Research News From December 7, 2016
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- Assessing the population impact of low rates of vitamin D supplementation on type 1 diabetes using a new statistical method. Free full text available in HTML and PDF formats.
- Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity. Free full text available in PDF format. See also Breakthrough in diabetes research: Pancreatic cells produce insulin instead of glucagon upon artemisinin treatment and Anti-malaria drugs could be linked to type 1 diabetes treatment.
- Glucose-stimulated expression of Txnip is mediated by carbohydrate response element-binding protein, p300, and histone H4 acetylation in pancreatic beta cells. Free full text available in HTML and PDF formats. See also CRISPR editing in pancreatic cells reduced cell death, increased insulin secretion.
- Increased DNA methylation variability in type 1 diabetes across three immune effector cell types. Free full text available in HTML and PDF formats.
- Targeted next-generation sequencing reveals MODY in up to 6.5% of antibody-negative diabetes cases listed in the Norwegian Childhood Diabetes Registry.
