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November 2, 2006

Exercise and Sports, Insulin

Question from India:

Should a type 2 diabetic with insulin resistance and persistent hyperglycemia be secreting continual and more insulin secretion than a normal healthy person in similar food intake? His tissues may also be exposed to continual insulin, when he is on medication program. In view of the indicated actions of insulin, being an anabolic hormone, more insulin may cause the increased uptake of glucose and aid in the increased store of energy as glycogen, fats and proteins. On the other side, more insulin may cause the decreased breakdown of these energy stores on need. How then can the body compensate for such a possible decreased breakdown of energy stores for some urgent need of more energy? Can the body's system maintain hyperglycemia to be used for some excessive need of energy in case of more insulin's action? Is it correct that exercising muscle needs no or lesser insulin for glucose uptake?

Answer:

It is correct that exercising muscle does not need insulin for glucose uptake. Insulin is helpful because it is the on demand hormone secreted in proximity to eating. Instant glucose utilization is provided by glycogen stores.

JTL