News Links

Reversal of Diabetes by Pancreatic Islet Transplantation into a Subcutaneous, Neovascularized Device. Low birth weight does not increase the risk of nephropathy in Finnish type 1 diabetic patients. The restorative effects of pulsed infrared light therapy on significant loss of peripheral protective sensation in patients with long-term type 1 and type 2 diabetes mellitus. Nicotinamide Reduces High Secretion of IFN-gamma in High-Risk Relatives Even Though It Does Not Prevent Type 1 Diabetes. Preserved sensitivity to {beta}2-adrenergic receptor agonists in patients with type 1 diabetes mellitus and hypoglycemia unawareness. Free full text available in PDF format. New Study Reveals Signaling Pathways […]

T Cell “Brakes” Lost During Human Evolution. Progress in islet transplantation in patients with type 1 diabetes mellitus. Renal transplantation in diabetic patients. Influence of pancreas and kidney transplant function on recipient survival. Evaluation of type 1 diabetics for simultaneous pancreas-kidney transplantation with regard to cardiovascular risk. Regulation of cerebral glucose metabolism. Changing cerebral blood flow velocity by transcranial Doppler during head up tilt in patients with diabetes mellitus. Human bone marrow mesenchymal stem cells transfected with human insulin genes can secrete insulin stably. Prolonged survival of allogeneic islets in cynomolgus monkeys after short-term anti-CD154-based therapy: nonimmunologic graft failure?

A cure for type 1 diabetes? references Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs, previously reported. Free full text available in PDF format. Current indications for pancreas or islet transplant. Comparison of 1-year patient and graft survival rates between preemptive and dialysed simultaneous pancreas and kidney transplant recipients. Does familiarity breed acceptance? The influence of policy on physicians’ attitudes toward newborn screening programs. Synthesis and biological evaluation of lisofylline (LSF) analogs as a potential treatment for Type 1 diabetes. Impact of Renin Angiotensin System Modulation on the Hyperfiltration State in Type 1 […]

Evidence for an Association Between Type 1 Diabetes and Premature Carotid Atherosclerosis in Childhood. Soluble vascular cell adhesion molecule-1 and soluble E-selectin are associated with micro- and macrovascular complications in Type 1 diabetic patients. Cholesterol oxides as biomarkers of oxidative stress in type 1 and type 2 diabetes mellitus. Early supernormal retinal oxygenation response in patients with diabetes. The 30-Year Natural History of Type 1 Diabetes Complications: The Pittsburgh Epidemiology of Diabetes Complications Study Experience. A Clinical Screening Tool Identifies Autoimmune Diabetes in Adults. The Belgrade childhood diabetes study – comparison of children with Type 1 diabetes with their siblings. […]

Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs. Free full text available in PDF format. Cure of chronic viral infection and virus-induced type 1 diabetes by neutralizing antibodies. Air pollution and type 1 diabetes in children. Independent effects of socioeconomic status and place of residence on the incidence of childhood type 1 diabetes in Western Australia. Childhood type 1 diabetes mellitus in Newfoundland and Labrador, Canada. Free radicals related effects and antioxidants in saliva and serum of adolescents with Type 1 diabetes mellitus. Arterial wall thickening and stiffening in children and adolescents with […]

A single transplantation of the islets can produce glycemic stability and reduction of basal insulin requirement. Preventive and Therapeutic Potential of p38{alpha} Selective MAPK Inhibitor in NOD Mice with Type 1 Diabetes. Free full text available in PDF format. Islet neogenesis: a potential therapeutic tool in type 1 diabetes. Dietary Proteins as Environmental Modifiers of Type 1 Diabetes Mellitus. Sequential kidney/islet transplantation: efficacy and safety assessment of a steroid-free immunosuppression protocol. Targeting type 1 diabetes before and at the clinical onset of disease. Prevalence and clinical characteristics of insulin-treated, anti-GAD-positive, type 2 diabetic subjects in an outpatient clinical department of […]

Information About the Latest Research Findings on Type 1 Diabetes Published in the Journal Science. See also Infused Spleen Cells Found Not to Impact Islet Recovery and Reversal of Type 1 Diabetes in Mice and Diabetes Studies Conflict on Power of Spleen Cells. Age at introduction of new foods and advanced beta cell autoimmunity in young children with HLA-conferred susceptibility to type 1 diabetes. Dietary risk factors for the emergence of type 1 diabetes-related autoantibodies in 21/2 year-old Swedish children. Aminoguanidine prevented impairment of blood antioxidant system in insulin-dependent diabetic rats. Production of islet-like structures from neonatal porcine pancreatic tissue […]

Cognitive and Neural Hippocampal Effects of Long-Term Moderate Recurrent Hypoglycemia. Therapy of diabetes mellitus : Pancreas transplantation, islet transplantation, stem cell and gene therapy. Failure of Transplanted Bone Marrow Cells to Adopt a Pancreatic �-Cell Fate. Decreased In Vitro Type 1 Immune Response Against Coxsackie Virus B4 in Children With Type 1 Diabetes. Increased Brain Monocarboxylic Acid Transport and Utilization in Type 1 Diabetes. Identical twins discordant for type 1 diabetes show a different pattern of in vitro CD56(+) cell activation. Insulin Sensitivity, Glucose Effectiveness, and Free Fatty Acid Dynamics Following Human Islet Transplantation for Type 1 Diabetes. Free full […]

The 24 March 2006 issue of Science contained three reports on studies that sought to replicate the work of Denise Faustman: Immunological Reversal of Autoimmune Diabetes Without Hematopoietic Replacement of � Cells. Reversal of Diabetes in Non-Obese Diabetic Mice Without Spleen Cell-Derived � Cell Regeneration. Islet Recovery and Reversal of Murine Type 1 Diabetes in the Absence of Any Infused Spleen Cell Contribution. Immunological Reversal of Autoimmune Diabetes Without Hematopoietic Replacement of � Cells. Reversal of Diabetes in Non-Obese Diabetic Mice Without Spleen Cell-Derived � Cell Regeneration. Islet Recovery and Reversal of Murine Type 1 Diabetes in the Absence of […]

Kidney disease rare with early type 1 diabetes onset summarizes Age at Onset of Childhood-Onset Type 1 Diabetes and the Development of End-Stage Renal Disease. Immune complexes containing modified lipoproteins are related to the progression of internal carotid intima-media thickness in patients with type 1 diabetes. Growing new endocrine pancreas in situ. Anti-CD38 autoantibodies in type? diabetes. Gene therapy for diabetes: reinventing the islet. Diabetic control after total pancreatectomy.