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November 26, 2008
- Differences in prevalence of antibodies to GAD and IA-2 and their titers at diagnosis in children with slowly and rapidly progressive forms of type 1 diabetes.
- Endocrine autoimmunity in families with type 1 diabetes: frequent appearance of thyroid autoimmunity during late childhood and adolescence.
- Impaired Hyperglycemia-Induced Delay in Gastric Emptying in Patients With Type 1 Diabetes Deficient for Islet Amyloid Polypeptide.
- Iodine and tri-iodo-thyronine reduce the incidence of type 1 diabetes mellitus in the autoimmune prone BB rats.
November 19, 2008
- Fasting plasma C-peptide and micro- and macrovascular complications in a large clinic-based cohort of type 1 diabetic people.
- Exenatide Sensitizes Insulin-mediated Whole-body Glucose Disposal and Promotes Uptake of Exogenous Glucose by the Liver.
- Influence of cardiovascular autonomic neuropathy on atherogenesis and heart function in patients with Type 1 diabetes.
- Recovery of endogenous beta cell function in non-human primates following chemical diabetes induction and islet transplantation.
- Tyrosine kinase inhibitors reverse type 1 diabetes in nonobese diabetic mice. See also Two cancer drugs prevent, reverse type 1 diabetes, UCSF study shows.
- Mitomycin C-treated dendritic cells inactivate autoreactive T cells: Toward the development of a tolerogenic vaccine in autoimmune diseases. Free full text available in PDF format.
- Egg Consumption and Risk of Type 2 Diabetes in Men and Women.
November 12, 2008
- Completely Novel Action Of Insulin Unveiled. The scientific paper is CaMKII-Mediated Phosphorylation of the Myosin Motor Myo1c Is Required for Insulin-Stimulated GLUT4 Translocation in Adipocytes.
- A 10-year (1996-2005) prospective study of the incidence of Type 1 diabetes in Moscow in the age group 0-14 years.
- Vitamin D and diabetic nephropathy.
- Evaluation of adiponectin level in children and adolescents with diabetes type 1.
- Distinct autoantibodies against exocrine pancreatic antigens in European patients with type 1 diabetes mellitus and non-alcoholic chronic pancreatitis.
- The influence of diabetes mellitus type 1 and 2 on the thickness, shape, and equivalent refractive index of the human crystalline lens.
November 5, 2008
- Effects of oral consumption of the green tea polyphenol EGCG in a murine model for human Sjogren’s syndrome, an autoimmune disease. See also Green tea may delay onset of type 1 diabetes.
- Childhood type 1 diabetes in Iceland; Evaluation of quality of treatment.
- Pitfalls in the measurement of the nocturnal blood pressure dip in adolescents with type 1 diabetes.
- Treatment of Experimental Periodontal Disease by Photodynamic Therapy in Rats With Diabetes.
October 29, 2008
- Glucose and C-Peptide Changes in the Perionset Period of Type 1 Diabetes in the Diabetes Prevention Trial�Type 1.
- Role of coxsackievirus B4 in the pathogenesis of type 1 diabetes.
- The growing incidence of type 1 diabetes in children: The 17-year French experience in Aquitaine.
- Lessons learned from studies of the natural history of diabetic nephropathy in young type 1 diabetic patients.
- Oxidative stress as a common mediator for apoptosis induced-cardiac damage in diabetic rats. Free full text available in HTML and PDF formats.
- Experimental microencapsulation of porcine and rat pancreatic islet cells with air-driven droplet generator and alginate.
October 22, 2008
- Kinetics of Insulin Secretion from MIN6 Pseudoislets after Encapsulation in a Prototype Device of a Bioartificial Pancreas.
- Relationship between beta-cell mass and diabetes onset.
- A new model defines the minimal set of polymorphism in HLA-DQ and -DR that determines susceptibility and resistance to autoimmune diabetes. Free full text available in PDF format.
- Orally administered microencapsulated lysozyme downregulates serum AGE and reduces the severity of early-stage diabetic nephropathy.
- Serum endogenous secretory RAGE level is an independent risk factor for the progression of carotid atherosclerosis in type 1 diabetes.
October 15, 2008
- GAD Treatment and Insulin Secretion in Recent-Onset Type 1 Diabetes. Free full text available in HTML and PDF formats. Immunotherapy on Trial for New-Onset Type 1 Diabetes (PDF) is an accompanying editorial by Denise L. Faustman, M.D., Ph.D. See also Type 1 Diabetes Vaccine May Preserve Some Insulin Production (includes audio clip), New Vaccine May Help Type 1 Diabetics in Future; Early study finds it appears to sustain insulin production in the newly diagnosed and Diamyd� Study Published In Prestigious New England Journal Of Medicine.
