Justin Delgado is husband to Kacie Doyle-Delgado, diagnosed at age 11. After more than a decade together, he considers himself to be an expert carb counter and Dexcom inserter. He graduated with his Master of Science in Finance from the University of Utah in 2013 and has been working in commercial banking since then. He attended his first Friends for Life conference in 2015 and is looking forward to volunteering with the teens.
June 30, 2007
Question from India:
Can endothelial dysfunction cause decreased extravascular movement of insulin? In the case of delayed extravascular movement of insulin, will intact insulin persist in the blood for a period longer than its half life?
It is unlikely that endothelial dysfunction is caused by impaired movement of insulin. First, insulin is too small to be severely restricted across the endothelial barrier. This is not a limiting step. It is usually absolute insulin deficiency or insulin resistance of the tissues in the extracellular space that make the biggest difference.