Question from Virginia, USA:
My son was diagnosed about eight months ago. He was changed to NovoLog before meals about two months ago. Oddly, he ran high (300s mg/dl [16.7 to 16.3 mmol/L]) two to two and half hours after NovoLog and a meal, despite adjusting ratios between 20:1 down to 10:1. However, like clockwork, at three and a half hours after NovoLog, every time, his blood sugar dropped dramatically into the 40 to 60 mg/dl [2.2 to 3.8 mmol/L] range. It was as if he were having a delayed response to the NovoLog. This went on for three weeks until I asked for Humalog, which he then responded to as we would expect, blood sugars in mid 100s mg/dl [around 8.0 mmol/L] two hours after a meal. I had the impression that NovoLog and Humalog were very similar. Do you think we may have just gotten a bad bottle of NovoLog? Or, do you think there is some physiological reason for this reaction?