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DIDMOAD

My 11 year old black lab has been living with diabetes for three and a half years and was under control until four months ago when her blood sugars crept up into the 500 mg/dl [mmol/L] range. Her doctor changed her to Ultralente twice a day, and she seems to do fine for three or four days with blood sugars around 200 mg/dl [11.1 mmol/L], but then she gets hypoglycemic, usually shortly before her next meal. Is this because we are using Ultralente?

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Is diabetes insipidus in combination with smaller than normal optic nerves enough to point to DIDMOAD?

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We would like to know answers to some questions about DIDMOAD.

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A friend was recently diagnosed with type 1. His mother and aunt both died of Wolfram’s syndrome. Even though his father is not a carrier, could he have further complications?

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My son, 11 years of age, was diagnosed with diabetes a year ago. He also has Optic Atrophy. The doctors here think he may have Wolfram’s. Is there any doctors or medical center in the South or in the USA that would see our son and help us determine if he truly has Wolfram’s?

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Is there a genetic screen available to a member of the public who is married to someone with high risk of being a carrier for Wolfram Syndrome? If not, how long might the couple need to wait for such a test to become available?

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I have been diagnosed with gastroparesis and have been unable to tolerate the medication (Reglan), but I have been told there is no other medication presently available. I have been unable to find much information about the condition and would appreciate any information that could be forwarded to me.

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I realize that there are other circumstances that affect blood sugar levels, but just as a guideline, the answer to three questions will be of great benefit to me.

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My 30 year old daughter, who has diabetes insipidus, also has optic atrophy but not deafness, and a pituitary tumor which causes the insipidus. If she would decide to have children, would they inherit this condition? Would they be born with it?

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My 22 month old daughter has been diagnosed with diabetes mellitus and diabetes insipidus. Any information help and advice would be greatly received, and I would like anyone on the list who has a child with both these types of diabetes to contact me.

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