Justin Delgado is husband to Kacie Doyle-Delgado, diagnosed at age 11. After more than a decade together, he considers himself to be an expert carb counter and Dexcom inserter. He graduated with his Master of Science in Finance from the University of Utah in 2013 and has been working in commercial banking since then. He attended his first Friends for Life conference in 2015 and is looking forward to volunteering with the teens.
June 9, 1999
Hyperglycemia and DKA
Question from North Carolina, USA:
Can one develop resistance to long acting insulin (NPH)? My morning blood sugars are high. During the day when I take Humalog, they are more stable. Increasing the night time shot does not seem to help.
Not at all. I think what you observe (called the dawn phenomenon) is quite common due to relatively low doses of insulin over the first part of the nighttime secondary to the short half-life of the supper dose of lispro insulin [Humalog� brand].
It sounds as you should first check whether:
The NPH is injected at a sufficient dose and at bedtime;
The 3:00 A.M. blood sugar is okay, to be sure that you avoid the Somogyi Effect
and then adjust your regimen accordingly, under the supervision of your diabetes team.