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Research News From 2018

    21 March 2018

  1. [New!] Unannounced Meals in the Artificial Pancreas: Detection Using Continuous Glucose Monitoring. Free full text available in HTML and PDF formats.
  2. [New!] Peptide Immunotherapy for Type 1 Diabetes-Clinical Advances. Free full text available in HTML and PDF formats.
  3. [New!] Superior Glycemic Control with a Glucose-Responsive Insulin Analog: Hepatic and Nonhepatic Impacts.
  4. [New!] Viral insulin-like peptides activate human insulin and IGF-1 receptor signaling: A paradigm shift for host–microbe interactions. See also Insulin Goes Viral?

    14 March 2018

  5. A phase 3 multicenter, open-label, prospective study designed to evaluate the effectiveness and ease of use of nasal glucagon in the treatment of moderate and severe hypoglycemia in children and adolescents with type 1 diabetes in the home or school setting.
  6. Paracrine Interactions within the Pancreatic Islet Determine the Glycemic Set Point. See also Researchers Confirm Entire Islet Organ is the Master Regulator of Blood Glucose Levels.
  7. α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes.
  8. Adrenaline and cortisol levels are lower during nighttime than daytime hypoglycaemia in children with type 1 diabetes.

    7 March 2018

  9. Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables. See also Diabetes is actually five separate diseases, research suggests.
  10. A prospective study evaluating the use of nasal glucagon for the treatment of moderate to severe hypoglycemia in adults with type 1 diabetes in a real-world setting.
  11. Seasonal Variation in Month of Diagnosis of Polish Children with Type 1 Diabetes - A Multicenter Study.
  12. Preventing Nocturnal Hypoglycemia: Single- vs Dual-Hormone Artificial Pancreas System.
  13. Safety and Efficacy of Epigenetically Converted Human Fibroblasts Into Insulin-Secreting Cells: A Preclinical Study.

    28 February 2018

  14. Clustering of microvascular complications in Type 1 diabetes mellitus.
  15. Human Subcutaneous Tissue Response to Glucose Sensors: Macrophages Accumulation Impact on Sensor Accuracy.

    21 February 2018

  16. A plateau in new onset type 1 diabetes: Incidence of pediatric diabetes in the United States Military Health System.
  17. Methyldopa blocks MHC class II binding to disease-specific antigens in autoimmune diabetes. Free full text available in PDF format. See also Researchers find existing drug effective at preventing onset of type 1 diabetes.
  18. Type 1 diabetes susceptibility alleles are associated with distinct alterations in the gut microbiota. See also Researchers discover link between gut and type 1 diabetes.
  19. Optimizing Hybrid Closed-Loop Therapy in Adolescents and Emerging Adults Using the MiniMed 670G System.

    14 February 2018

  20. Impact of erroneous meal insulin bolus with dual-hormone artificial pancreas using a simplified bolus strategy - A randomized controlled trial.
  21. Impact of C-Peptide Status on the Response of Glucagon and Endogenous Glucose Production to Induced Hypoglycaemia in T1D.
  22. Beta Cell Function after Intensive Subcutaneous Insulin Therapy or Intravenous Insulin Infusion at Onset of T1D in Children without ketoacidosis.
  23. A type 1 diabetes genetic risk score can discriminate monogenic autoimmunity with diabetes from early-onset clustering of polygenic autoimmunity with diabetes.
  24. Administration of vitamin D and high dose of omega 3 to sustain remission of type 1 diabetes.
  25. Coxsackievirus B1 infections are associated with the initiation of insulin-driven autoimmunity that progresses to type 1 diabetes..
  26. Virus-like infection induces human β cell dedifferentiation.

    7 February 2018

  27. Overnight Glucose Control with Dual- and Single-Hormone Artificial Pancreas in Type 1 Diabetes with Hypoglycemia Unawareness: A Randomized Controlled Trial.
  28. Hypoglycemia unawareness in type 1 diabetes suppresses brain responses to hypoglycemia.
  29. A Prospective Multicenter Evaluation of the Accuracy of a Novel Implanted Continuous Glucose Sensor: PRECISE II.

    31 January 2018

  30. Excess Mortality in Patients With Type 1 Diabetes Without Albuminuria—Separating the Contribution of Early and Late Risks.
  31. Type 1 Diabetes in Parents and Risk of Attention Deficit Hyperactivity Disorder in Offspring: A Population-Based Study in Sweden.
  32. Soft, smart contact lenses with integrations of wireless circuits, glucose sensors, and displays.

    24 January 2018

  33. Decreased α-cell mass and early structural alterations of the exocrine pancreas in patients with type 1 diabetes: An analysis based on the nPOD repository. Free full text available in HTML and PDF formats.
  34. Dual-hormone artificial pancreas: benefits and limitations compared with single-hormone systems.
  35. Low-grade Inflammatory Marker Profile May Help to Differentiate Patients With LADA, Classic Adult-Onset Type 1 and Type 2 Diabetes.

    17 January 2018

  36. Early Infant Diet and Islet Autoimmunity in the TEDDY Study.
  37. Incidence of type 1 diabetes in China, 2010-13: population based study. See also Type 1 Diabetes on the Rise in China, Most New Cases in Adults.
  38. Incidence of childhood onset type 1 diabetes in Western Australia from 1985 to 2016: Evidence for a plateau.
  39. Basal Insulin Peglispro Increases Lipid Oxidation, Metabolic Flexibility, Thermogenesis And Ketone Bodies Compared To Insulin Glargine In Subjects With Type 1 Diabetes Mellitus.
  40. Efficacy and safety of fast-acting insulin aspart in comparison with insulin aspart in type 1 diabetes (onset 1): a 52-week, randomized, treat-to-target, phase 3 trial.

    10 January 2018

  41. Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes: The TRIGR Randomized Clinical Trial. See also Modifying baby formula doesn't prevent type 1 diabetes in children.
  42. Infant Feeding in Relation to the Risk of Advanced Islet Autoimmunity and Type 1 Diabetes in Children With Increased Genetic Susceptibility: A Cohort Study.
  43. Endogenous Reprogramming of Alpha Cells into Beta Cells, Induced by Viral Gene Therapy, Reverses Autoimmune Diabetes.
  44. Reversible retinal vessel closure from VEGF-induced leukocyte plugging.
  45. Method may reverse vision loss from diabetes.
  46. Incidence of type 1 diabetes in China, 2010-13: population based study. Free full text available in HTML and PDF formats.

    3 January 2018

  47. Distinct fecal and oral microbiota composition in human type 1 diabetes, an observational study. Free full text available in HTML and PDF formats.
  48. Effect of a Glucagon Receptor Antibody (REMD-477) in Type 1 Diabetes: A Randomized Controlled Trial.
  49. Transplantation of Macro-encapsulated Human Islets within the Bioartificial Pancreas β Air to Patients with Type 1 Diabetes Mellitus.
  50. Designing a retrievable and scalable cell encapsulation device for potential treatment of type 1 diabetes. See also Spider web inspired implantable "string" could control diabetes.
  51. Incidence and prevalence trends of youth-onset type 2 diabetes in a cohort of Canadian youth: 2002-2013.

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Last Updated: Wednesday March 21, 2018 17:27:29
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