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December 31, 2006

Hyperglycemia and DKA, Other

Question from India:

Is the quantity of urine passed in 24 hours related more or less to the loss of sugar in urine and consequent variations in blood glucose levels? Will a type 2 diabetic with persistent hyperglycemia have a blood sugar dependent upon the amount of urine he passes?


You are correct when you suggest that people with high blood sugar make more urine. The high glucose causes an osmotic diuresis. In effect, the high glucose in the urine pulls water with it from the kidneys. Only late in kidney failure do you have a marked decrease in urine production. Overall, the amount of urine does not reflect kidney function.