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Research News From June 26, 2013

Teplizumab preserves C-peptide in recent-onset type 1 diabetes: 2-year results from the randomized, placebo-controlled Prot�g� trial. Threshold-Based Insulin-Pump Interruption for Reduction of Hypoglycemia. Free full text available in PDF format. HLA class II genotyping of African American type 1 diabetes patients reveals associations unique to African haplotypes.

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Research News From June 19, 2013

Seroconversion to Multiple Islet Autoantibodies and Risk of Progression to Diabetes in Children. See also Markers of Beta-Cell Dysfunction Associated With High Rate of Progression to Type 1 Diabetes and Blood Test May Predict Type 1 Diabetes in Children. Intrafamilial spread of enterovirus infections at the clinical onset of type 1 diabetes. Variations in rodent models of type 1 diabetes: islet morphology. Free full text available in HTML and PDF formats. An early warning system for hypoglycemic/hyperglycemic events based on fusion of adaptive prediction models.

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Research News From June 12, 2013

Persistent C-peptide: what does it mean? See also C-Peptide and its career from innocent bystander to active player in diabetic atherogenesis. Why is Type 1 Diabetes Increasing? The interplay between the gut microbiota and the immune system in the mechanism of type 1 diabetes. The case for virus-induced type 1 diabetes. Effects of triple antioxidant therapy on measures of cardiovascular autonomic neuropathy and on myocardial blood flow in type 1 diabetes: a randomised controlled trial. The use of intermediate endpoints in the design of type 1 diabetes prevention trials. Treating type 1 diabetes: from strategies for insulin delivery to dual […]

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Research News From June 5, 2013

Anti-CD3 clinical trials in type 1 diabetes mellitus. Human Umblical Cord Derived Mesenchymal Stem Cells Can Secret Insulin In Vitro and In Vivo. In antibody-positive first-degree relatives of patients with type 1 diabetes, HLA-A*24 and HLA-B*18, but not HLA-B*39, are predictors of impending diabetes with distinct HLA-DQ interactions. Time Trends and Gender Differences in Incidence and Prevalence of Type 1 Diabetes In Sweden.

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Research News From May 29, 2013

Recovery from Overt Type 1 Diabetes Ensues When Immune Tolerance and beta Cell Formation Are Coupled with Regeneration of Endothelial Cells in the Pancreatic Islets. Increased Brain Lactate Concentrations without Increased Lactate Oxidation during Hypoglycemia in Type 1 Diabetic Individuals. The Missing Heritability in T1D and Potential New Targets for Prevention. Free full text available in HTML and PDF formats. Extended family history of autoimmune diseases and phenotype and genotype of children with newly diagnosed type 1 diabetes. Genetically Engineered Human Islets Protected From CD8-mediated Autoimmune Destruction In Vivo. Vitamin D levels during and after resolution of ketoacidosis in children […]

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Research News From May 22, 2013

Serum concentrations of transforming growth factor-Beta 1 in predicting the occurrence of diabetic retinopathy in juvenile patients with type 1 diabetes mellitus. Free full text available in HTML and PDF formats. Hyperglycemia promotes myelopoiesis and impairs the resolution of atherosclerosis. Treatment of Diabetes and Diabetic Complications With a Ketogenic Diet. Calorimetric analysis of the plasma proteome: Identification of type 1 diabetes patients with early renal function decline. Renal Lesions Predict Progression of Diabetic Nephropathy in Type 1 Diabetes. Relation Between Ljungan Virus Antibodies, HLA-DQ8, and Insulin Autoantibodies in Newly Diagnosed Type 1 Diabetes Children. See also Ljungan virus is endemic […]

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Research News From May 8, 2013

The Ghrelin Agonist RM-131 Accelerates Gastric Emptying of Solids and Reduces Symptoms in Patients with Type 1 Diabetes Mellitus. Injectable Nano-Network for Glucose-Mediated Insulin Delivery. See also �Smart� Nanoparticles Can Now Control Blood Sugar in Diabetics for �Days at a Time� and Injectable Nano-Network Controls Blood Sugar in Diabetics for Days at a Time. Enhancement of In Vitro and In Vivo Function of Agarose Encapsulated Porcine Islets by Changes in the Islet Microenvironment. Low C-peptide levels and decreased expression of TNF and CD45 in children with high risk of type 1 diabetes. The influence of exposure to maternal diabetes in […]

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Research News From May 1, 2013

Autologous Umbilical Cord Blood (UCB) Infusion Followed by Oral Docosahexanoic Acid (DHA) and Vitamin D (VitD) Supplementation for C-Peptide Preservation in Children with Type 1 Diabetes (T1D). The Expression of Inflammatory Genes Is Upregulated in Peripheral Blood of Patients with Type 1 Diabetes. Improvement in beta-Cell Secretory Capacity Following Human Islet Transplantation According to the CIT07 Protocol. Glucose-Reducing Effect of the ORMD-0801 Oral Insulin Preparation in Patients with Uncontrolled Type 1 Diabetes: A Pilot Study. Temporal Trends of HLA, CTLA-4 and PTPN22 Genotype Frequencies among Type 1 Diabetes in Continental Italy. Free full text available in HTML and PDF formats. […]

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Research News From April 24, 2013

A review of artificial pancreas technologies with an emphasis on bi-hormonal therapy. Ranibizumab for edema of the macula in diabetes study: 3-year outcomes and the need for prolonged frequent treatment. Glucose-Reducing Effect of the ORMD-0801 Oral Insulin Preparation in Patients with Uncontrolled Type 1 Diabetes: A Pilot Study. Free full text available in HTML and PDF formats.

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Research News From April 17, 2013

Feasibility of Adjacent Insulin Infusion and Continuous Glucose Monitoring via the Medtronic Combo-Set. The Effects of Inpatient Hybrid Closed-Loop Therapy Initiated Within 1 Week of Type 1 Diabetes Diagnosis Diabetes Research in Children Network (DirecNet) and Type 1 Diabetes TrialNet Study Groups. Model-Based Sensor-Augmented Pump Therapy. Stable liquid glucagon formulations for rescue treatment and bi-hormonal closed-loop pancreas. How do childhood diagnoses of type 1 diabetes cluster in time? Free full text available in HTML and PDF formats. The role of vitamin d deficiency in the incidence, progression, and complications of type 1 diabetes mellitus. Free full text available in HTML […]

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