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December 2, 2003

Tight Control

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Question from Anchorage, Alaska, USA:

My son is 7 years old and has had type 1 diabetes for about 4 years. We have had an ongoing problems of mid morning high blood sugars. We monitor him closely at night (to be sure he is not “bottoming out”) and he usually wakes up within range of 100-150 mg/dl [5.5-8.3 mmol/l]. However, when he gets his mid-morning check, approximately 2.5 hours after his insulin injection, he will have very high blood sugars, ranging from 300-450 mg/dl [16.6-25 mmol/l]. When he gets checked for lunch, about one hour later, he will have dropped drastically, and usually ends up between 60-130 mg/dl [3.3-7.2 mmol/l] at lunch. We have found that if we give enough fast acting insulin, in order to “cover” the mid morning highs, it is almost impossible to feed him enough over the next hour to get him to lunch without a major low.

We have tried several combinations of insulin, (Humalog/NPH, Humalog/Lantus, regular/NPH, and regular/Humalog/Lantus) and we continue to get the same results. Do you know what might be causing this, and do you have any suggestions on how to solve this problem? He gets about 60 grams of carbs for breakfast every morning.

Answer:

From: DTeam Staff

If one looks in the literature, your situation isn’t unique. It is very hard to give insulin that yields a good breakfast followed by a good lunch with a good in between number. The insulin just isn’t absorbed like you would hope it would be. The peak is hard to avoid, indeed, maybe impossible without causing the hypos. I tend to ignore it, especially if the A1c is where I want it to be. The obvious answer is fewer carbs, but I wouldn’t do it.

LD