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Research News From May 29, 2005

Continuous Glucose Monitoring in Interstitial Subcutaneous Adipose Tissue and Skeletal Muscle Reflects Excursions in Cerebral Cortex. Environmental Triggers for Type 1 Diabetes. Therapeutic Neovascularization Using Cord Blood�Derived Endothelial Progenitor Cells for Diabetic Neuropathy. Association between a protein polymorphism in the start codon of the vitamin D receptor gene and severe diabetic retinopathy in C-peptide-negative type 1 diabetes. Frequency, Severity, and Morbidity of Hypoglycemia Occurring in the Workplace in People With Insulin-Treated Diabetes. Dose-Response Relationship of Oral Insulin Spray in Healthy Subjects. Long-Term Impact of Breast-Feeding on Body Weight and Glucose Tolerance in Children of Diabetic Mothers. Nephropathy, but not retinopathy, […]

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Research News From May 22, 2005

Scientists clone cells from human patients. See also Stem cell breakthrough and Stem cell breakthrough in UK and South Korea. Minocycline reduces proinflammatory cytokine expression, microglial activation, and caspase-3 activation in a rodent model of diabetic retinopathy. See also A Penn State College of Medicine study suggests that a common antibiotic called minocycline may slow or prevent diabetic retinopathy, a complication of diabetes that is the leading cause of blindness in people ages 20 to 74. Normalization of glucose post-transplantation of pig pancreatic anlagen into non-immunosuppressed diabetic rats depends on obtaining anlagen prior to embryonic day 35. See also Precise […]

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Research News From May 15, 2005

Insulin sparks autoimmunity. See summary at Study at UCDHSC Identifies Crucial Islet Target in Type 1 Diabetes; Finding Is Likely to Transform the Study of Diabetes Autoimmunity. See also CU team discovers crucial clue to diabetes; Health Sciences scientists find proof of trigger in Type 1. C-reactive protein concentration is not related to islet autoimmunity status in offspring of parents with type 1 diabetes. Can Continuous Glucose Monitoring Provide Objective Documentation Of Hypoglycemia Unawareness? Evaluation of metabolic control using a continuous subcutaneous glucose monitoring system in patients with type 1 diabetes mellitus who achieved insulin independence after islet cell transplantation. […]

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Research News From May 8, 2005

Pancreas donation for islet transplantation. Pancreas islet transplantation in patients with type 1 diabetes mellitus after kidney transplantation. Kidney-Pancreas Transplants: Is It So Difficult to Start a Program? Dynamics of diabetes-associated autoantibodies in young children with human leukocyte antigen-conferred risk of type 1 diabetes recruited from the general population. Bone calcium changes during diabetic ketoacidosis: A comparison with lactic acidosis due to volume depletion. Impact of insulin on microvascular blood flow and endothelial cell function in the postprandial state in patients with Type 1 diabetes. Increased plasma adiponectin concentrations are associated with microangiopathy in type 1 diabetic subjects. Beneficial autoimmunity […]

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Research News From May 1, 2005

Effects of Oral Insulin in Relatives of Patients With Type 1 Diabetes: The Diabetes Prevention Trial�Type 1 concluded that “…oral insulin did not delay or prevent type 1 diabetes.” Study shows natural glucose byproduct may prevent brain damage and cognitive impairment after diabetic coma. See also Pyruvate Administered After Severe Hypoglycemia Reduces Neuronal Death and Cognitive Impairment. Time-Action Profile of Inhaled Insulin in Comparison With Subcutaneously Injected Insulin Lispro and Regular Human Insulin. Living-Donor Islet Transplantation: A Newsmaker Interview With Shinichi Matsumoto, MD, PhD. Incretin hormones and insulin sensitivity. Producing Insulin from Neural Cells. Also available in PDF format. Differentiation […]

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Research News From April 24, 2005

Dietary manipulation of beta cell autoimmunity in infants at increased risk of type 1 diabetes: a pilot study. Insights into the acute cerebral metabolic changes associated with childhood diabetes. Differentiation of Insulin-Producing Cells from Human Neural Progenitor Cells. Association of childhood type 1 diabetes mellitus with a variant of PAX4: possible link to beta cell regenerative capacity. Psychosocial aspects of xenotransplantation: survey in adolescent recipients of porcine islet cells. Type 1 Diabetes in the Spanish Population: additional factors to Class II HLA-DR3 and -DR4. Free full text available in HTML and PDF formats. Structural-tridimensional study of yolk sac in pregnancies […]

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Research News From April 17, 2005

Vitamin D-binding protein gene polymorphism association with IA-2 autoantibodies in type 1 diabetes. The Spring 2005 issue of Diabetes Update from Diabetes UK explores work being done to find a vaccine to prevent type 1 diabetes. See also Vaccine gives hope to Type 1 diabetics. Diabetes-related antibodies in euglycemic subjects. Should We Be Performing Pancreas Transplants? Widening of foot processes in normoalbuminuric adolescents with type 1 diabetes. Researcher grows new insulin-secreting beta cells from pancreatic tissue. Scientists use transcription factors to increase insulin production in diabetic mice. Scientists at diabetes center find genetic defects in immunological tolerance. The Boston Globe […]

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Research News From April 10, 2005

Early infant diet and risk of type 1 diabetes mellitus in Belgrade children. Do microbes have a causal role in type 1 diabetes? is the free, full text article to a paper previously cited here. Clinical characteristics at onset of Type 1 diabetes in children diagnosed between 1977 and 2001 in the south-east region of Sweden. Clinical implications of N-(carboxymethyl)lysine, advanced glycation end product, in children and adolescents with type 1 diabetes. Human blood cells coaxed to produce insulin. Reluctance of French patients with type 1 diabetes to undergo pig pancreatic islet xenotransplantation. Transplantation of neonatal porcine islets and sertoli […]

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Research News From April 3, 2005

The role of the innate immunity in islet transplantation. Inflammatory gene expression in Coxsackievirus B-4-infected human islets of Langerhans. Regulatory T cells and type 1 diabetes. Predicting type 1 diabetes. Glycaemic effects of incretins in Type 1 diabetes mellitus A concise review, with emphasis on studies in humans. Human blood cells coaxed to produce insulin. Xenogenous transplantation of insular cells without immunosuppressive therapy in the treatment of insulin-dependent diabetes. TRIGR – Trial to Reduce the Incidence of type 1 diabetes in the Genetically at Risk. Clinical outcomes of phacoemulsification cataract surgery in diabetes patients: visual function (VF-14), visual acuity and […]

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Research News From March 27, 2005

Change in perceived health and functioning over time in patients with type I diabetes mellitus. The stages of type 1A diabetes: 2005. Maternal Efforts to Prevent Type 1 Diabetes in At-Risk Children. Autoantibody “Subspecificity” in Type 1 Diabetes: Risk for organ-specific autoimmunity clusters in distinct groups. Residual insulin secretion at diagnosis of type 1 diabetes is independently associated with both, age of onset and HLA genotype. Human leukocyte antigen class I B and C loci contribute to Type 1 Diabetes (T1D) susceptibility and age at T1D onset. Critical Role Macrophage Migration Inhibitory Factor (MIF) Activity in Experimental Autoimmune Diabetes. Free […]

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