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Research News From November 5, 2014

Major Advance for Diabetes Stem Cell Therapy? Use of an artificial pancreas among adolescents for a missed snack bolus and an underestimated meal bolus. cprThe FGF21 analogue, LY2405319, lowers blood glucose in streptozotocin-induced insulin-deficient diabetic mice by restoring brown adipose tissue function. Docosahexaenoic acid has an anti-diabetic effect in streptozotocin-induced diabetic mice. Free full text available in HTML and PDF formats.

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Research News From October 29, 2014

The Betatrophin Blues. One year remission of type 1 diabetes mellitus in a patient treated with sitagliptin. Free full text available in HTML and PDF formats. Increased Immune Cell Infiltration of the Exocrine Pancreas: A Possible Contribution to the Pathogenesis of Type 1 Diabetes. Losing a Grip on the Notion of β-Cell Specificity for Immune Responses in Type 1 Diabetes: Can We Handle the Truth? Free full text available in PDF format. Enterovirus infection is associated with an increased risk of childhood type 1 diabetes in Taiwan: a nationwide population-based cohort study. Type 1 Diabetes Surges In White Kids.

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Research News From October 22, 2014

A Novel Method to Detect Pressure-Induced Sensor Attenuations (PISA) in an Artificial Pancreas. Seasonal variation in month of diagnosis in children with type 1 diabetes registered in 23 European centers during 1989-2008: little short-term influence of sunshine hours or average temperature. The Raikas – a unique combination of high prevalence of type 1 diabetes susceptibility genes and near zero incidence of the disease. Prognostic value of endothelial dysfunction in type 1 diabetes mellitus. Free full text available in HTML and PDF formats. Do We Need Worms to Promote Immune Health?

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Research News From October 15, 2014

Generation of Functional Human Pancreatic β Cells In Vitro. See also From stem cells to billions of human insulin-producing cells and Scientist hopes stem cells will lead to diabetes cure. FOXO1 inhibition yields functional insulin-producing cells in human gut organoid cultures. See also It May Take Guts to Cure Diabetes. Time Lag of Glucose From Intravascular to Interstitial Compartment in Type 1 Diabetes. Absence of Glucagon and Insulin Action Reveals a Role for the Glucagon-like Peptide-1 Receptor in Endogenous Glucose Production. Estimated insulin sensitivity predicts regression of albuminuria in Type 1 diabetes. Life expectancy of people with type 1 diabetes […]

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Research News From October 8, 2014

Antibodies to islet cell autoantigens, rotaviruses and/or enteroviruses in cord blood and healthy mothers in relation to the 2010-2011 winter viral seasons in Israel: a pilot study. See also Viral Infection May Trigger Childhood Diabetes in Utero. Design and in silico evaluation of an intraperitoneal-subcutaneous (IP-SC) artificial pancreas. Does Insulin Therapy for Type 1 Diabetes Mellitus Protect Against Alzheimer’s Disease? Microneedles for Drug Delivery via the Gastrointestinal Tract. Full text PDF available via link. See also New drug-delivery capsule may replace injections. Clinical and molecular characterization of maturity onset-diabetes of the young caused by hepatocyte nuclear factor-4 alpha mutation: red […]

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Research News From October 1, 2014

Exploring the Potential of the SGLT2 Inhibitor Dapagliflozin in Type 1 Diabetes: A Randomized, Double-Blind, Placebo-Controlled Pilot Study. Inpatient Trial of an Artificial Pancreas Based on Multiple Model Probabilistic Predictive Control with Repeated Large Unannounced Meals. Factors affecting the success of glucagon delivered during an automated closed-loop system in type 1 diabetes. A Novel, Stable, Aqueous Glucagon Formulation Using Ferulic Acid as an Excipient. Obesity, islet cell autoimmunity and cardiovascular risk factors in youth at onset of type 1 autoimmune diabetes.

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Research News From September 24, 2014

The Impact of Accelerometer Use in Exercise-Associated Hypoglycemia Prevention in Type 1 Diabetes. Occurrence of Increased Arterial Stiffness in a Cohort of Adult Patients With Type 1 Diabetes Mellitus When Compared to Normoglycemic Controls. Helminth Infections Decrease Host Susceptibility to Immune-Mediated Diseases. (See also Helminths in Wikipedia.) C-peptide replacement therapy as an emerging strategy for preventing diabetic vasculopathy. Probiotics Cut Autoimmunity 33% in Infants at Risk for Diabetes. Did you get the full story about artificial sweeteners and diabetes?

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Research News From September 17, 2014

Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells. A Remote Monitoring System for Artificial Pancreas Support Is Safe, Reliable, and User Friendly. Poor Glycemic Control is Associated with Reduced Prostate-Specific Antigen Concentrations in Men with Type 1 Diabetes. Nine-year longitudinal study of cardiovascular risk factors in Spanish children and adolescents with type 1 diabetes. Polymorphism of the FTO Gene Influences Body Weight in Children with Type 1 Diabetes without Severe Obesity. Free full text available in HTML and PDF formats. New Insulin Glargine 300 units�mL−1 Provides a More Even Activity Profile and Prolonged Glycemic […]

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Research News From September 10, 2014

Assessing the effectiveness of 3 months day and night home closed-loop insulin delivery in adults with suboptimally controlled type 1 diabetes: a randomised crossover study protocol. Free full text available in HTML and PDF formats. Multicenter Closed-Loop/Hybrid Meal Bolus Insulin Delivery with Type 1 Diabetes. Effect of Intensive Diabetes Therapy on the Progression of Diabetic Retinopathy in Patients with Type 1 Diabetes: 18 Years of Follow-up in the DCCT/EDIC. Sodium-Glucose Cotransporter 2 Inhibition in Type 1 Diabetes: Simultaneous Glucose Lowering and Renal Protection? The Relative Effectiveness of Pumps Over MDI and Structured Education (REPOSE): study protocol for a cluster randomised controlled […]

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Research News From September 3, 2014

Can Executive Impairments be Precipitated by Excessive Glycemic Fluctuations in Early Onset Type 1 Diabetes Mellitus? A Case Study. Higher dietary salt intake is associated with microalbuminuria, but not with retinopathy in individuals with type 1 diabetes: the EURODIAB Prospective Complications Study.

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