Need Help

Submit your question to our team of health care professionals.

Current Question

See what's on the mind of the community right now.

Meet the Team

Learn more about our world-renowned team.

CWD Answers Archives

Review the entire archive according to the date it was posted.

July 30, 2013

Hypoglycemia, Insulin Analogs

Question from Encinitas, California, USA:

While sleeping, I have been experiencing seizures due to low sugars. While I am awake, I feel lows coming on and drink juice or eat a cookie or do whatever needs to be done. I have had 24 seizures over six weeks, all while sleeping. I have needed frosting to be given to me and also a glucagon shot. At other times, I was able to drink juice with assistance. These episodes only happen at nighttime and I have since then gotten a Dexcom CGMS. I have made quite a few changes to my basal rate and my correction rates on my pump. This all started happening when my health insurance changed me from Apidra to Humalog. I was told that there is not much of a difference. It has been seven weeks now of pure fear of going to sleep. The Dexcom is now waking me up and I have not had a seizure since I got the Dexcom, but have any of you heard of a person being super sensitive to Humalog? I have not had any weight loss and have not changed my diet, and I am definitely less active because I am awakened at all hours of the night with the Dexcom beeping at me saying get up and get some juice.


From: DTeam Staff

I am sorry for your struggles. It sounds very difficult to try and do all this adjusting and have a fear of going to sleep. I am glad the glucose sensor has helped you with this problem.

I am not aware that there should be a big difference between Apidra and Humalog. However, it is what it is and adjustments still have to be made. My feeling is that I can make either Apidra or Humalog work. It is just one more variable you have to adjust for.

Be sure to continue to work with your doctor. It has been shown that aggressive avoidance of lows for several weeks may allow you to regain some of your hypoglycemic symptoms. Because your problems are rather severe in nature, be sure you are working closely with your physician to eliminate the low sugars.