- High prevalence of vitamin D deficiency in type 1 diabetes mellitus and healthy children.
- Curative and beta cell regenerative effects of alpha-1-antitrypsin treatment in autoimmune diabetic NOD mice. See also AAT Protein Restores Blood Glucose in Type 1 Diabetes Model.
- Glucagon like peptide-2 reduces intestinal permeability but does not modify the onset of type 1 diabetes in the non obese diabetic mouse. Free full text available in PDF format.
- Food consumption and the risk of type 1 diabetes in children and youth: a population-based, case-control study in Prince Edward Island, Canada.
- Low-protein diet for diabetic nephropathy: a meta-analysis of randomized controlled trials.
- Researchers Finish Work on Needle-free Glucose Tester.
October 8, 2008
- Can glycaemic variability, as calculated from blood glucose self-monitoring, predict the development of complications in type 1 diabetes over a decade?
- Participant and parent experiences in the oral insulin study of the Diabetes Prevention Trial for Type 1 Diabetes.
- The TrialNet Natural History Study of the Development of Type 1 Diabetes: objectives, design, and initial results.
- JDRF randomized clinical trial to assess the efficacy of real-time continuous glucose monitoring in the management of type 1 diabetes: research design and methods.
- Combination Therapy with Glucagon-Like Peptide-1 and Gastrin Restores Normoglycemia in Diabetic NOD Mice.
- Researchers See Neurological Cause of Diabetes in Pancreatic Nociceptors. Also available in PDF format.
- Weight gain in early life predicts risk of islet autoimmunity in children with a first degree relative with type 1 diabetes.
- Rate of {beta}-cell Destruction in Type 1 Diabetes Influences the Development of Diabetic Retinopathy: Protective Effect of Residual {beta}-cell Function for More Than 10 Years. Free full text available in PDF format.
- Effect of candesartan on prevention (DIRECT-Prevent 1) and progression (DIRECT-Protect 1) of retinopathy in type 1 diabetes: randomised, placebo-controlled trials.
- Quantitative Assessment of Early Diabetic Retinopathy Using Fractal Analysis.
- Predictive value of color Doppler imaging in an evaluation of retrobulbar blood flow perturbation in young type-1 diabetic patients with regard to dyslipidemia.
- Role of Humphrey-Matrix Frequency Doubling Technology Perimetry threshold strategy in the Early Diagnosis of Retinopathy in Type 1 Diabetes.
- Elevated plasma adiponectin and decreased plasma homocysteine and asymmetric dimethylarginine in children with type 1 diabetes.
- Follow up analysis of genome-wide association data identifies novel loci for type 1 diabetes.
- Insulin gene mutations as cause of diabetes in children negative for five type 1 diabetes autoantibodies.
- Safety and efficacy of inhaled human insulin (Exubera(R)) during discontinuation and readministration of therapy in adults with type 1 diabetes: A 3-year randomized controlled trial.
- Assessment of long-term immunological and pulmonary safety of inhaled human insulin with up to 24 months of continuous therapy.
- Effects of inhaled human insulin on airway lining fluid composition in adults with diabetes.
- NIH Launches New Web Site for Parents on Medical Research Studies for Children. See also the Children & Clinical Studies web site.
October 1, 2008
- Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial.
- Innate immunity and intestinal microbiota in the development of Type 1 diabetes.
- The “Perfect Storm” for Type 1 Diabetes: The Complex Interplay Between Intestinal Microbiota, Gut Permeability, and Mucosal Immunity.
- Combination therapy with glucagon-like peptide-1 and gastrin induces beta-cell neogenesis from pancreatic duct cells in human islets transplanted in immunodeficient diabetic mice.
- Hs-CRP is associated with weight, BMI, and female sex but not with endothelial function in children with type 1 diabetes.
- Glycaemic variability and inflammation in subjects with metabolic syndrome.
- Taurine rescues vascular endothelial dysfunction in streptozocin-induced diabetic rats: Correlated with downregulation of LOX-1 and ICAM-1 expression on aortas.
- Prolonged Insulin Independence After Islet Allotransplants in Recipients with Type 1 Diabetes.
- Prolonged antidiabetic effect of zinc-crystallized insulin loaded glycol chitosan nanoparticles in type 1 diabetic rats.
- Prevalence of type 1 diabetes mellitus in Saudi Arabian children and adolescents.
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