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Research News From May 6, 2007

Insulin dependant diabetes mellitus: implications for male reproductive function. See also Diabetes may cut male fertility and Diabetes Damages DNA In Men’s Sperm And May Affect Fertility, According To Study. Intracoronary ultrasound examinations reveal significantly more advanced coronary atherosclerosis in people with type 1 diabetes than in age- and sex-matched non-diabetic controls. A Rho-kinase inhibitor, fasudil, prevents development of diabetes and nephropathy in insulin-resistant diabetic rats. Two-week treatment with pravastatin improves ventriculo-vascular haemodynamic interactions in young men with type 1 diabetes. Conversion of embryonic stem cells into pancreatic beta-cell surrogates guided by ontogeny. Sleep deprivation reduces the lymphocyte count in […]

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Research News From April 29, 2007

Inhibition of autoimmune diabetes by oral administration of anti-CD3 monoclonal antibody. Rising Incidence of Type 2 Diabetes in Children in the U.K. Marked increase in type 1 diabetes mellitus incidence in children aged 0-14 yr in Victoria, Australia, from 1999 to 2002. Perinatal risk factors for childhood Type 1 diabetes in Western Australia�a population-based study (1980�2002). Steep increase of incidence of childhood diabetes since 1999 in Austria. Time trend analysis 1979-2005. A nationwide study. Incidence of type 1 diabetes mellitus in the 0- to 17-yr-old Israel population, 1997-2003. Association of immune mediators at diagnosis of Type 1 diabetes with later […]

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Research News From April 22, 2007

Mutations in KATP Channel Genes cause Transient Neonatal Diabetes and Permanent Diabetes in Childhood or Adulthood. Early infancy onset of type 1A diabetes mellitus in dizygotic twins: association with genetic and environmental factors. Free Portuguese language full text available in HTML and PDF formats. Brief Hyperglycaemia In The Early Pregnant Rat Increases Fetal Weight At Term By Stimulating Placental Growth And Affecting Placental Nutrient Transport.

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Research News From April 15, 2007

Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation in Newly Diagnosed Type 1 Diabetes Mellitus. Free full text available in HTML and PDF formats. See also Type I diabetics live without insulin in stem cell experiment and Stem cells re-set the immune systems of diabetes patients. Association between glycosylated hemoglobin level and 16-year incidence of chronic kidney disease in type 1 diabetes. Changes in Depressive Symptoms and Glycemic Control in Diabetes Mellitus. Rotavirus infection of infant and young adult nonobese diabetic mice involves extraintestinal spread and delays diabetes onset. Relationship between interstitial and blood glucose in type 1 diabetes patients: delay and […]

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Research News From April 8, 2007

Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase. Free full text available in PDF format. See also Hypoglycemia, functional brain failure, and brain death and Glucose Triggers Brain Cell Death In Rats After Hypoglycemic Coma. Moving towards efficient therapies in type 1 diabetes: To combine or not to combine? Shorter remission period in young versus older children with diabetes mellitus type 1. No evidence for increased self-reported cognitive failure in Type 1 and Type 2 diabetes: a cross-sectional study. Lack of evidence of hypervolemia in children with insulin-dependent diabetes mellitus. Perturbation of hyaluronan metabolism […]

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Research News From April 1, 2007

Live encapsulated porcine islets from a type 1 diabetic patient 9.5 yr after xenotransplantation. See also LCT Reports Major Step Forward for Islet Transplantation in Diabetes Patient, DiabeCell – Living Cell Technologies, and 10 years on, pig cells still fighting diabetes. Evaluation of promoters for driving efficient transgene expression in neonatal porcine islets. Glucose responsive insulin production from human embryonic germ (EG) cell derivatives. Islet cell transplantation today. Prediction and Prevention of Type 1 Diabetes: Progress, Problems, and Prospects. Association of immune mediators at diagnosis of Type 1 diabetes with later clinical remission. Spatiotemporal Trends and Age-Period-Cohort Modeling of the […]

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Research News From March 25, 2007

Glycaemic control, health status and treatment satisfaction with continuous intraperitoneal insulin infusion. Normalization of the IGF-IGFBP-axis by Sustained Nightly Insulinization in Type 1 Diabetes. Are Insights Gained From NOD Mice Sufficient To Guide Clinical Translation? Another Inconvenient Truth. Childhood obesity as a risk factor for diabetes mellitus type I: the accelerator hypothesis. Dendritic cells with TGF�-1 differentiate na�ve CD4+CD25� T cells into islet-protective Foxp3+ regulatory T cells. See also Successful Islet Cell Transplant Without Immunosuppressive Therapy In Mice With Type 1 Diabetes. Autoimmunity and beta cell regeneration in mouse and human Type 1 diabetes: The peace is not enough. Coxsackievirus […]

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Research News From March 18, 2007

Major childhood infectious diseases and other determinants associated with type 1 diabetes: a case-control study. Coxsackie B4 virus infection of {beta} cells and natural killer cell insulitis in recent-onset type 1 diabetic patients. Chemokines as drug targets in type 1 diabetes. Translational Mini-Review Series on Type 1 Diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes. Translational Mini-Review Series on Type 1 Diabetes: Immune-based therapeutic approaches for type 1 diabetes. Building a bridge between clinical and basic research: the phenotypic elements of familial predisposition to type 1 diabetes. MICA marks additional risk factors for Type 1 diabetes on extended […]

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Research News From March 11, 2007

Adaptive Closed-Loop Control Provides Blood-Glucose Regulation Using Dual Subcutaneous Insulin and Glucagon Infusion in Diabetic Swine. Microalbuminuria and the Risk for Early Progressive Renal Function Decline in Type 1 Diabetes. Vitamin D supplementation and diabetes-related autoimmunity in the ABIS study. Prevalence of atopy in children with type 1 diabetes mellitus in central Taiwan. HLA-DRB1*08 allele may help to distinguish between type 1 diabetes mellitus and type 2 diabetes mellitus in Mexican children. Selected immunologic and biochemical risk factors of the retinopathy and nephropathy development in children with diabetes mellitus type 1. Renal and retinal microangiopathy after 15 years of follow-up […]

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Research News From March 4, 2007

Increasing Incidence of Type 1 Diabetes in 0- to 17-Year-Old Colorado Youth. See also CU documents diabetes rise in kids. GAD Autoantibody Affinity and Epitope Specificity Identify Distinct Immunization Profiles in Children at Risk for Type 1 Diabetes. Simultaneous Control of Hyperglycemia and Oxidative Stress Normalizes Endothelial Function in Type 1 Diabetes. Glycemic and Risk Factor Control in Type 1 Diabetes – Results from 13,612 patients in a national diabetes register. NOS3 Polymorphisms Are Associated With Arterial Stiffness in Children With Type 1 Diabetes. Patients With Chronic Pancreatitis Have Islet Progenitor Cells in Their Ducts, but Reversal of Overt Diabetes […]

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