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October 22, 2001

Insulin Analogs

Question from Merritt Island, Florida, USA:

My two year old has newly diagnosed type�1 diabetes. Do you have any information on the insulin activity of insulin glargine (Lantus) after the initial 24 hours?


There is very little information about Lantus (insulin glargine) in very young children. Clinically, it may not last as long in young children as it does in adults, i.e., there may be some waning effect so that you need two doses of Lantus or some NPH at lunchtime in addition to Humalog. You should discuss this with your child’s diabetes team and do lots of blood glucose monitoring since all doses should be individualized.