
May 11, 2008
Type 2
Question from India:
I read about insulin oscillation. Many type 2 diabetics can have an irregular, increased and somewhat continual exposure of insulin to target cells. It is indicated in Wikipedia’s page on Insulin oscillations that “”Insulin release from pancreas is pulsatile with a period of 3-6 minutes…Disturbances of the insulin oscillations occur early in diabetes and may contribute to insulin resistance.” It looks as if abnormality in the above along with increased insulin’s exposure may also be contributing to getting insulin resistance. Is it correct?
Answer:
Yes. The abnormalities of insulin oscillation also occur with loss of first-phase insulin secretion in type 2 diabetes.
JTL