoimmune diseases in families with type 1 diabetes: results from the Type 1 Diabetes Genetics Consortium.
  106. How viral infections enhance or prevent type 1 diabetes-from mouse to man.
  107. C-reactive protein promotes diabetic kidney disease in a mouse model of type 1 diabetes.
  108. Use of a novel fluorescent glucose sensor in volunteer subjects with type 1 diabetes mellitus.
  109. Reduction of Postprandial Glycemic Excursions in Patients with Type 1 Diabetes: A Novel Human Insulin Formulation versus a Rapid-Acting Insulin Analog and Regular Human Insulin.

    29 June 2011

  110. Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial. See also ADA: Type 1 Diabetes Vaccine Fails to Show Benefit.
  111. Improvements in the Life Expectancy of Type 1 Diabetes: The Pittsburgh Epidemiology of Diabetes Complications Study. See also Life Expectancy Improves for Type 1 Diabetics.
  112. Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial. See also ADA: Biologic Slows Type 1 Diabetes.
  113. Uncoupling of Proliferation and Cytokines From Suppression Within the CD4+CD25+Foxp3+ T–Cell Compartment in the 1st Year of Human Type 1 Diabetes.
  114. ADA: FDA Artificial Pancreas Initiative InFocus.

    21 June 2011

  115. Incidence of Type 1 Diabetes in Sweden Among Individuals Aged 0–34 Years, 1983–2007: An analysis of time trends.
  116. The gut as a regulator of early inflammation in type 1 diabetes.
  117. Non-invasive retinal testing may predict retinopathy explains on Retinal Vascular Geometry Predicts Incident Retinopathy in Young People With Type 1 Diabetes, previously reported.
  118. Proliferative retinopathy predicts nephropathy: a 25-year follow-up study of type 1 diabetic patients.
  119. Phase I (Safety) Study of Autologous Tolerogenic Dendritic Cells in Type 1 Diabetic Patients.

    15 June 2011

  120. Early feeding and risk of type 1 diabetes: experiences from the Trial to Reduce Insulin-dependent diabetes mellitus in the Genetically at Risk (TRIGR). See also New Study Shows Infant Formula Linked to Childhood Diabetes.
  121. Thymic Self-Antigen Expression for the Design of a Negative/Tolerogenic Self-Vaccine against Type 1 Diabetes. Free full text available in HTML and PDF formats.
  122. Antigen-based immune therapeutics for type 1 diabetes: magic bullets or ordinary blanks? Free full text available in HTML and PDF formats.
  123. Type I diabetes-associated tolerogenic properties of interleukin-2. Free full text available in HTML and PDF formats.
  124. Recurrence of Autoimmunity Following Pancreas Transplantation.
  125. Progressive Erosion of beta-Cell Function Precedes the Onset of Hyperglycemia in the NOD Mouse Model of Type 1 Diabetes.
  126. JDRF to Support Selecta's Development of Tolerogenic Type 1 Diabetes Vaccine.

    8 June 2011

  127. The Feasibility of Detecting Neuropsychologic and Neuroanatomic Effects of Type 1 Diabetes in Young Children.
  128. What causes type 1 diabetes? Lessons from animal models.
  129. Etiological Approach to Characterization of Diabetes Type: The SEARCH for Diabetes in Youth Study.
  130. Skin Intrinsic Fluorescence Is Associated With Hemoglobin A1c and Hemoglobin Glycation Index but Not Mean Blood Glucose in Children With Type 1 Diabetes.
  131. Defective Differentiation of Regulatory FoxP3+ T Cells by Small-Intestinal Dendritic Cells in Patients With Type 1 Diabetes.

    1 June 2011

  132. Serum adiponectin concentration is a positive predictor of all-cause and cardiovascular mortality in type 1 diabetes.
  133. Soluble receptor for AGE (RAGE) is a novel independent predictor of all-cause and cardiovascular mortality in type 1 diabetes.

    25 May 2011

  134. Long-Term Outcome of Individuals Treated With Oral Insulin: Diabetes Prevention Trial–Type 1 (DPT-1) oral insulin trial.
  135. First-degree relatives of persons with type 1 diabetes: insulin resistance and enterovirus infection are associated with different patterns of islet cell autoimmunity.
  136. Prevalence and characteristics of diabetes among Somali children and adolescents living in Helsinki, Finland.
  137. Association between vitamin D receptor gene polymorphisms and type 1 diabetes mellitus in Iranian population.
  138. Gut peptide hormones and paediatric type 1 diabetes mellitus.
  139. Retinal Vascular Geometry Predicts Incident Retinopathy in Young People With Type 1 Diabetes.
  140. Diabetes Linked to Premature Death From Vascular Disease, Other Causes.
  141. Amelioration of type I diabetes-induced osteoporosis by parathyroid hormone is associated with improved osteoblast survival.

