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January 23, 2001

Blood Tests and Insulin Injections

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Question from Medford, Massachusetts, USA:

I’m trying to find out are specifics on the chemistry used in different blood glucose meters. As more companies shift to electrochemical technologies I’m wondering how the technologies differ and even if they differ. Are they all based on oxidised glucose or peroxide or do they use other methods? Which do what and which are better?

Answer:

From: DTeam Staff

Meters on the market to read blood glucose usually do so by using a chemical reaction. The amount of glucose in the blood sample is then “measured” through an enzyme reaction with glucose oxidase. This either becomes a color that is read by the meter system or, most recently, has the meter respond to how much of a minute electric current is produced — then the meter translates that current to an equivalent blood glucose reading. All of these systems are proprietary. You may want to visit each of these company websites and see if there is more detailed information available.

If you go to PubMed, you could also look at the published systems in the medical literature, or, if you have access, in more detailed electrochemical engineering and clinical chemistry journals.

SB