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March 31, 2010

Insulin

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Question from India:

Is it possible that extra insulin can interfere in filtration from micro-vessels and from liver, kidney, etc. and cause some problem in view of that it is a big molecule and exogenous insulin can be bit odd for body’s normal handling? Excess and continual exposure of insulin may also cause its decreased use due to insulin resistance and decreased degradation so circulating insulin can be more.

Answer:

From: DTeam Staff

The rate limiting step in insulin absorption is absorption from a subcutaneous site. It is rather efficiently absorbed without much difficulty. Previous studies have shown that insulin resistance is not related to absorption at the injection site.

JTL