    18 May 2011

  142. The Feasibility of Detecting Neuropsychologic and Neuroanatomic Effects of Type 1 Diabetes in Young Children.
  143. Age of Islet Autoantibody Appearance and Mean Levels of Insulin, But Not GAD or IA-2 Autoantibodies, Predict Age of Diagnosis of Type 1 Diabetes: Diabetes Autoimmunity Study in the Young.
  144. Blue eyes and fair skin as risk factors for type 1 diabetes.
  145. Increased Accumulation of Skin Advanced Glycation End Products Is Associated with Microvascular Complications in Type 1 Diabetes.
  146. Predictors of microvascular complications in type 1 diabetic patients at onset: The role of metabolic memory.
  147. The Future of Basal Insulin Supplementation.
  148. Evaluating Rate of Change as an Index of Glycemic Variability, Using Continuous Glucose Monitoring Data.

    11 May 2011

  149. Postprandial and Fasting Hepatic Glucose Fluxes in Longstanding Type 1 Diabetes.
  150. Impact of type 1 diabetes and body weight status on cardiovascular risk factors in adolescent children.

    4 May 2011

  151. Association between environmental factors and risk of type 1 diabetes - a case-control study.
  152. What is the role of human contamination by environmental chemicals in the development of type 1 diabetes?
  153. Persistently autoantibody negative (PAN) type 1 diabetes mellitus in children.
  154. Preliminary studies related to anti-interleukin-1beta therapy in children with newly diagnosed type 1 diabetes.
  155. Autoantigen based vaccines for type 1 diabetes.
  156. Use of a precious resource: Parental decision making about using autologous umbilical cord blood in studies involving young children with type 1 diabetes.
  157. A closed-loop artificial pancreas based on risk management.
  158. CD40-Specific Costimulation Blockade Enhances Neonatal Porcine Islet Survival in Nonhuman Primates.
  159. Pancreatic beta Cell Identity Is Maintained by DNA Methylation-Mediated Repression of Arx. See also New study shows it may be possible to turn pancreatic cells into insulin producers in people with type 1 diabetes.
  160. High fat diet protects BB/OK rats from developing type 1 diabetes.

    27 April 2011

  161. Sex-related differences in the long-term risk of microvascular complications by age at onset of type 1 diabetes.
  162. Pirfenidone for Diabetic Nephropathy. See also Antifibrotic May Slow Diabetic Nephropathy.
  163. Reversal of Diabetic Nephropathy by a Ketogenic Diet. See also Diet 'can reverse kidney failure' in mice with diabetes and Diet may 'reverse kidney failure' in diabetics.
  164. Primary Dietary Intervention Study to Reduce the Risk of Islet Autoimmunity in Children at Increased Risk for Type 1 Diabetes - The BABYDIET study.
  165. Correlation between insulin requirements and anti-galactose antibodies in patients with type 1 diabetes transplanted with neonatal pig islets.
  166. Differential Effect of Low-Dose Aspirin for Primary Prevention of Atherosclerotic Events in Diabetic Management.
  167. Future Acceptance of an Artificial Pancreas in Adults with Type 1 Diabetes.
  168. Impact of Intranasal Insulin on Insulin Antibody Affinity and Isotypes in Young Children With HLA-Conferred Susceptibility to Type 1 Diabetes.

    20 April 2011

  169. Overnight closed loop insulin delivery (artificial pancreas) in adults with type 1 diabetes: crossover randomised controlled studies. Free full text available in HTML and PDF formats. See also Artificial Pancreas More Effective at Night.
  170. Free fatty acids level may effect a residual insulin secretion in type 1 diabetes.
  171. Peptide-MHC-based nanovaccines for the treatment of autoimmunity: a "one size fits all" approach?
  172. Oral Anti-CD3 Monoclonal Antibody Delays Diabetes in Non-obese Diabetic (NOD) Mice: Effects on Pregnancy and Offspring - A Preliminary Report.
  173. Anti-CD3 mAb treatment cures PDL1-/-.NOD mice of diabetes but precipitates fatal myocarditis.

    13 April 2011

  174. A Recent Survey Confirms the Efficacy and the Safety of Implanted Insulin Pumps During Long-Term Use in Poorly Controlled Type 1 Diabetes Patients.
  175. Insulin action in adipose tissue in type 1 diabetes. Free full text available in HTML and PDF formats.
  176. Decreased cortical connectivity and information flow in type 1 diabetes.

