In what month were you or your child diagnosed?
Total votes: 1011
In what month were you or your child diagnosed?Poll dates: March 5 - 12, 2006
Total Votes: 1,011
Researchers from around the world have looked at diagnosis data to determine if there is seasonal variability. Some of this research dates to the early 1990s. The published data offers conflicting results, some possible clues, but no clear evidence.
One study conducted in Finland showed that low levels of vitamin D3 correlated to an increased risk of developing type 1 diabetes. Since we get much of our vitamin D from exposure to sunlight, some could argue that there will be higher rates of diagnosis in the winter and in higher latitudes.
Another study looked at children from the UK and Europe from 1989 on and found no evidence of seasonality of diagnosis in Europe and some peaks in Scotland, Yorkshire and Leicester.
Yet another study found significant seasonal patterns in children diagnosed in Finland and Sardinia, the two areas of the world with the highest rate of type 1 diabetes.
The following graphs provide two different views of the data. Click to view a larger resolution image. You may also download the Excel spreadsheet with these graphs included.
For more information on research into the seasonality of diagnosis of type 1 diabetes, see:
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- Low levels of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 in patients with newly diagnosed type 1 diabetes
(Horm Metab Res. 2005 Nov;37(11):680-3).
- Seasonality in clinical onset of Type 1 diabetes in Belgian patients above the age of 10 is restricted to HLA-DQ2/DQ8-negative males, which explains the male to female excess in incidence
(Diabetologia. 2004 Apr;47(4):614-21). Free full text available in HTML and PDF formats.
- Seasonality of birth in patients with childhood Type I diabetes in 19 European regions
(Diabetologia. 2001 Oct;44 Suppl 3:B67-74).
- Comparison of the seasonal pattern in the clinical onset of IDDM in Finland and Sardinia
(Diabetes Care. 1998 Jul;21(7):1101-9). Free full text available in PDF format.
- Long-term patterns in seasonality of insulin-dependent diabetes mellitus diagnosis in Austrian children
(J Clin Epidemiol. 1997 Feb;50(2):159-65).
- Raised IgG and IgM in "epidemic" IDDM suggest that infections are responsible for the seasonality of type I diabetes
(Diabetes Res. 1991 Jan;16(1):11-7).
- Seasonality of type 1 (insulin-dependent) diabetes mellitus: values of C-peptide, insulin antibodies and haemoglobin A1c show evidence of a more rapid loss of insulin secretion in epidemic patients.
(Diabetologia. 1989 Feb;32(2):84-91).
Last Updated: Sunday March 12, 2006 12:47:42
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