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Research News From April 15, 2015

Experience of a serious life event increases the risk for childhood type 1 diabetes: the ABIS population-based prospective cohort study. See also Serious life events in childhood can triple risk of developing type 1 diabetes. Global epidemiology of type 1 diabetes in young adults and adults: a systematic review. Free full text available in HTML and PDF formats. Continuous Intraperitoneal Insulin Infusion Versus Subcutaneous Insulin Therapy in the Treatment of Type 1 Diabetes: Effects on Glycemic Variability. Assessment of the relationship between hypoglycaemia awareness and autonomic function following islet cell/pancreas transplantation. Corneal Confocal Microscopy Detects Neuropathy in Patients with Type […]

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Research News From April 8, 2015

Efficacy and safety of the glucagon-like peptide-1 receptor agonist liraglutide added to insulin therapy in poorly regulated patients with type 1 diabetes-a protocol for a randomised, double-blind, placebo-controlled study: The Lira-1 study will add to the knowledge of the use of GLP-1 receptor agonists in people with type 1 diabetes. Sodium glucose transporter 2 (sglt2) inhibitors: Current status in clinical practice. Perinatal and childhood risk factors for early-onset type 1 diabetes: a population-based case-control study in Taiwan. Lower serum 25 (OH) D concentrations in type 1 diabetes: A meta-analysis.

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Research News From April 2, 2015

Validity of animal models of type 1 diabetes, and strategies to enhance their utility in translational research. Bioengineered stem cells as an alternative for islet cell transplantation. Free full text available in HTML and PDF formats. Epidemiologic Features of Type 1 Diabetic Patients between 0 and 18 Years of Age in İstanbul City. Low mean temperature rather than few sunshine hours are associated with an increased incidence of type 1 diabetes in children.

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Research News From March 25, 2015

Less Is More: The Detrimental Consequences of Immunosuppressive Therapy in the Treatment of Type-1 Diabetes.

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Research News From March 18, 2015

CGM-measured glucose values have a strong correlation with C-peptide, HbA1c and IDAAC, but do poorly in predicting C-peptide levels in the two years following onset of diabetes. A Reassessment of the Survival Advantage of Simultaneous Kidney-Pancreas Versus Kidney-Alone Transplantation.

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Research News From March 11, 2015

An economic analysis of autologous hematopoietic stem cell transplantation (AHSCT) in the treatment of new onset type 1 diabetes.

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Research News From March 4, 2015

Changes in beta cell function during the proximate post-diagnosis period in persons with type 1 diabetes. Complication characteristics between young-onset type 2 versus type 1 diabetes in a UK population. Free full text available in HTML and PDF formats.

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Research News From February 25, 2015

T1D Exchange Presents Data on New Form of Glucagon “Rescue” Treatment for Severe Hypoglycemia. Glucagon receptor antibody completely suppresses type 1 diabetes phenotype without insulin by disrupting a novel diabetogenic pathway. Effects of sitagliptin on counterregulatory and incretin hormones during acute hypoglycaemia in patients with type 1 diabetes: a randomized double blind placebo-controlled cross-over study. The Dynamics of the Human Infant Gut Microbiome in Development and in Progression toward Type 1 Diabetes. Microfabricated microporous membranes reduce the host immune response and prolong the functional lifetime of a closed-loop insulin delivery implant in a type 1 diabetic rat model. In Vivo […]

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Research News From February 11, 2015

Glucose-responsive insulin activity by covalent modification with aliphatic phenylboronic acid conjugates. See also Engineered insulin could offer better diabetes control, ‘Smart’ insulin hope for diabetes, and ‘Smart’ insulin may ease burden of type 1 diabetes patients, research suggests. Predictors of Progression From the Appearance of Islet Autoantibodies to Early Childhood Diabetes: The Environmental Determinants of Diabetes in the Young (TEDDY). Insulin detemir is transported from blood to cerebrospinal fluid and has prolonged central anorectic action relative to NPH insulin. Glycemic Control in Simultaneous Islet-Kidney Versus Pancreas-Kidney Transplantation in Type 1 Diabetes: A Prospective 13-Year Follow-up. Noninvasive mapping of pancreatic inflammation […]

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Research News From February 6, 2015

Beta Cell death and dysfunction during type 1 diabetes development in at-risk individuals. Future Artificial Pancreas Technology for Type 1 Diabetes: What Do Users Want? Mesenchymal stem cells derived in vitro transdifferentiated insulin-producing cells: A new approach to treat type 1 diabetes. Free full text available in HTML format. The incidence of type 1 diabetes is still increasing in The Netherlands, but has stabilised in children under five (Young DUDEs-1). Diabetes in rats treated with engineered probiotic and Behind the headlines: a probiotic cure for diabetes? report on Engineered Commensal Bacteria Reprogram Intestinal Cells Into Glucose-Responsive Insulin-Secreting Cells for the […]

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