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Research News From November 27, 2013

Systematically in silico comparison of unihormonal and bihormonal artificial pancreas systems. Free full text available in HTML and PDF formats. Assessment of Type 1 Diabetes Risk Conferred by HLA-DRB1, INS-VNTR and PTPN22 Genes Using the Bayesian Network Approach. Free full text available in HTML and PDF formats. Generation of Functional Insulin-Producing Cells from Neonatal Porcine Liver-Derived Cells by PDX1/VP16, BETA2/NeuroD and MafA. Free full text available in HTML and PDF formats.

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Research News From November 20, 2013

Feasibility of a Portable Bihormonal Closed-Loop System to Control Glucose Excursions at Home Under Free-Living Conditions for 48 Hours. Temporal intra-individual variation of immunological biomarkers in type 1 diabetes patients: implications for future use in cross-sectional assessment. Free full text available in HTML and PDF formats. Recruitment and retention of participants for an international type 1 diabetes prevention trial: A coordinators’ perspective. Vitamin D at the onset of type 1 diabetes in Italian children. Low incidence of spontaneous type 1 diabetes in non-obese diabetic mice raised on gluten-free diets is associated with changes in the intestinal microbiome. Free full text […]

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Research News From November 13, 2013

Early onset of diabetes in the proband is the major determinant of risk in HLA DR3-DQ2/DR4-DQ8 siblings. Autoimmune disorders and quadrivalent human papillomavirus vaccination of young female subjects. Islet cell antibodies (ICA) identify autoimmunity in children with new onset diabetes mellitus negative for other islet cell antibodies. The Association between Vitamin D and Vascular Stiffness in Adolescents with and without Type 1 Diabetes. Free full text available in HTML and PDF formats. Treatment of Autoimmune Diabetes by Inhibiting the Initial Event. Free full text available in HTML and PDF formats. Occurrence of Spontaneous Pancreatic Lesions in Normal and Diabetic Rats: […]

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Research News From November 6, 2013

Transplantation of human islets without immunosuppression. The trends and the risk of type 1 diabetes over the past 40 years: an analysis by birth cohorts and by parental migration background in Sweden. Free full text available in HTML and PDF formats. Genetic and Epigenetic Factors in Etiology of Diabetes Mellitus Type 1.

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Research News From October 30, 2013

Safety of Nighttime 2-Hour Suspension of Basal Insulin in Pump-Treated Type 1 Diabetes Even in the Absence of Low Glucose. Day and Night Closed-Loop Control in Adults With Type 1 Diabetes Mellitus. Artificial Pancreas Using a Personalized Rule-Based Controller Achieves Overnight Normoglycemia in Patients with Type 1 Diabetes. Incidence of type 1 diabetes in Norway among children aged 0-14 years between 1989 and 2012: has the incidence stopped rising? Results from the Norwegian Childhood Diabetes Registry. Neuroanatomical correlates of dysglycemia in young children with type 1 diabetes mellitus.

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Research News From October 23, 2013

Finnish team makes diabetes vaccine breakthrough, Key discovery raises hope of jab to beat diabetes, and New Evidence for Role of Specific Virus Causing Type 1 Diabetes reference Virus Antibody Survey in Different European Populations Indicates Risk Association Between Coxsackievirus B1 and Type 1 Diabetes, previously reported. Effectiveness of Early Intensive Therapy on beta-Cell Preservation in Type 1 Diabetes. Model-Based Closed-Loop Glucose Control in Type 1 Diabetes: The DiaCon Experience. Patterns of beta-Cell Autoantibody Appearance and Genetic Associations During the First Years of Life. Vitamin C Further Improves the Protective Effect of Glucagon-like Peptide-1 on Acute Hypoglycemia-Induced Oxidative Stress, Inflammation, […]

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Research News From October 15, 2013

The majority of patients with long-duration type 1 diabetes are insulin microsecretors and have functioning beta cells. Characterization of residual beta-cell function in long standing type 1 diabetes. Age-dependent decline of beta cell function in type 1 diabetes after diagnosis: a multi-centre longitudinal study. Early immunotherapy using autologous adult stem cells reversed the effect of anti-pancreatic islets in recently diagnosed type 1 diabetes mellitus: Preliminary results. Effect of a single autologous cord blood infusion on beta-cell and immune function in children with new onset type 1 diabetes: a non-randomized, controlled trial. Islet transplantation in type 1 diabetes: hype, hope and […]

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Research News From October 9, 2013

Impact of C-Peptide Preservation on Metabolic and Clinical Outcomes in the Diabetes Control and Complications Trial. Hyperglycemia following recovery from hypoglycemia worsens endothelial damage and thrombosis activation in type 1 diabetes and in healthy controls. Non-invasive detection of microvascular changes in a paediatric and adolescent population with type 1 diabetes: a pilot cross-sectional study. Free full text available in PDF format. Comparative effects of prolonged and intermittent stimulation of the glucagon-like peptide-1 receptor on gastric emptying and glycaemia.

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Research News From October 2, 2013

The Emerging Global Epidemic of Type 1 Diabetes. Increasing burden, younger age at onset and worst metabolic control in migrant than in Italian children with type 1 diabetes: an emerging problem in pediatric clinics. Do data in the literature indicate that glycaemic variability is a clinical problem? Glycaemic variability and vascular complications of diabetes.. Embedding islet in a liquid scaffold increases islet viability and function. Increased circulating levels of betatrophin in individuals with long-standing type 1 diabetes.

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Research News From September 25, 2013

Effect of Sensor-Augmented Insulin Pump Therapy and Automated Insulin Suspension vs Standard Insulin Pump Therapy on Hypoglycemia in Patients With Type 1 Diabetes. See also Low-Glucose-Suspension Feature Cuts Severe Hypoglycemia (Free Medscape membership required). Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial. See also Psoriasis drug shows promising results for treating type 1 diabetes. Infectious triggers in type 1 diabetes: is there a case for epitope mimicry? Large European study suggests men with type 1 diabetes are better at blood sugar control than […]

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