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Research News From April 10, 2013
Family psychological stress early in life and development of type 1 diabetes: The ABIS prospective study. Enteroviral pathogenesis of type 1 diabetes: queries and answers. Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials. Multivariable Adaptive Closed-Loop Control of an Artificial Pancreas Without Meal and Activity Announcement. Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming. Alteration of the thymic T cell repertoire by rotavirus infection is associated with delayed type 1 diabetes development in non-obese diabetic mice. Free full text available in HTML and PDF formats. Immunotherapy with Tolerogenic […]
Read MoreResearch News From April 3, 2013
Characteristics of rapid vs slow progression to type 1 diabetes in multiple islet autoantibody-positive children.
Read MoreResearch News From March 27, 2013
Faster pharmacokinetics and increased patient acceptance of intradermal insulin delivery using a single hollow microneedle in children and adolescents with type 1 diabetes. Circulating Vitamin D Metabolites and Subclinical Atherosclerosis in Type 1 Diabetes. Positron emission tomography measured cerebral blood flow and glucose metabolism are decreased in human type 1 diabetes. Protein intake in relation to risk of hypertension and microalbuminuria in patients with type 1 diabetes: the EURODIAB Prospective Complications Study. Baseline Markers of Inflammation Are Associated With Progression to Macroalbuminuria in Type 1 Diabetic Subjects. Factors associated with the presence of glutamic acid decarboxylase and islet antigen-2 autoantibodies […]
Read MoreResearch News From March 20, 2013
Population-based Survey of the Prevalence of Type 1 and Type 2 diabetes in School Children in Philadelphia. Addition of exenatide or sitagliptin to insulin in new onset type 1 diabetes: A randomized, open label study. Association of the incidence of type 1 diabetes with markers of infection and antibiotic susceptibility at country level. See also Global Rise in Type 1 Diabetes May Be Linked to Reduced Exposure to Pathogens in Early Life. Fasting and meal-stimulated residual beta cell function is positively associated with serum concentrations of proinflammatory cytokines and negatively associated with anti-inflammatory and regulatory cytokines in patients with longer […]
Read MoreResearch News From March 13, 2013
Can C-peptide mediated anti-inflammatory effects retard the development of microvascular complications of type 1 diabetes? In type 1 diabetes a subset of anti-coxsackievirus b4 antibodies recognize autoantigens and induce apoptosis of pancreatic Beta cells. Free full text available in HTML and PDF formats (link on HTML full text page). Maintaining functional islets through encapsulation in an injectable saccharide-peptide hydrogel. The Association between IgG4 Antibodies to Dietary Factors, Islet Autoimmunity and Type 1 Diabetes: The Diabetes Autoimmunity Study in the Young. Free full text available in HTML and PDF formats (link on HTML full text page). Glucose tolerance and beta-cell function […]
Read MoreResearch News From March 6, 2013
Nocturnal Glucose Control with an Artificial Pancreas at a Diabetes Camp. See also Artificial Pancreas Worked Overnight on Kids With Type 1 Diabetes. Overnight automated type 1 diabetes control under MD-logic closed-loop system: a randomized crossover trial. Does farm environment protect against type 1 diabetes mellitus? Free full text available in HTML and PDF formats. Identification of a SIRT1 Mutation in a Family with Type 1 Diabetes. See also First single gene mutation shown to result in type 1 diabetes and First Single Gene Mutation Shown to Result in Type 1 Diabetes. Treatment of diabetes mellitus with microencapsulated fetal human […]
Read MoreResearch News From February 27, 2013
Gut microbiota in children with type 1 diabetes differs from that in healthy children: a case-control study. Free full text available in PDF format. Revisiting the notion of type 1 diabetes being a T-cell-mediated autoimmune disease. Immune Therapy and beta-Cell Death in Type 1 Diabetes. Reactivation of latent viruses in individuals receiving rituximab for new onset type 1 diabetes. Proinsulin/Insulin Autoantibodies Measured With Electrochemiluminescent Assay Are the Earliest Indicator of Prediabetic Islet Autoimmunity . More people needed for type 1 diabetes vaccine study.
Read MoreResearch News From February 20, 2013
Allogeneic Bone Marrow Cocultured With Human Islets Significantly Improves Islet Survival and Function In Vivo. Human milk can neutralize Coxsackievirus B4 in vitro. Promotion of Autoimmune Diabetes by Cereal Diet in the Presence or Absence of Microbes Associated With Gut Immune Activation, Regulatory Imbalance, and Altered Cathelicidin Antimicrobial Peptide.
Read MoreResearch News From February 13, 2013
Treatment of Diabetes and Long-term Survival Following Insulin and Glucokinase Gene Therapy. See also UAB researchers cure type 1 diabetes in dogs, Type 1 Diabetes Cured In Dogs, and Type 1 Diabetes Cured in Dogs, Study Suggests. Differences in glucose-stimulated insulin secretion in vitro of islets from human, nonhuman primate, and porcine origin. Efficacy and Safety of Insulin Degludec in a Flexible Dosing Regimen vs Insulin Glargine in Patients With Type 1 Diabetes (BEGIN: Flex T1): A 26-Week Randomized, Treat-to-Target Trial With a 26-Week Extension. Evidence of Association between Type 1 Diabetes and Exposure to Enterovirus in Cuban Children and […]
Read MoreResearch News From February 6, 2013
Glucose-responsive insulin and glucagon delivery (dual-hormone artificial pancreas) in adults with type 1 diabetes: a randomized crossover controlled trial. Free full text available in PDF format. Preclinical Serum 25-Hydroxyvitamin D Levels and Risk of Type 1 Diabetes in a Cohort of US Military Personnel. See also �Sunshine vitamin� looks a little brighter. HLA Class I and II Alleles are Associated with Microvascular Complications of Type 1 Diabetes. PDX1-engineered embryonic stem cell-derived insulin producing cells regulate hyperglycemia in diabetic mice. Free full text available in HTML and PDF formats.
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