    6 April 2011

  177. Leptin Therapy Reverses Hyperglycemia in Mice With Streptozotocin-Induced Diabetes, Independent of Hepatic Leptin Signaling.
  178. Protection From Retinopathy and Other Complications in Patients With Type 1 Diabetes of Extreme Duration - The Joslin 50-Year Medalist Study. Free full text available in HTML and PDF formats.
  179. Altered inflammatory, oxidative, and metabolic responses to exercise in pediatric obesity and type 1 diabetes.
  180. Eye Complications and Markers of Morbidity and Mortality in Long-term Type 1 Diabetes.

    30 March 2011

  181. Microvascular complications assessment in adolescents with 2- to 5-yr duration of type 1 diabetes from 1990 to 2006.
  182. Early introduction of root vegetables in infancy associated with advanced beta-cell autoimmunity in young children with human leukocyte antigen-conferred susceptibility to Type 1 diabetes.
  183. Erythrocyte membrane omega-3 fatty acid levels and omega-3 fatty acid intake are not associated with conversion to type 1 diabetes in children with islet autoimmunity: The Diabetes Autoimmunity Study in the Young (DAISY).
  184. Preimplantation factor (PIF) analog prevents type I diabetes mellitus (TIDM) development by preserving pancreatic function in NOD mice.
  185. Inherited Variation in Vitamin D Genes Is Associated With Predisposition to Autoimmune Disease Type 1 Diabetes.
  186. Onset features and subsequent clinical evolution of childhood diabetes over several years.
  187. Assessment of skin autofluorescence as a marker of advanced glycation end product accumulation in type 1 diabetes. Free full text in PDF available via link at the Polish Archives of Internal Medicine web site.
  188. Increased Fat Mass and Cardiac Septal Hypertrophy in Newborn Infants of Mothers with Well-Controlled Diabetes during Pregnancy.

    23 March 2011

  189. HLA Genes, Islet Autoantibodies and Residual C-Peptide at the Clinical Onset of Type 1 Diabetes Mellitus and the Risk of Retinopathy 15 Years Later. Free full text available in HTML and PDF formats.
  190. Residual Beta Cell Function in Newly Diagnosed Type 1 Diabetes after Treatment with Atorvastatin: The Randomized DIATOR Trial. Free full text available in HTML and PDF formats.

    16 March 2011

  191. Trends in Type 1 diabetes incidence in the UK in 0- to 14-year-olds and in 15- to 34-year-olds, 1991-2008.
  192. Islet autoantibodies can discriminate maturity-onset diabetes of the young (MODY) from Type 1 diabetes.
  193. Combination therapy with a dipeptidyl peptidase-4 inhibitor and a proton pump inhibitor induces beta-cell neogenesis from adult human pancreatic duct cells implanted in immunodeficient mice.

    9 March 2011

  194. Automated Overnight Closed-Loop Glucose Control in Young Children with Type 1 Diabetes.
  195. The Effect of Insulin Feedback on Closed Loop Glucose Control.
  196. Accelerated progression from islet autoimmunity to diabetes is causing the escalating incidence of type 1 diabetes in young children.
  197. Insulin autoantibodies with high affinity to the bovine milk protein alpha casein.
  198. The Incidence of Type-1 Diabetes in NOD Mice Is Modulated by Restricted Flora Not Germ-Free Conditions. Free full text available in HTML and PDF formats.
  199. Increased prevalence of proliferative retinopathy in patients with type 1 diabetes who are deficient in glucose-6-phosphate dehydrogenase.

    2 March 2011

  200. Endothelial Dysfunction Is Related to Poor Glycemic Control in Adolescents with Type 1 Diabetes under 5 Years of Disease: Evidence of Metabolic Memory.
  201. Maternal food consumption during pregnancy and risk of advanced beta-cell autoimmunity in the offspring.
  202. Low vitamin d levels correlate with the proinflammatory state in type 1 diabetic subjects with and without microvascular complications.

    23 February 2011

  203. Alginate Macroencapsulation of Pig Islets Allows Correction of Streptozotocin-Induced Diabetes in Primates up to 6 Months Without Immunosuppression.
  204. Long-lasting remission of type 1 diabetes following treatment with topiramate for generalized seizures.
  205. A health economic analysis of clinical islet transplantation.
  206. Glucagon-Like Peptide-1 Receptor Agonist Treatment Prevents Glucocorticoid-Induced Glucose Intolerance and Islet-Cell Dysfunction in Humans.
  207. Pulse Pressure Predicts Incident Cardiovascular Disease but Not Diabetic Nephropathy in Patients With Type 1 Diabetes (The FinnDiane Study).
  208. Skin Intrinsic Fluorescence Correlates With Autonomic and Distal Symmetrical Polyneuropathy in Individuals With Type 1 Diabetes.
  209. Milk A1 and A2 peptides and diabetes.
  210. Xenotransplantation of Cells for Diabetes: Is There a Good Acceptance Rate Among Spanish Adolescents?

