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Research News From April 2, 2014

Inhaled Insulin Clears Hurdle Toward F.D.A. Approval. Can Glucose Be Monitored Accurately at the Site of Subcutaneous Insulin Delivery? Free full text available in HTML and PDF formats. A Novel Algorithm for Prediction and Detection of Hypoglycemia Based on Continuous Glucose Monitoring and Heart Rate Variability in Patients With Type 1 Diabetes. Free full text available in HTML and PDF formats. Gut Microbe ‘Cross Talk’ in Early Life and Type 1 Diabetes. (Free Medscape membership required) Insulin-Producing Intestinal K Cells Protect NOD Mice from Autoimmune Diabetes. Hypoglycaemia and QT interval prolongation in type 1 diabetes – bridging the gap between […]

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Research News From March 27, 2014

Viruses and Type 1 diabetes: a dynamic labile equilibrium. Free full text available in HTML and PDF formats. Post-breakfast closed-loop glucose control is improved when accompanied with carbohydrate-matching bolus compared to weight-dependent bolus. Population-based incidence of diabetes in Australian youth aged 10-18 yr: increase in type 1 diabetes but not type 2 diabetes. Residual C-peptide in type 1 diabetes: what do we really know? Exploratory Trial of Intranasal Administration of Glucagon-like Peptide-1 in Japanese Patients With Type 2 Diabetes. Growth Abnormalities in Children with Type 1 Diabetes, Juvenile Chronic Arthritis, and Asthma. Free full text available in HTML and PDF […]

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Research News From March 19, 2014

HbA1c Variability as an Independent Risk Factor for Diabetic Retinopathy in Type 1 Diabetes: A German/Austrian Multicenter Analysis on 35,891 Patients. Free full text available in HTML and PDF formats. Glucose Sensing in the Peritoneal Space Offers Faster Kinetics than Sensing in the Subcutaneous Space. Improved pharmacokinetic and pharmacodynamic profile of insulin analogs using InsuPatch, a local heating device. Antithymocyte globulin treatment for patients with recent-onset type 1 diabetes: 12-month results of a randomised, placebo-controlled, phase 2 trial. Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled […]

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Research News From March 12, 2014

Compromised gut microbiota networks in children with anti-islet cell autoimmunity. The human GLP-1 analogs liraglutide and semaglutide: Absence of histopathological effects on the pancreas in nonhuman primates. GAD Autoantibody Affinity in Adult Patients With Latent Autoimmune Diabetes, the Study Participants of a GAD65 Vaccination Trial. Subclinical Vascular Endothelial Dysfunctions and Myocardial Changes With Type 1 Diabetes Mellitus in Children and Adolescents. Genome-wide association study of urinary albumin excretion rate in patients with type 1 diabetes. Adaptive calibration algorithm for plasma glucose estimation in continuous glucose monitoring.

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Research News From March 5, 2014

Sodium-Glucose Cotransporter 2 Inhibition and Glycemic Control in Type 1 Diabetes: Results of an 8-Week Open-Label Proof-of-Concept Trial. Combination therapy for preservation of beta cell function in Type 1 diabetes: New attitudes and strategies are needed! The University of Virginia/Padova Type 1 Diabetes Simulator Matches the Glucose Traces of a Clinical Trial. Bringing closed-loop home: recent advances in closed-loop insulin delivery. Investigational new insulin glargine 300 U.mL has the same metabolism as insulin glargine 100 U.mL. Long-term survival after simultaneous pancreas-kidney transplantation with primary function of at least one year – a single-center experience.

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Research News From February 26, 2014

Changes in human brain glutamate concentration during hypoglycemia: insights into cerebral adaptations in hypoglycemia-associated autonomic failure in type 1 diabetes. A type I interferon transcriptional signature precedes autoimmunity in children genetically at-risk of type 1 diabetes. Alpha1-Antitrypsin Therapy Downregulates Toll Like Receptor-Induced IL-1(beta) Responses in Monocytes and Myeloid Dendritic Cells and may Improve Islet Function in Recently Diagnosed Patients with Type 1 Diabetes. See also First Clinical Trial of Type 1 Diabetes Treatment Developed By BGU Researcher Has Extremely Positive Results. Motor unit number estimations are smaller in children with type 1 diabetes mellitus. A case-cohort study. Adolescents with clinical […]

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Research News From February 19, 2014

Innate immune activity is detected prior to seroconversion in children with HLA-conferred type 1 diabetes susceptibility. Treatment of new onset type 1 diabetes with teplizumab : successes and pitfalls in development. Localizing Functional Damage in the Neural Retina of Adolescents and Young Adults with Type 1 Diabetes.

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Research News From February 12, 2014

Treating diabetes with islet transplantation: Lessons from the past decade in Lille.

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Research News From February 5, 2014

Differences in the gut microbiota of healthy children and those with type 1 diabetes. Autonomous and continuous adaptation of a bihormonal bionic pancreas in adults and adolescents with type 1 diabetes. Clinical Evaluation of an Automated Artificial Pancreas Using Zone-Model Predictive Control and Health Monitoring System. Perioperative intensive insulin therapy using an artificial endocrine pancreas with closed-loop glycemic control system: the effects of no hypoglycemia. The effect of empagliflozin on arterial stiffness and heart rate variability in subjects with uncomplicated type 1 diabetes mellitus. Free full text available in PDF format. Evaluating the diet of children at increased risk for […]

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Research News From January 29, 2014

The effect of childhood cow’s milk intake and HLA-DR genotype on risk of islet autoimmunity and type 1 diabetes: The Diabetes Autoimmunity Study in the Young. Consumption of Acidic Water Alters the Gut Microbiome and Decreases the Risk of Diabetes in NOD Mice. Free full text available in HTML and PDF formats. Fecal microbiota imbalance in Mexican children with type 1 diabetes.. Free full text available in HTML and PDF formats. The PILGRIM Study: In Silico Modeling of a Predictive Low Glucose Management System and Feasibility in Youth with Type 1 Diabetes During Exercise.

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