icon-circle-smiley-face

News Links

Research News From January 28, 2015

Multicenter outpatient dinner/overnight reduction of hypoglycemia and increased time of glucose in target with a wearable artificial pancreas using modular model predictive control in adults with type 1 diabetes. Psychosocial aspects of closed- and open-loop insulin delivery: closing the loop in adults with Type 1 diabetes in the home setting. Engineered Commensal Bacteria Reprogram Intestinal Cells Into Glucose-Responsive Insulin-Secreting Cells for the Treatment of Diabetes. Beta-cell destruction and preservation in childhood and adult onset type 1 diabetes. Bariatric surgery and diabetes: Implications of type 1 versus insulin-requiring type 2. The advanced glycation end product methylglyoxal-derived hydroimidazolone-1 and early signs of […]

Read More

Research News From January 21, 2015

Multinight “Bedside” Closed-Loop Control for Patients with Type 1 Diabetes. Performance and Acceptability of a Combined Device for Insulin Infusion and Glucose Sensing in the Home Setting. Diazoxide improves hormonal counterregulatory responses to acute hypoglycemia in long-standing Type 1 Diabetes. Preexisting Insulin Autoantibodies Predict Efficacy of Otelixizumab in Preserving Residual beta-Cell Function in Recent-Onset Type 1 Diabetes.

Read More

Research News From December 31, 2014

Bacteroides dorei dominates gut microbiome prior to autoimmunity in Finnish children at high risk for type 1 diabetes. The influence of glucagon on postprandial hyperglycaemia in children 5 years after onset of type 1 diabetes. Trends in Childhood Type 1 Diabetes Mellitus Incidence in Beijing from 1995 to 2010: A Retrospective Multicenter Study Based on Hospitalization Data. Tolerance Induction and Reversal of Diabetes in Mice Transplanted with Human Embryonic-Stem-Cell-Derived Pancreatic Endoderm.

Read More

Research News From December 24, 2014

Most People With Long-Duration Type 1 Diabetes in a Large Population-Based Study Are Insulin Microsecretors. See also One in Every Three People with Type 1 Diabetes Produces Insulin Years Post-Diagnosis Largest Study to Date of Residual Insulin Production Proves Such Patients Are Not ‘Exceptional’; Major Clinical and Health Policy Implications. Prevalence of Detectable C-peptide According to Age at Diagnosis and Duration of Type 1 Diabetes. Anti-thymocyte globulin/G-CSF treatment preserves beta cell function in patients with established type 1 diabetes. Early Childhood Gut Microbiomes Show Strong Geographic Differences Among Subjects at High Risk for Type 1 Diabetes. Autoantibody-defined risk for Type […]

Read More

Research News From December 17, 2014

Unsupervised home use of overnight closed-loop system over 3 to 4 weeks – Pooled analysis of randomized controlled studies in adults and adolescents with type 1 diabetes. Longitudinal Assessment of Neuroanatomical and Cognitive Differences in Young Children with Type 1 Diabetes: Association with Hyperglycemia. Is There a Link Between Liraglutide and Pancreatitis? A Post Hoc Review of Pooled and Patient-Level Data From Completed Liraglutide Type 2 Diabetes Clinical Trial. Reduced Ki67 staining in the postmortem state calls into question past conclusions about the lack of turnover of adult human beta cells.

Read More

Research News From December 10, 2014

‘Diabetes: a cure at last’ or just hype? Closing the loop overnight at home setting: psychosocial impact for adolescents with type 1 diabetes and their parents. Free full text available in HTML and PDF formats. Sodium-glucose cotransporter-2 inhibition and the potential for renal protection in diabetic nephropathy.

Read More

Research News From December 3, 2014

Comparison of dual-hormone artificial pancreas, single-hormone artificial pancreas, and conventional insulin pump therapy for glycaemic control in patients with type 1 diabetes: an open-label randomised controlled crossover trial. Assessing Sensor Accuracy for Non-Adjunct Use of Continuous Glucose Monitoring. Cesarean Section and Chronic Immune Disorders. Enterovirus persistence as a mechanism in the pathogenesis of type 1 diabetes. Enteroviruses, hygiene and type 1 diabetes: toward a preventive vaccine. Comparison of breath gases, including acetone, with blood glucose and blood ketones in children and adolescents with type 1 diabetes.

Read More

Research News From November 26, 2014

Infant Feeding in Relation to Islet Autoimmunity and Type 1 Diabetes in Genetically Susceptible Children: The MIDIA Study. Free full text available in PDF format. Demonstration of an Intrinsic Relationship Between Endogenous C-peptide Concentration and Determinants of Glycemic Control in Type 1 Diabetes Following Islet Transplantation. Free full text available in PDF format. Detection of a low-grade enteroviral infection in the islets of Langerhans of living patients newly diagnosed with type 1 diabetes. Islet autoantibody status in a multi-ethnic UK clinic cohort of children presenting with diabetes. Free full text available in HTML and PDF formats. A Modified Method of […]

Read More

Research News From November 19, 2014

Nonhuman Primate Models of Type 1 Diabetes Mellitus for Islet Transplantation. Free full text available in HTML and PDF formats. NGAL and cystatin C: two possible early markers of diabetic nephropathy in young patients with type 1 diabetes mellitus: one year follow up. The gut microbiota modulates glycaemic control and serum metabolite profiles in non-obese diabetic mice. Free full text available in HTML and PDF formats.

Read More

Research News From November 12, 2014

Increasing trends in the incidence and prevalence rates of type 1 diabetes among children and adolescents in the Netherlands. Incidence of type 1 diabetes among Polish children ages 0-14 years from 1989-2012. A preclinical study on the efficacy and safety of a new vaccine against Coxsackievirus B1 reveals no risk for accelerated diabetes development in mouse models. A Method for Gene-Based Pathway Analysis Using Genomewide Association Study Summary Statistics Reveals Nine New Type 1 Diabetes Associations.

Read More