Question from Miami, Florida, USA:
My nine year old son uses an insulin pump, and his blood sugars are pretty predictable and good during the day, but they rise significantly (250-450 mg/dl [13.9-25 mmol/L]) between 12:00 midnight and 2:00 am, even when he goes to bed with a blood glucose of 100-150 mg/dl [5.6-8.3 mmol/L]. I am baffled by high sugars during this time because insulin requirements are supposed to be lower than normal.
My son's basal rate is set at 0.5 units per hour for most of the day, at 9:00 pm, I raise it to 0.8 units per hour, and then from 11:00 pm-12:00 midnight, it is 1.3 units per hour to try to deal with the high sugars almost certainly to come. Even this doesn't always help, and needless to say, I must test him every night just in case he doesn't go high and goes low from the extra insulin. I have never heard of anyone having this problem before, nor of a possible cause for this increase in blood glucose. Can you help?