Justin Delgado is husband to Kacie Doyle-Delgado, diagnosed at age 11. After more than a decade together, he considers himself to be an expert carb counter and Dexcom inserter. He graduated with his Master of Science in Finance from the University of Utah in 2013 and has been working in commercial banking since then. He attended his first Friends for Life conference in 2015 and is looking forward to volunteering with the teens.
August 11, 2006
Pills for Diabetes
Question from Connecticut, USA:
I am a pharmacist. I was given a prescription for Actos for a seven year old obese child. The doctor said the child has taken it before, but I cannot find any information about its safe use by children. Can you provide me with information?
Pioglitazone (Actos) is not FDA-approved for use in pediatric patients. That said, a licensed physician can prescribe whatever legal substance, off label.
There is a small body of literature on the use of pioglitazone and other thiazolidinediones in pediatric patients with obesity and fatty-liver disease; pharmacokinetic studies; and others. As you know, just because a drug is “not FDA-approved” does not mean that is “disapproved” by the FDA.
Pharmaceutical companies have little interest in doing the clinical trials needed in children for a drug that likely will not have much of a pediatric market. Unfortunately, we are seeing more obesity and type 2 diabetes in children now.
So, with bias, I say: fill the prescription.