Research News From September 2, 2007
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- HLA-DPB1*0402 protects against type 1A diabetes autoimmunity in the highest risk DR3-DQB1*0201/DR4-DQB1*0302 DAISY population.
- Expression of cholera toxin B�proinsulin fusion protein in lettuce and tobacco chloroplasts � oral administration protects against development of insulitis in non-obese diabetic mice. See also Insulin Grown in Plants Relieves Diabetes in Mice; UCF Study Holds Promise for Humans and Local Professor Begins Human Trials For Diabetes Cure.
- Bone Marrow Is a Preferential Homing Site for Autoreactive T-Cells in Type 1 Diabetes.
- Vessel wall stiffness in Type 1 diabetes, and the central hemodynamic effects of acute hypoglycemia.
- Plasma endothelin response to acute hypoglycaemia in adults with Type 1 diabetes.
- Overexpression of the autoantigen IA-2 puts beta cells into a pre-apoptotic state: autoantigen-induced, but non-autoimmune-mediated, tissue destruction.
