Lg Cwd
icon-nav-help
Need Help

Submit your question to our team of health care professionals.

icon-nav-current-questions
Current Question

See what's on the mind of the community right now.

icon-conf-speakers-at-a-glance
Meet the Team

Learn more about our world-renowned team.

icon-nav-archives
DTeam Archives

Review the entire archive according to the date it was posted.

icon-question-mark
December 4, 2003

Hyperglycemia and DKA, Insulin Pumps

Question from Barrie, Ontario, Canada:

My 15 year old daughter has had type 1 diabetes for two years now. She went on an insulin pump one year ago, and after the learning curve, a bit of a struggle with the honeymoon period, and a bout with DKA, her BG levels have been very good and had two back to back A1cs of 6.6. For the last week or so, her levels have stayed continuously high (15-20 mmol/l [270-360 mg/dl]) and ketone readings between 0.2 and 1.0. We have increased her basal rate, bolused the extra 10-15% on top of the correction bolus as recommended depending on the ketone level, but her readings seem to be staying in the 15-20 range. She has not felt good this past week, but I can't tell if it's the high readings making her feel dizzy, or an underlying illness that is causing these high readings. We have visited both our GP and her specialist and they just tell us to give her more insulin. We are always a little wary in giving her large doses as we are worried that she will drop too low. Is it possible that a growth spurt at this age may create a permanent higher demand for insulin? She is currently taking 1.8 units per hour basal on the pump, and boluses 1 unit for 12 grams of carbs, and correction bolus being used is 1 unit to drop the blood glucose 2 mm/l. Her TDD of insulin has been about 60, but lately it has climbed to over 75 and still the high readings.

Answer:

I wonder if the insulin pump is malfunctioning since nondelivery of insulin would obviously cause high sugars and ketones. I would certainly also look for underlying infection or other cause of blocking insulin action as well. Sometimes teenagers purposefully omit taking their insulin and this could be difficult to determine. This often happens if they are overeating and then use insulin omission as a way of not gaining weight since the hyperglycemia causes glucose urine loss – and uncontrolled diabetes. This is what we call diabulimia – a form of bulimic behavior that is very dangerous – especially if omitted insulin occurs to the point of ketonuria or ketoacidosis. You should go back to your diabetes team and problem solve in more detail. She may need to be in the hospital for more direct observation to see if there is some underlying cause.

SB