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August 23, 2001

Genetics and Heredity

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Question from England:

I have celiac syndrome, my husband has type 2 diabetes, and we have three sons with language/development delays, behavior problems, etc. Is there any possibility of fragile X in my sons from being linked to the celiac disease or diabetes?

Answer:

From: DTeam Staff

Fragile X syndrome is due to an abnormal expansion of the FMR1 Gene on the X chromosome and a consequent deficiency in the protein FMRP. There is no recorded evidence of a link to celiac syndrome which is an autoimmune disorder or to any form of type 2 diabetes.

DOB