    16 February 2011

  211. Evidence That Nasal Insulin Induces Immune Tolerance to Insulin in Adults With Autoimmune Diabetes.
  212. Multinational study of subcutaneous model-predictive closed-loop control in type 1 diabetes mellitus: summary of the results.
  213. Stepwise or Linear Decrease in Penetrance of Type 1 Diabetes With Lower-Risk HLA Genotypes Over the Past 40 Years.
  214. Alterations of platelet biochemical and functional properties in newly diagnosed type 1 diabetes: a role in cardiovascular risk?
  215. Inhibition of Type 1 Diabetes Correlated to a Lactobacillus johnsonii N6.2-Mediated Th17 Bias.
  216. In vivo genetic engineering of murine pancreatic beta cells mediated by single-stranded adeno-associated viral vectors of serotypes 6, 8 and 9.

    9 February 2011

  217. Impaired Endothelial Function in Preadolescent Children With Type 1 Diabetes.
  218. Enterovirus infection and type 1 diabetes mellitus: systematic review and meta-analysis of observational molecular studies. See also Enterovirus "linked to diabetes."
  219. Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes.
  220. The reversal of diabetes in rat model using mouse insulin producing cells - A combination approach of tissue engineering and macroencapsulation.

    2 February 2011

  221. Glucagon Receptor Knockout Prevents Insulin-Deficient Type 1 Diabetes in Mice. See also Rodent of the Week: A different approach to treating Type 1 diabetes and Destroying Glucagon Receptors May Cure Diabetes.
  222. Accelerated Insulin Pharmacokinetics and Improved Postprandial Glycemic Control in Patients With Type 1 Diabetes After Coadministration of Prandial Insulins With Hyaluronidase. (See also Halozyme Therapeutics Endocrinology Product Pipeline for more information.)
  223. The Possible Protective Role of Glucagon-Like Peptide 1 on Endothelium During the Meal and Evidence for an "Endothelial Resistance" to Glucagon-Like Peptide 1 in Diabetes .
  224. Urine C-Peptide Creatinine Ratio Is a Noninvasive Alternative to the Mixed-Meal Tolerance Test in Children and Adults With Type 1 Diabetes.
  225. Of Mouse & Man: Frustrations and Excitements in Diabetes Research. (Requires Facebook account)

    26 January 2011

  226. Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes.
  227. Tests for Genetic Interactions in Type 1 Diabetes; Linkage and Stratification Analyses of 4,422 Affected Sib-Pairs.
  228. Coexistent Autoimmunity in Familial Type 1 Diabetes: Increased Susceptibility in Sib-Pairs?

    19 January 2011

  229. Researchers find the enzyme at the heart of retinopathy caused by type 1 or type 2 diabetes. See also Increased Expression and Activity of 12-Lipoxygenase in Oxygen-Induced Ischemic Retinopathy and Proliferative Diabetic Retinopathy.
  230. Closed-Loop Insulin Delivery During Pregnancy Complicated by Type 1 Diabetes.
  231. Proinsulin/C-peptide ratio, glucagon and remission in new-onset Type 1 diabetes mellitus in young adults.
  232. Effect of Automated Bio-Behavioral Feedback on the Control of Type 1 Diabetes.
  233. Anti-thymoglobulin (ATG) treatment does not reverse type 1 diabetes in the acute virally induced rat insulin promoter-lymphocytic choriomeningitis virus (RIP-LCMV) model.

    12 January 2011

  234. On the Occurrence of the Diabetes-Associated Antigen GAD 65 in Human Sera.
  235. A novel technique for the in vivo imaging of autoimmune diabetes development in the pancreas by two-photon microscopy. Free full text available in HTML and PDF formats.
  236. Pregnancy-induced increase in circulating IGF-I is associated with progression of diabetic retinopathy in women with type 1 diabetes.
  237. Genetics of Type 1 Diabetes.
  238. Impaired insulin stimulation of muscular ATP production in patients with type 1 diabetes.
  239. Correction of Hyperglycemia in Type 1 Diabetic Models by Transplantation of Encapsulated Insulin-producing Cells Derived from Mouse Embryo Progenitor.

    5 January 2011

  240. HbA(1c) levels in schoolchildren with type 1 diabetes are seasonally variable and dependent on weather conditions.
  241. Low-dose aspirin for primary prevention of cardiovascular events in patients with diabetes: a meta-analysis.
  242. Prospective comparison of two methods of screening for diabetic retinopathy by nonmydriatic fundus camera. Free full text available in HTML and PDF formats.
  243. Effects of Serving High-Sugar Cereals on Children's Breakfast-Eating Behavior.

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