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Research News From September 18, 2013

Prevalence of Diabetes Mellitus in U.S. Youth in 2009: The SEARCH for Diabetes in Youth Study. Factors Associated with Maternal Reported Actions to Prevent Type 1 Diabetes in the First Year of the TEDDY Study. Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease. Age at first introduction to complementary foods is associated with sociodemographic factors in children with increased genetic risk of developing type 1 diabetes. The timing of introduction of complementary foods and later health. Early postnatal growth in children with HLA-conferred susceptibility to type 1 diabetes. Vitamin d […]

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Research News From September 4, 2013

C-peptide preserves the renal microvascular architecture in the streptozotocin-induced diabetic rat. Association between Vitamin D Metabolism Gene Polymorphisms and Risk of Islet Autoimmunity and Progression to Type 1 Diabetes: The Diabetes Autoimmunity Study in the Young (DAISY). Frontal gray matter atrophy in middle aged adults with type 1 diabetes is independent of cardiovascular risk factors and diabetes complications. The Systemic Immune Network in Recent Onset Type 1 Diabetes: Central Role of Interleukin-1 Receptor Antagonist (DIATOR Trial). Free full text available in HTML and PDF formats. Pharmacokinetics Modeling of Exogenous Glucagon in Type 1 Diabetes Mellitus Patients.

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Research News From August 28, 2013

Coxsackievirus B1 Is Associated With Induction of beta-Cell Autoimmunity That Portends Type 1 Diabetes. Determination of C-peptide in children: when is it useful? Effect of abatacept on immunogenicity of vaccines in individuals with type 1 diabetes. Key Protein Accelerates Diabetes in Two Ways. Heligmosomoides polygyrus infection reduces severity of type 1 diabetes induced by multiple low-dose streptozotocin in mice via STAT6- and IL-10-independent mechanisms. Diabetic Ketoacidosis at Diagnosis in Austrian Children: A Population-Based Analysis, 1989-2011. Time trends in mortality rates in type 1 diabetes from 2002 to 2011.

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Research News From August 21, 2013

Decreased cord-blood phospholipids in young age at onset type 1 diabetes. Night glucose control with MD-Logic artificial pancreas in home setting: a single blind, randomized crossover trial-interim analysis. Type 1 Diabetes Study Identifies Subset of Patients With Strong Response to Therapy. Physical Activity Measured by Physical Activity Monitoring System Correlates with Glucose Trends Reconstructed from Continuous Glucose Monitoring. Comparison of Physical Activity Sensors and Heart Rate Monitoring for Real-Time Activity Detection in Type 1 Diabetes and Control Subjects. Environmental determinants of islet autoimmunity (ENDIA): a pregnancy to early life cohort study in children at-risk of type 1 diabetes. Free full […]

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Research News From August 14, 2013

Advanced Glycation Endproducts in Children with Diabetes. Type 1 Diabetes Drug Proves Effective in Clinical Trial. Vitamin D deficiency is not associated with changes in retinal geometric parameters in young people with type 1 diabetes. Glycemic control in familial vs. sporadic type 1 diabetes patients over 5 years. Human Intestinal Microbiota and Type 1 Diabetes. Implanted islets in the anterior chamber of the eye are prone to autoimmune attack in a mouse model of diabetes. The levels of circulating TRAIL at the onset of type 1 diabetes are markedly decreased in patients with ketoacidosis and with the highest insulin requirement.

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Research News From August 7, 2013

Glucose-Responsive Microgels Integrated with Enzyme Nanocapsules for Closed-Loop Insulin Delivery. Risk factors and primary prevention trials for type 1 diabetes. Free full text available in HTML and PDF formats. Concordance of retinopathy and nephropathy over time in Type 1 diabetes: an analysis of data from the Diabetes Control and Complications Trial. Vitamin D in youth with Type 1 diabetes: prevalence of insufficiency and association with insulin resistance in the SEARCH Nutrition Ancillary Study. Insulin secretion and sensitivity in the prediction of type 1 diabetes in children with advanced beta-cell autoimmunity. Pediatric Diabetes Consortium Type 1 Diabetes New Onset (NeOn) Study: […]

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Research News From July 31, 2013

Outpatient Safety Assessment of an In-Home Predictive Low-Glucose Suspend System with Type 1 Diabetes Subjects at Elevated Risk of Nocturnal Hypoglycemia. Shaping the (auto)immune response in the gut: the role of intestinal immune regulation in the prevention of type 1 diabetes. Free full text available in HTML and PDF formats. Clinical and technical factors associated with skin intrinsic fluorescence in subjects with type 1 diabetes from the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study. The association between the HLA system and retinopathy development in patients with type 1 diabetes mellitus. Prevalence of Diagnosed and Undiagnosed Type […]

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Research News From July 24, 2013

Intraperitoneal insulin delivery to patients with type 1 diabetes results in higher serum IGF-I bioactivity than continuous subcutaneous insulin infusion. In Silico Design of Optimal Ratio for Co-Administration of Pramlintide and Insulin in Type 1 Diabetes. Does metformin improve vascular heath in children with type 1 diabetes? Protocol for a one year, double blind, randomised, placebo controlled trial. Free full text available in PDF format.

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Research News From July 17, 2013

Correction of Diabetic Hyperglycemia and Amelioration of Metabolic Anomalies by Minicircle DNA Mediated Glucose-Dependent Hepatic Insulin Production. Free full text available in HTML and PDF formats. Severe Hypoglycemia�Induced Lethal Cardiac Arrhythmias Are Mediated by Sympathoadrenal Activation. Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: Metabolic and immunologic features at baseline identify a subgroup of responders. Glucose-Responsive Microgels Integrated with Enzyme Nanocapsules for Closed-Loop Insulin Delivery. A Glucose Model Based on Support Vector Regression for the Prediction of Hypoglycemic Events Under Free-Living Conditions. Inflammatory biomarkers and progression of diabetic retinopathy […]

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Research News From July 3, 2013

Feasibility of Outpatient Fully Integrated Closed-Loop Control: First studies of wearable artificial pancreas. Nutritional Factors and Preservation of C-Peptide in Youth With Recently Diagnosed Type 1 Diabetes: SEARCH Nutrition Ancillary Study. Respiratory Infections in Early Life and the Development of Islet Autoimmunity in Children at Increased Type 1 Diabetes Risk. Evidence From the BABYDIET Study. see also Early Respiratory Infections Linked to Type 1 Diabetes Risk. The Prediction of Type 1 Diabetes by Multiple Autoantibody Levels and Their Incorporation Into an Autoantibody Risk Score in Relatives of Type 1 Diabetic Patients. The Association of Skin-Intrinsic Fluorescence With Type 1 Diabetes […]

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