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Research News From December 17, 2006
TRPV1+ Sensory Neurons Control � Cell Stress and Islet Inflammation in Autoimmune Diabetes. Free full text available in HTML and PDF formats. See also Diabetes breakthrough; Toronto scientists cure disease in mice, Nervous system appears to play key role in developing Type 1 diabetes, Scientists make diabetes breakthrough in mice, and Type 1 Diabetes May Be Caused By Disruption of Link Between Nerve Cells and Beta Cells. Immune-neuroendocrine interactions and autoimmune diseases. Intranasal insulin administration: A method for dissociating central and peripheral effects of insulin. Children Diagnosed with Diabetes during Infancy Have Unique Clinical Characteristics. Insulin resistance in children and […]
Read MoreResearch News From December 10, 2006
Central Obesity, Incident Microalbuminuria, and Change in Creatinine Clearance in the Epidemiology of Diabetes Interventions and Complications Study concludes that “… waist circumference predicts the subsequent development of microalbuminuria in type 1 diabetes.” Predicting the Development of Macrovascular Disease in People with Type 1 Diabetes: A 9-Year Follow-up Study. Cardiovascular Risk Factors Predicting the Development of Distal Symmetrical Polyneuropathy in People with Type 1 Diabetes: A 9-Year Follow-up Study. Diabetic Neuropathy Differs in Type 1 and Type 2 Diabetes. Pancreatic autoantibodies in Italian patients with newly diagnosed type 1 diabetes mellitus over the age of 20 years. Inflammatory Process in […]
Read MoreResearch News From December 3, 2006
Feasibility of Automating Insulin Delivery for the Treatment of Type 1 Diabetes. Continuous glucose monitoring and external insulin pump: towards a subcutaneous closed loop. The Effect of Intensive Glycemic Treatment on Coronary Artery Calcification in Type 1 Diabetic Participants of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study. Inhalation of Human Insulin (Exubera) Augments the Efficiency of Muscle Glucose Uptake In Vivo. Protection from type 1 diabetes by vitamin d receptor haplotypes. Immunointervention in newly diagnosed type 1 diabetes. DiaPep277(R) Preserves Endogenous Insulin Production by Immunomodulation in Type 1 Diabetes. HLA Class I Epitope Discovery […]
Read MoreResearch News From November 26, 2006
New data from NIH lab confirms protocol to reverse type 1 diabetes in mice. However, see also Comment on Papers by Chong et al., Nishio et al., and Suri et al. on Diabetes Reversal in NOD Mice (PDF), Response to Comment on Chong et al. on Diabetes Reversal in NOD Mice (PDF), Response to Comment on Nishio et al. on Diabetes Reversal in NOD Mice (PDF), and Response to Comment on Suri et al. on Diabetes Reversal in NOD Mice (PDF). Multipotent stromal cells from human marrow home to and promote repair of pancreatic islets and renal glomeruli in diabetic […]
Read MoreResearch News From November 19, 2006
Evidence for immunological priming and increased frequency of CD4(+) CD25(+) cord blood T cells in children born to mothers with type 1 diabetes. Effect of heat shock protein peptide DiaPep277 on beta-cell function in paediatric and adult patients with recent-onset diabetes mellitus type 1: two prospective, randomized, double-blind phase II trials. Viral infections as potential triggers of type 1 diabetes. Diabetes mellitus and dementia.
Read MoreResearch News From November 12, 2006
QT(c) interval and resting heart rate as long-term predictors of mortality in type 1 and type 2 diabetes mellitus: a 23-year follow-up. Parental reactions to information about increased genetic risk of type 1 diabetes mellitus in infants. Seasonality of birth in children and young adults (0-29 years) with type 1 diabetes in Ukraine. The immunity during the pre-clinical period of type I diabetes mellitus. Patterns of growth among children who later develop type 2 diabetes or its risk factors. Association of amino-terminal-specific anti-glutamate decarboxylase (GAD65) autoantibodies with beta cell functional reserve and a milder clinical phenotype in patients with GAD65 […]
Read MoreResearch News From November 5, 2006
Lower levels of plasma 25-hydroxyvitamin D among young adults at diagnosis of autoimmune type 1 diabetes compared with control subjects: results from the nationwide Diabetes Incidence Study in Sweden (DISS). Maternal understanding of infant diabetes risk: Differential effects of maternal anxiety and depression. Metabolic factors affecting residual Beta cell function assessed by C-Peptide secretion in patients with newly diagnosed type 1 diabetes. Markers of absorption and synthesis of cholesterol in men with type 1 diabetes. Glucose-monitoring with continuous subcutaneous microdialysis in neonatal diabetes mellitus. Fuzzy-based controller for glucose regulation in type-1 diabetic patients by subcutaneous route. Partial versus Full Allogeneic […]
Read MoreResearch News From October 29, 2006
Does Coffee Consumption Reduce the Risk of Type 2 Diabetes in Individuals With Impaired Glucose? Incidence of Type 1 Diabetes in Philadelphia Is Higher in Black Than White Children From 1995 to 1999 – Epidemic or misclassification? Islet Autoimmunity in Children With Down�s Syndrome. Evaluation of a New Measure of Blood Glucose Variability in Diabetes. A multinational assessment of complications in type 1 diabetes: the DiaMond substudy of complications (DiaComp) level 1. Electrogastrography in children and adolescents with type 1 diabetes: Weak correlation with metabolic control parameters. Relationship between adiponectin levels, acylated ghrelin levels, and short-term body mass index changes […]
Read MoreResearch News From October 22, 2006
Normal but increasing hemoglobin A1c levels predict progression from islet autoimmunity to overt type 1 diabetes: Diabetes Autoimmunity Study in the Young (DAISY). Putting the pieces of the puzzle together – a series of hypotheses on the etiology and pathogenesis of type 1 diabetes. A genetic explanation for the rising incidence of type 1 diabetes, a polygenic disease. Islet antibodies associated with pancreatic B-cell dysfunction at and 3 years after diagnosis of diabetes in subjects aged 35�64 years old: degree of impairment less severe than in those aged 0�34 years old. Usefulness of colour tissue Doppler imaging in assessing aortic […]
Read MoreResearch News From October 15, 2006
Advances and Emerging Opportunities in Type 1 Diabetes Research will guide NIH research into type 1 diabetes. See also Plan Will Guide NIH Research in Type 1 Diabetes. Increased intestinal permeability precedes clinical onset of type 1 diabetes. Immune regulatory T cells in siblings of children suffering from type 1 diabetes mellitus. Incomplete penetrance of susceptibility genes for MHC-determined immunoglobulin deficiencies in monozygotic twins discordant for type 1 diabetes. Attitudes of genetic counselors towards expanding newborn screening and offering predictive genetic testing to children. Prevalence of Glutamic Acid Decarboxylase Antibody Positivity and its Association with Insulin Secretion and Sensitivity in […]
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