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Research News From June 24, 2015

Alterations in Intestinal Microbiota Correlate with Susceptibility to Type 1 Diabetes. Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery. See also Smart insulin patch could replace painful injections for diabetes. Insulin Delivery into the Peripheral Circulation: a Key Contributor to Hypoglycemia in Type 1 Diabetes. New Insulin Glargine 300 Units/mL Versus Glargine 100 Units/mL in People With Type 1 Diabetes: A Randomized, Phase 3a, Open-Label Clinical Trial (EDITION 4). Long-Term Control of Diabetes in Immunosuppressed Nonhuman Primates (NHP) by the Transplantation of Adult Porcine Islets. Empagliflozin as adjunct to insulin in patients with type 1 diabetes: a […]

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Research News From June 17, 2015

Efficacy of dual-hormone artificial pancreas to alleviate the carbohydrate-counting burden of type 1 diabetes: A randomized crossover trial. Outpatient overnight glucose control with dual-hormone artificial pancreas, single-hormone artificial pancreas, or conventional insulin pump therapy in children and adolescents with type 1 diabetes: an open-label, randomised controlled trial. See also Which artificial pancreas system is the best for children with type 1 diabetes? Artificial Pancreas (AP) Technology Take the Stage at the 75th Annual American Diabetes Association (ADA) Conference. Hope Ahead? Varying Approaches Progress Artificial Pancreas. Bionic pancreas effective therapy in preadolescent summer camp setting. Non-HLA gene effects on the disease […]

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Research News From June 10, 2015

Sugar intake is associated with progression from islet autoimmunity to type 1 diabetes: the Diabetes Autoimmunity Study in the Young. Predictive Low-Glucose Insulin Suspension Reduces Duration of Nocturnal Hypoglycemia in Children Without Increasing Ketosis. Free full text available in PDF format. Day and Night Closed-Loop Control Using the Integrated Medtronic Hybrid Closed-Loop System in Type 1 Diabetes at Diabetes Camp. Free full text available in PDF format. Sotagliflozin, a Dual SGLT1 and SGLT2 Inhibitor, as Adjunct Therapy to Insulin in Type 1 Diabetes. Free full text available in PDF format. Glucagon – the new ‘insulin’ in the pathophysiology of diabetes.

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Research News From June 3, 2015

Fabrication of three-dimensional bioplotted hydrogel scaffolds for islets of Langerhans transplantation. See also 3D-printed scaffolds may make for improved diabetes treatment. Stable Incretin Mimetics Counter Rapid Deterioration of Bone Quality in Type 1 Diabetes Mellitus. Gestational and Early Infancy Exposure to Margarine Fortified with Vitamin D through a National Danish Programme and the Risk of Type 1 Diabetes: The D-Tect Study. Free full text available in HTML and PDF formats. Vitamin D levels at birth and risk of type 1 diabetes in childhood: a case-control study.

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Research News From May 27, 2015

Association between hypoglycaemia and impaired hypoglycaemia awareness and mortality in people with Type 1 diabetes mellitus. Infrared thermographic assessment of changes in skin temperature during hypoglycaemia in patients with type 1 diabetes. Magnetic resonance imaging reveals altered distribution of hepatic fat in children with type 1 diabetes compared to controls. Effect of vitamin E supplementation on HDL function by haptoglobin genotype in type 1 diabetes: results from the HapE randomized crossover pilot trial. Treatment of diabetes with encapsulated pig islets: an update on current developments. Free full text available in HTML and PDF formats. Behavioral economics survey of patients with […]

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Research News From May 20, 2015

Stem cells for the cell and molecular therapy of type 1 diabetes mellitus (T1D): the gap between dream and reality. Free full text available in HTML and PDF formats. Efficacy and Safety of LY2963016 Insulin Glargine Compared with Insulin Glargine (Lantus�) in Patients with Type 1 Diabetes in a Randomised Controlled Trial (The ELEMENT 1 Study). Glycated albumin and the risk of micro- and macrovascular complications in subjects with Type 1 Diabetes. Free full text available in HTML and PDF formats. Lipid peroxidation and antioxidant protection in girls with type 1 diabetes mellitus during reproductive system development. Free full text […]

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Research News From May 13, 2015

Effects of high-dose oral insulin on immune responses in children at high risk for type 1 diabetes: the Pre-POINT randomized clinical trial. A model for the role of gut bacteria in the development of autoimmunity for type 1 diabetes.

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Research News From May 6, 2015

Glucose-responsive insulin activity by covalent modification with aliphatic phenylboronic acid conjugates. See also Experimental ‘Smart’ Insulin Shows Promise in Mice: Study. In-silico Closed Loop Control Validation Studies for Optimal Insulin Delivery in Type 1 Diabetes. Clinical results of islet transplantation.

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Research News From April 29, 2015

Clinical Results of an Automated Artificial Pancreas Using Technosphere Inhaled Insulin to Mimic First-Phase Insulin Secretion. Type 1 diabetes: A predictable disease. Free full text available in HTML and PDF formats. Efficacy of a long-acting c-peptide analogue against peripheral neuropathy in streptozotocin-diabetic mice. Glycemia, Hypoglycemia, and Costs of Simultaneous Islet-Kidney or Islet After Kidney Transplantation Versus Intensive Insulin Therapy and Waiting List for Islet Transplantation. White matter hyperintensities in middle-aged adults with childhood-onset type 1 diabetes. Living Donor Kidney Transplantation Preceding Pancreas Transplantation Reduces Mortality in Type 1 Diabetics With End-stage Renal Disease. Straylight, lens yellowing and aberrations of eyes […]

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Research News From April 22, 2015

A prevascularized subcutaneous device-less site for islet and cellular transplantation. Effects of High-Dose Oral Insulin on Immune Responses in Children at High Risk for Type 1 Diabetes. Daycare attendance, breastfeeding, and the development of type 1 diabetes: the diabetes autoimmunity study in the young. Free full text available in HTML and PDF formats. Environmental Trigger(s) of Type 1 Diabetes: Why So Difficult to Identify? Free full text available in HTML and PDF formats. Can Exposure to Environmental Chemicals Increase the Risk of Diabetes Type 1 Development? Free full text available in HTML and PDF formats. Unraveling the Hygiene Hypothesis of […]

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