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January 27, 2002

Insulin Analogs

Question from Lansing, Michigan, USA:

My two boys, ages 9 and 11, both have type 1 diabetes, and the 11 year old does not have good control with Humalog and NPH. I am considering asking his doctor for a change to Humalog with Lantus, but I would like to know what type of experiences children have had who use Lantus.


You may want to go to some Chat Rooms for specific individual experience with Lantus (insulin glargine) in children and adolescents. We and several other pediatric diabetology groups have been using Lantus quite successfully for the past seven months in children and seem to see fewer nocturnal hypoglycemia episodes, and better pre-breakfast insulin coverage. However, you need to individualize treatment with Lantus and may need lunchtime NPH or afternoon Humalog coverage if the Lantus lasts only 18 hours rather than 24 hours. This is rather common with many of the kids we are treating.

You should go back to your own diabetes team and discuss this of course.