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December 26, 2002

Honeymoon

Question from New Jersey, USA:

Besides other factors such as the tightness of the control of blood glucose, is there any information to support the concept that the duration of the honeymoon period in type 1 diabetes is generally longer in kids than in adolescents, young adults, or older adults?

Answer:

You got it backwards. The older you are and the slower your onset of pancreatic beta cells demise, the more likely to have a honeymoon and the longer it lasts. So, the least likely honeymooners are little kids. Most likely, slow onset or Late-onset Autoimmune Diabetes of Adulthood (LADA). Late teens and young adults more likely to honeymoon then preteens and teens, etc.

There are some data, but not definitely proven, that tight control of glucose removes “glucotoxicity” and allows more beta cell function recovery. Many of us diabetologists try to get glucose control as close to normal as soon as possible to see if this promotes a stable/honeymoon phase, but the science behind all of this is sketchy.

SB
Additional comments from Dr. Marco Songini:

As far as I know, the opposite is true.

MS